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System and method for optogenetic therapy

  • US 9,821,170 B2
  • Filed: 07/28/2014
  • Issued: 11/21/2017
  • Est. Priority Date: 11/21/2012
  • Status: Active Grant
First Claim
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1. A system for preventing hypertension in a patient, comprising:

  • a. an implantable optical applicator configured to be permanently coupled to at least one tissue structure such that it can deliver photons to at least one branch of the renal nerve plexus that has been genetically modified to have light sensitive protein;

    b. an implantable light source and an implantable power supply, the implantable light source being operatively intercoupled between the implantable power supply and the implantable optical applicator such that photons generated when the implantable light source is drawing current from the implantable power supply may be delivered to the implantable optical applicator;

    c. an implantable sensor configured to be deployed within the body of the patient and to provide an output signal that is correlated with the blood pressure of the patient; and

    d. an implantable controller operatively coupled to the implantable sensor and implantable light source, the implantable controller configured to cause the implantable light source to illuminate the light sensitive protein through the implantable light source and implantable optical applicator to at least partially inhibit action potential transmission within the at least one branch of the renal nerve plexus based at least in part upon the output signal received from the implantable sensor.

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