Multi-pole synchronous pulmonary artery radiofrequency ablation catheter

• US 9,820,800 B2
• Filed: 03/27/2015
• Issued: 11/21/2017
• Est. Priority Date: 11/13/2012
• Status: Active Grant

• Current Assignee: PULNOVO MEDICAL (WUXI) CO., LTD.
• Original Assignee: PULNOVO MEDICAL (WUXI) CO., LTD.
• Inventors: Chen, Shaoliang
• Primary Examiner(s): DELLA, JAYMI E
• Application Number:
  US14/672,010
• Publication Number:
  US 20150272656A1
• Time in Patent Office: 970 Days
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/320069 for ablating tissue
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00345 Vascular system
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00613 Irreversible electroporation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00916 with means for switching or controlling the main function of the instrument or device
• CPC Class Codes: A61B 2018/00988 Means for storing information, e.g. calibration constants, or for preventing excessive use, e.g. usage, service life counter
• CPC Class Codes: A61B 2018/124 switching the output to different electrodes, e.g. sequentially
• CPC Class Codes: A61B 2018/1407 Loop
• CPC Class Codes: A61B 2018/144 : Wire
• CPC Class Codes: A61B 2018/1467 : using more than two electrodes on a single probe
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61N 1/06 : for high-frequency therapy

Abstract

A multi-pole synchronous pulmonary artery radiofrequency ablation catheter may comprise a control handle, a catheter body and an annular ring. One end of the catheter body may be flexible, and the flexible end of the catheter body may be connected to the annular ring. The other end of the catheter body may be connected to the control handle. A shape memory wire may be arranged in the annular ring. One end of the shape memory wire may extend to an end of the annular ring and the other end of the shape memory wire may pass through a root of the annular ring and be fixed on the flexible end of the catheter body. The annular ring may be provided with an electrode group. The device possesses advantages of simple operation, short operation time and controllable precise ablation. The device can be used to treat pulmonary hypertension with pulmonary denervation.

Claims

1. A controller for controlling ablation of a target tissue of a patient with an ablation device comprising at least a first electrode and a second electrode, the controller comprising:

a display configured to present a user interface; and

one or more computing devices operably coupled with the display and with the ablation device, the one or more computing devices configured to at least execute instructions comprising;

receiving, through the user interface, a selection of a patient profile corresponding to the patient from a plurality of patient profiles stored on the one or more computing devices, wherein the plurality of patient profiles comprise predetermined operational parameters associated with the patient for operating the ablation device, the predetermined operational parameters including a first power level sufficient for ablating the target tissue of the patient at a first location using the first electrode, and a second power level different from the first power level sufficient for ablating the target tissue of the patient at a second location using the second electrode,

displaying, through the user interface, selectable operational parameters for operating the ablation device,

directing power to the first electrode in response to receiving a selection of the first electrode through the user interface, wherein the power is directed to the first electrode at the first power level sufficient for ablating the target tissue of the patient at the first location, wherein the first location is selected from a group comprising a left lateral apex of a distal end of a main pulmonary artery, an anterior side of the left lateral wall of the distal end of the main pulmonary artery, and a posterior side of the left lateral wall of the distal end of the main pulmonary artery,

directing the power to the second electrode in response to receiving a selection of the second electrode through the user interface, wherein the power is directed to the second electrode at the second power level different from the first power level and sufficient for ablating the target tissue of the patient at the second location, wherein the second location is different from the first location.

2. The controller of claim 1, further comprising a battery configured to store the power at the first power level sufficient for ablation using the first electrode, wherein

the one or more computing devices are in communication with the battery and configured to direct the power from the battery to the first electrode.

3. The controller of claim 2, further comprising a housing enveloping the one or more computing devices and the battery, wherein the housing comprises a power connection port configured to receive the power at a level sufficient to charge the battery.

4. The controller of claim 3, wherein the one or more computing devices are configured to direct the power from the battery to the first electrode after the battery has finished charging.

5. The controller of claim 3, wherein the one or more computing devices are configured to direct the power to the first electrode before the battery has finished charging.

6. The controller of claim 1, wherein the ablation device further comprises at least a first sensor, and wherein the one or more computing devices are further configured to display through the user interface first electrode ablation information captured by the first sensor while the power is directed to the first electrode.

7. The controller of claim 6, wherein the one or more computing devices are further configured to store the first electrode ablation information with the patient profile.

8. The controller of claim 7, wherein the first electrode ablation information comprises a temperature.

9. The controller of claim 1, wherein the second location is selected from the group comprising the left lateral apex of the distal end of the main pulmonary artery, the anterior side of the left lateral wall of the distal end of the main pulmonary artery, and the posterior side of the left lateral wall of the distal end of the main pulmonary artery.

10. The controller of claim 1, wherein the predetermined operational parameters further include a third power level sufficient for ablating the target tissue at a third location using a third electrode, and

wherein the instructions further comprise directing power to the third electrode in response to receiving a selection of the third electrode through the user interface, wherein power is directed to the third electrode at the third power level different from the first or second power level and sufficient for ablating the target tissue of the patient at the third location, wherein the third location is different from the first and second locations and is selected from the group comprising the left lateral apex of the distal end of the main pulmonary artery, the anterior side of the left lateral wall of the distal end of the main pulmonary artery, and the posterior side of the left lateral wall of the distal end of the main pulmonary artery.

