×

Dry powder fibrin sealant

  • US 9,827,205 B2
  • Filed: 12/12/2009
  • Issued: 11/28/2017
  • Est. Priority Date: 12/12/2008
  • Status: Expired due to Fees
First Claim
Patent Images

1. A dry powder fibrin sealant composition, comprising:

  • a mixture of first microparticles that comprise fibrinogen and trehalose, andsecond microparticles that comprise thrombin and trehalose,wherein trehalose is the only stabilizing sugar in the first microparticles and second microparticles, andwherein the concentration of trehalose in the first microparticles is sufficient to preserve at least 70% of fibrinogen activity after exposure of the first microparticles to a 25 kGy dose of gamma irradiation delivered at a rate of 8 kGy/hour.

View all claims
  • 7 Assignments
Timeline View
Assignment View
    ×
    ×