Integrated strontium-rubidium radioisotope infusion systems
DC CAFCFirst Claim
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1. A method of building an infusion system to deliver a rubidium radioactive eluate comprising:
- installing a first shielding compartment, a second shielding compartment, and a shielded well on a platform of a cart, wherein;
the first shielding compartment has a first opening facing vertically upwardly,the first opening is configured for a strontium-rubidium radioisotope generator to be inserted into and removed from the first shielding compartment,the second shielding compartment has a second opening facing vertically upwardly,the second opening is configured for a waste bottle to be inserted into and removed from the second shielding compartment,the first opening is located at a lower elevation than the second opening, andthe shielded well is configured to receive an eluate reservoir that is configured to receive a sample of the rubidium radioactive eluate;
configuring a computer with a touch screen display for the infusion system to;
fill the eluate reservoir in the shielded well on-board the cart with the sample of the rubidium radioactive eluate by pumping saline from a saline reservoir into the strontium-rubidium radioisotope generator via a saline tubing line thereby generating the rubidium radioactive eluate that is discharged through an eluate tubing line,determine a strontium breakthrough test result on the sample of the rubidium radioactive eluate filled into the eluate reservoir in the shielded well on-board the cart while the eluate reservoir remains in the shielded well on-board the cart, andnot allow a patient infusion if the strontium breakthrough test result is greater than or equal to an allowed limit.
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Abstract
Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.
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30 Claims
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1. A method of building an infusion system to deliver a rubidium radioactive eluate comprising:
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installing a first shielding compartment, a second shielding compartment, and a shielded well on a platform of a cart, wherein; the first shielding compartment has a first opening facing vertically upwardly, the first opening is configured for a strontium-rubidium radioisotope generator to be inserted into and removed from the first shielding compartment, the second shielding compartment has a second opening facing vertically upwardly, the second opening is configured for a waste bottle to be inserted into and removed from the second shielding compartment, the first opening is located at a lower elevation than the second opening, and the shielded well is configured to receive an eluate reservoir that is configured to receive a sample of the rubidium radioactive eluate; configuring a computer with a touch screen display for the infusion system to; fill the eluate reservoir in the shielded well on-board the cart with the sample of the rubidium radioactive eluate by pumping saline from a saline reservoir into the strontium-rubidium radioisotope generator via a saline tubing line thereby generating the rubidium radioactive eluate that is discharged through an eluate tubing line, determine a strontium breakthrough test result on the sample of the rubidium radioactive eluate filled into the eluate reservoir in the shielded well on-board the cart while the eluate reservoir remains in the shielded well on-board the cart, and not allow a patient infusion if the strontium breakthrough test result is greater than or equal to an allowed limit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification