Apparatus and method for generating chemical signatures using differential desorption
First Claim
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1. A device comprising:
- a desorption ionization source adapted to generate a first stream of energetic particles at a first temperature and a second stream of energetic particles at a second temperature, where the desorption ionization source is adapted to direct the first stream of energetic particles towards a target area on the sorbent coated fiber, where the sorbent coated fiber has a length and a diameter, where the sorbent coated fiber has been in contact with a sample, where the first stream of energetic particles forms a plurality of first sample ions, where the desorption ionization source is adapted to direct the second stream of energetic particles towards the target area on the sorbent coated fiber, where the second stream of energetic particles forms a plurality of second sample ions; and
an analyzer, adapted to analyze one or both one or more of the plurality of first sample ions and one or more of the plurality of second sample ions.
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Abstract
The present invention is directed to a method and device to generate a chemical signature for a mixture of analytes. The present invention involves using a SPME surface to one or both absorb and adsorb the mixture of analytes. In an embodiment of the invention, the surface is then exposed to different temperature ionizing species chosen with appropriate spatial resolution to desorb a chemical signature for the mixture of analytes.
218 Citations
20 Claims
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1. A device comprising:
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a desorption ionization source adapted to generate a first stream of energetic particles at a first temperature and a second stream of energetic particles at a second temperature, where the desorption ionization source is adapted to direct the first stream of energetic particles towards a target area on the sorbent coated fiber, where the sorbent coated fiber has a length and a diameter, where the sorbent coated fiber has been in contact with a sample, where the first stream of energetic particles forms a plurality of first sample ions, where the desorption ionization source is adapted to direct the second stream of energetic particles towards the target area on the sorbent coated fiber, where the second stream of energetic particles forms a plurality of second sample ions; and an analyzer, adapted to analyze one or both one or more of the plurality of first sample ions and one or more of the plurality of second sample ions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A device comprising:
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a desorption ionization source adapted to generate a plurality of first sample ions and a plurality of second sample ions, where the plurality of first sample ions are formed from a first stream of energetic particles with a first temperature impacted a sorbent coated fiber and the plurality of second sample ions are formed from a second stream of energetic particles with a second temperature impacted the sorbent coated fiber; and an analyzer, adapted to analyze one or more of the plurality of first sample ions and the plurality of second sample ions. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18)
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19. A device comprising:
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a first desorption ionization source adapted to generate a plurality of first sample ions formed from a first stream of energetic particles with a first temperature impacting a sorbent coated fiber; a second desorption ionization source adapted to generate a plurality of second sample ions formed from a second stream of energetic particles with a second temperature impacting the sorbent coated fiber; and an analyzer, adapted to analyze one or more of the plurality of first sample ions and the plurality of second sample ions. - View Dependent Claims (20)
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Specification