pH buffer measurement system for hemodialysis systems
First Claim
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1. A pH-buffer measurement system for a dialysis system, comprising:
- at least one source for modifying the pH of a fluid entering the pH-buffer measurement system, wherein at least one source for modifying the pH is selected from an acid source and a base source, and wherein the acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid, and wherein the at least one source is in fluid communication with a dialysate flow path; and
a component, positioned downstream of the at least one source for modifying the pH of the fluid entering the pH-buffer measurement system, for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid;
wherein the fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity,a sorbent system in the dialysate flow path;
wherein the acid reacted fluid comprises at least a portion of the acid equivalent reacted with buffer in the fluid entering the pH-buffer measurement system, and the base reacted fluid comprises at least a portion of the base equivalent reacted with buffer in the fluid entering the pH-buffer measurement system.
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Abstract
A pH-buffer measurement system that has at least one source for modifying the pH of a fluid entering the system, the source selected from an acid source and a base source. The acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid. The source is in fluid communication with a flow path and a component for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid. The fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity.
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Citations
46 Claims
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1. A pH-buffer measurement system for a dialysis system, comprising:
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at least one source for modifying the pH of a fluid entering the pH-buffer measurement system, wherein at least one source for modifying the pH is selected from an acid source and a base source, and wherein the acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid, and wherein the at least one source is in fluid communication with a dialysate flow path; and a component, positioned downstream of the at least one source for modifying the pH of the fluid entering the pH-buffer measurement system, for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid;
wherein the fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity,a sorbent system in the dialysate flow path; wherein the acid reacted fluid comprises at least a portion of the acid equivalent reacted with buffer in the fluid entering the pH-buffer measurement system, and the base reacted fluid comprises at least a portion of the base equivalent reacted with buffer in the fluid entering the pH-buffer measurement system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A fluid therapy system, comprising:
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a dialyzer and a sorbent system in fluid communication with a pH-buffer measurement system to form a dialysate flow path;
wherein the pH-buffer measurement system comprises;at least one source for modifying the pH of a fluid entering the pH-buffer measurement system, the at least one source selected from an acid source and a base source wherein the acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid wherein the at least one source is in fluid communication with the dialysate flow path; and a component positioned downstream of the source for modifying the pH of the fluid entering the pH-buffer measurement system, for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid;
wherein the fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity; anda reconstitution system positioned downstream of the pH-buffer measurement system for providing a controlled amount of a buffer to be added to a dialysate to form a second dialysate with a predetermined concentration of the buffer prior to use in the dialyzer, wherein the pH-buffer measurement system determines the pH, buffer concentration or both of any one of the acid reacted fluid, the base reacted fluid, or the fluid entering the pH-buffer measurement system. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31)
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32. A method for determining a pH or buffer content of a fluid in a dialysate flow path, comprising the step of:
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modifying the pH of the fluid by adding an acid equivalent from an acid source to provide an acid reacted fluid or adding a base equivalent from a base source to provide a base reacted fluid; and determining at least one fluid characteristic of the acid reacted fluid or the base reacted fluid by taking a difference between a first value of the fluid characteristic and a second value of the fluid characteristic of the acid reacted fluid or the base reacted fluid; wherein at least one of the first value of the fluid characteristic and second value of the fluid characteristic is measured downstream of the acid source or the base source in the dialysate flow path, and wherein the acid reacted fluid comprises at least a portion of the acid equivalent reacted with buffer in the fluid entering the pH-buffer measurement system, and the base reacted fluid comprises at least a portion of the base equivalent reacted with buffer in the fluid entering the pH-buffer measurement system. - View Dependent Claims (33, 34, 35, 36)
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37. A fluid therapy system comprising:
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a fluid flow path in fluid communication with a dialyzer, a sorbent regeneration unit, a fluid characteristic management unit, the fluid characteristic management unit being positioned between the sorbent regeneration unit and the dialyzer along a fluid flow, and a reconstitution system positioned downstream of the fluid characteristic management unit. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46)
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Specification