11. A computer-implemented method for ablating a target tissue of a patient with an ablation device comprising at least a first electrode and a second electrode, the method comprising:

under control of one more computing devices executing specific computer-executable instructions,

receiving, through a user interface presented on a display, a selection of a patient profile corresponding to a patient from a plurality of patient profiles stored on the one or more computing devices, wherein the patient profile comprises predetermined operational parameters associated with the patient for operating the ablation device, the predetermined operational parameters including a first power level sufficient for ablating the target tissue of the patient at a first location using the first electrode, and a second power level sufficient for ablating the target tissue of the patient at a second location using the second electrode,

displaying, through the user interface, selectable operational parameters for operating the ablation device,

directing power to the first electrode in response to receiving a selection of the first electrode through the user interface, wherein the power is directed to the first electrode at the first power level sufficient for ablating the target tissue of the patient at the first location, wherein the first location is selected from a group comprising a left lateral apex of a distal end of a main pulmonary artery, an anterior side of the left lateral wall of the distal end of the main pulmonary artery, and a posterior side of the left lateral wall of the distal end of the main pulmonary artery, and

directing the power to the second electrode in response to receiving a selection of the second electrode through the user interface, wherein the power is directed to the second electrode at the second power level different from the first power level sufficient for ablating the target tissue of the patient at the second location, wherein the second location is different from the first location.

12. The method of claim 11, wherein the power directed to the first electrode applies radiofrequency (RF) energy for ablation of sympathetic nerve fibers.

13. The method of claim 11, wherein the power directed to the first electrode applies ultrasonic energy for ablation of sympathetic nerve fibers.

14. The method of claim 11, wherein the power directed to the first electrode applies electroporation energy for ablation of sympathetic nerve fibers.

15. The method of claim 11, wherein the power directed to the first electrode applies ionizing energy for ablation of sympathetic nerve fibers.

16. The method of claim 11, wherein the second location is selected from the group comprising the left lateral apex of the distal end of the main pulmonary artery, the anterior side of the left lateral wall of the distal end of the main pulmonary artery, and the posterior side of the left lateral wall of the distal end of the main pulmonary artery.

17. The method of claim 11, wherein the predetermined operational parameters further include a third power level sufficient for ablating the target tissue at third location using a third electrode, and wherein the method further comprises:

directing power to the third electrode in response to receiving a selection of the third electrode through the user interface, wherein power is directed to the third electrode at the third power level different from the first or second power level and sufficient for ablating the target tissue of the patient at the third location, wherein the third location is different from the first and second locations and is selected from the group comprising the left lateral apex of the distal end of the main pulmonary artery, the anterior side of the left lateral wall of the distal end of the main pulmonary artery, and the posterior side of the left lateral wall of the distal end of the main pulmonary artery.

18. A computer-readable, non-transitory storage medium storing computer executable instructions that, when executed by one or more computer systems, configure the one or more computer systems to perform operations comprising:

receiving, through a user interface, a selection of a patient profile corresponding to a patient from a plurality of patient profiles stored on the one or more computing devices, wherein the patient profile comprises predetermined operational parameters associated with the patient for operating an ablation device comprising at least a first electrode and a second electrode, the predetermined operational parameters including a first power level sufficient for ablating the target tissue of the patient at a first location using the first electrode, and a second power level sufficient for ablating the target tissue of the patient at a second location using the second electrode;

displaying, through the user interface, selectable operational parameters for operating the ablation device;

directing power to the first electrode in response to receiving a selection of the first electrode through the user interface, wherein the power is directed to the first electrode at the first power level sufficient for ablating the target tissue of the patient at the first location, wherein the first location is selected from a group comprising a left lateral apex of a distal end of a main pulmonary artery, an anterior side of the left lateral wall of the distal end of the main pulmonary artery, and a posterior side of the left lateral wall of the distal end of the main pulmonary artery; and

directing the power to the second electrode in response to receiving a selection of the second electrode through the user interface, wherein the power is directed to the second electrode at the second power level different from the first power level sufficient for ablating the target tissue of the patient at the second location, wherein the second location is different from the first location.

19. The computer-readable, non-transitory storage medium of claim 18, wherein directing the power to the second electrode directs an amount of the power greater than an amount of the power directed to the first electrode.

20. The computer-readable, non-transitory storage medium of claim 18, wherein the second location is selected from the group comprising the left lateral apex of the distal end of the main pulmonary artery, the anterior side of the left lateral wall of the distal end of the main pulmonary artery, and the posterior side of the left lateral wall of the distal end of the main pulmonary artery.

21. The computer-readable, non-transitory storage medium of claim 18, wherein the predetermined operational parameters further include a third power level sufficient for ablating the target tissue at third location using a third electrode, and

wherein the operations performed further comprise directing power to the third electrode in response to receiving a selection of the third electrode through the user interface, wherein power is directed to the third electrode at the third power level different from the first or second power level and sufficient for ablating the target tissue of the patient at the third location, wherein the third location is different from the first and second locations and is selected from the group consisting of the left lateral apex of the distal end of the main pulmonary artery, the anterior side of the left lateral wall of the distal end of the main pulmonary artery, and the posterior side of the left lateral wall of the distal end of the main pulmonary artery.