Device having titania nanotube membrane for drug delivery
First Claim
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1. A method of preparing a titania nanotube membrane, the method comprising:
- growing a plurality of titania nanotubes on a first side of a titanium substrate under anodization conditions, such that a first end of each nanotube is closed and directly attached to the titanium substrate, and a second end of each nanotube is open; and
etching the titanium substrate on the side opposite the first side, under conditions sufficient to open the first end of a first group of the titania nanotubes, thereby preparing the titania nanotube membrane, wherein the nanotubes opened on the first end and the nanotubes opened on the second end is the only pathway for diffusion from one side of the titania nanotube membrane to the other, and wherein the first end of each nanotube is directly attached to the titanium substrate.
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Abstract
The present invention provides a device including a titania nanotube membrane having a plurality of titania nanotubes on a titanium substrate where the titania nanotubes are open at both ends and capable of allowing diffusion of liquids or solids from one side of the membrane to the other through the titania nanotubes. Methods of making the titania nanotube membrane are also provided.
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25 Claims
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1. A method of preparing a titania nanotube membrane, the method comprising:
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growing a plurality of titania nanotubes on a first side of a titanium substrate under anodization conditions, such that a first end of each nanotube is closed and directly attached to the titanium substrate, and a second end of each nanotube is open; and etching the titanium substrate on the side opposite the first side, under conditions sufficient to open the first end of a first group of the titania nanotubes, thereby preparing the titania nanotube membrane, wherein the nanotubes opened on the first end and the nanotubes opened on the second end is the only pathway for diffusion from one side of the titania nanotube membrane to the other, and wherein the first end of each nanotube is directly attached to the titanium substrate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 25)
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- 23. A titania nanotube membrane comprising a plurality of titania nanotubes directly attached to a titanium substrate, wherein each nanotube has a first end and a second end such that both the first end and second end of a first group of the titania nanotubes are open, wherein the first group of nanotubes is the only pathway for diffusion from one side of the titania nanotube membrane to the other.
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