Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
First Claim
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1. A method for improving glycemic control in a patient with type 2 diabetes mellitus comprising administering to the patient in need thereof a therapeutically effective amount of a pharmaceutical combination comprising:
- (a) lixisenatide or a pharmaceutically acceptable salt thereof, and(b) insulin glargine or a pharmaceutically acceptable salt thereof,wherein the patient'"'"'s type 2 diabetes mellitus is inadequately controlled after treatment with basal insulin at a dose of about 15 units to about 80 units per day for at least about 3 months.
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Abstract
The present invention refers to a pharmaceutical combination for use in glycemic control in diabetes type 2 patients.
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Citations
14 Claims
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1. A method for improving glycemic control in a patient with type 2 diabetes mellitus comprising administering to the patient in need thereof a therapeutically effective amount of a pharmaceutical combination comprising:
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(a) lixisenatide or a pharmaceutically acceptable salt thereof, and (b) insulin glargine or a pharmaceutically acceptable salt thereof, wherein the patient'"'"'s type 2 diabetes mellitus is inadequately controlled after treatment with basal insulin at a dose of about 15 units to about 80 units per day for at least about 3 months. - View Dependent Claims (2, 3, 4, 5, 6, 14)
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7. A method for improving glycemic control in a patient with type 2 diabetes mellitus, the method comprising administering to the patient in need thereof a therapeutically effective amount of a pharmaceutical combination comprising:
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(a) lixisenatide or a pharmaceutically acceptable salt thereof, and (b) insulin glargine or a pharmaceutically acceptable salt thereof, wherein the patient'"'"'s type 2 diabetes mellitus is inadequately controlled after treatment with basal insulin at a dose of about 15 units to about 80 units per day and metformin at a dose of at least about 1.0 g per day for at least about 3 months. - View Dependent Claims (8, 9, 10, 11, 12, 13)
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Specification