Body cavity physiological measurement device

• US 9,826,936 B2
• Filed: 04/03/2015
• Issued: 11/28/2017
• Est. Priority Date: 04/03/2014
• Status: Active Grant

• Current Assignee: Beth Rosenshein
• Original Assignee: Beth Rosenshein
• Inventors: Rosenshein, Beth
• Primary Examiner(s): D ABREU, MICHAEL JOSEPH
• Application Number:
  US14/678,220
• Publication Number:
  US 20150282763A1
• Time in Patent Office: 970 Days
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/015 By temperature mapping of body part
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/1121 Determining geometric values, e.g. centre of rotation or angular range of movement
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/4331 of the cervix A61B5/435 takes precedence
• CPC Class Codes: A61B 5/6867 specially adapted to be attached or implanted in a specific body part A61B5/6847 takes precedence

Abstract

Provided herein is a self-contained physiological measuring device adapted for disposition within a patient body cavity, primarily the vagina, for an extended period of time (e.g., 6-48 hours or more). While disposed within the body cavity, the device periodically measures one or more physiological parameters at known locations within the body cavity. In addition to measuring such physiological parameters, the device is operative to store such measurements to memory for subsequent download/processing upon removal of the device from the body cavity and/or upon wireless interrogation.

Claims

1. A self contained physiological monitoring device adapted for temporary disposition within a vaginal cavity free of connection outside of the vaginal cavity, comprising:

a toroidal body adapted for insertion into the vaginal cavity free of connection outside of the vaginal cavity;

a battery attached to said toroidal body;

a memory device attached to said toroidal body; and

a control circuit attached to said toroidal and operatively connected to said battery and said memory device, wherein said battery, said memory device, and said control circuit are disposed within the vaginal cavity when said toroidal body is inserted within the vaginal cavity;

at least three sensors mounted at different locations about a periphery of said toroidal body, each said sensor being operatively connected to said battery and said control circuit, wherein each said sensor is operative to generate at least one sensor output of at least one physiological parameter for adjacent tissue;

at least three accelerometers mounted at different locations about the periphery said toroidal body, said accelerometers being operative to generate vector outputs for receipt by said control circuit;

wherein said control circuit is operative to;

utilize said vector outputs from said at least three accelerometers to determine an angular orientation of said toroidal body relative to the vaginal cavity wherein a first portion of said toroidal body is identified as being proximate to the posterior fornix of the vaginal cavity and a second portion of said toroidal body is identified as being proximate to the anterior fornix of the vaginal cavity;

determine a location of each said sensor about said periphery of said toroidal body relative to different regions of the vaginal cavity based on the angular orientation of the toroidal body relative to the vaginal cavity, wherein said sensors outputs are mapped to the different regions of the vaginal cavity; and

store the at least one sensor output from said sensors to the memory device connected to the toroidal body.

2. The device of claim 1, further comprising:

at least one reservoir chamber mounted proximate to the body, wherein the reservoir chamber administers one or more therapeutic agents.

3. The device of claim 2, further comprising:

a plurality of reservoir chambers mounted at said different angular locations about said toroidal body.

4. The device of claim 3, wherein said control circuit is operative to administer an agent from at least one of said plurality of reservoir chambers based on said angular orientation.

5. The device of claim 1, wherein said sensors are equally angularly spaced about said toroidal body.

6. The device of claim 5, wherein said accelerometer and said sensors are co-located at said different locations.

7. The device of claim 1, wherein said accelerometers comprise three-axis accelerometers.

8. The device of claim 1, wherein said control circuit is operative to calculate said angular orientation based on an estimated plane of the vaginal cavity when a user is disposed in known orientation.

9. The device of claim 1, further comprising:

a wireless interface operatively connected to the control circuit, wherein the wireless interface is at least operative to transmit data from the memory device.

10. The device of claim 1, wherein each sensor set comprises at least two of:

a temperature sensor;

a pH sensor;

a strain gauge; and

a pulse oximetry sensor.

11. A method for monitoring physiological parameters within a vaginal cavity, comprising:

inserting a measurement device having a toroidal body within a vaginal cavity of a user, wherein said measurement device is inserted within the vaginal cavity free of external connection outside the vaginal cavity;

positioning the user having the vaginally inserted measurement device in a known position, wherein a vaginal cavity of said user is substantially disposed in a known plane;

using vector signals from accelerometers disposed at three or more different positions about a periphery of said toroidal body of the measurement device to identify an angular orientation of said toroidal body relative to the vaginal cavity, wherein a first portion of said toroidal body is identified as being proximate to the posterior fornix of the vaginal cavity and a second portion of said toroidal body is identified as being proximate to the anterior fornix of the vaginal cavity;

based on said angular orientation, determining positions of sensors, disposed at different positions about the periphery of said toroidal body, relative to said vaginal cavity;

measuring at least one physiological parameter of tissue adjacent to each sensor;

mapping said at least one physiological parameter measured by each of said sensors to different locations within the vaginal cavity; and

storing said at least one physiological parameter as mapped to said different locations within the vaginal cavity to a memory device attached to said toroidal body and disposed within the vaginal cavity.

12. The method of claim 11, further comprising:

utilizing said motion signals to classify contractions or spasms.

13. The method of claim 12, wherein classifying said contractions or spasms further comprises:

utilizing said motion signals to identify an origination location of said contractions or spasms.

14. The method of claim 12, further comprising:

administering a controlled dosage volume of a therapeutic agent to one of said different location within the vaginal cavity from a reservoir supported by said toroidal body and disposed proximate to said location.

15. The method of claim 11, further comprising:

processing the physiological parameter measurements for different locations in the vaginal cavity with predetermined parameter measurements for said different locations to identify differences at one or more of said different locations.