Percutaneous administration device and method for injecting medicinal substances

• US 9,827,369 B2
• Filed: 03/16/2016
• Issued: 11/28/2017
• Est. Priority Date: 03/16/2016
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Cawthon, Dustin Christopher, Ding, Yuanpang Samuel
• Primary Examiner(s): LANDRY II, GERALD ERNEST
• Application Number:
  US15/071,853
• Publication Number:
  US 20170266369A1
• Time in Patent Office: 622 Days
• Field of Search: 604 9301, 604131, 604136, 60416401, 604174, 604180, 604192, 604263, 604264, 604272, 604506
• CPC Class Codes: A61K 9/7038 Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 5/14248 of the skin patch type

Abstract

A medical delivery device is provided for delivering a medicinal substance into a user'"'"'s body. An upper assembly includes a housing having a cavity configured for accommodating a needle. A lower assembly includes a receptacle member having an opening configured for accommodating insertion of the upper assembly, and a base member having an upper body and a recess formed on a top surface of the upper body for receiving the receptacle member. A base pad has an adhesive layer disposed on a lower surface of the pad, and being at least partially attached to a bottom side of the base member. The lower assembly is attached to a skin of the user using the base pad. As the upper assembly transitions from an upper position to a lower position relative to the lower assembly, the needle travels downwardly to penetrate the skin for facilitating administration of the medicinal substance.

Claims

1. A medical delivery device for delivering a medicinal substance into a user'"'"'s body, comprising:

an upper assembly including a housing having a cavity, and a needle disposed in said upper assembly;

a lower assembly including

a receptacle member having an opening configured for accommodating insertion of the housing of the upper assembly, and

a base member having an upper body and a recess formed on a top surface of the upper body for receiving the receptacle member; and

a base pad having an adhesive layer disposed on a lower surface of the pad, and being at least partially attached to a bottom side of the base member;

a biasing member disposed in said receptacle member and engaging said housing for biasing said housing away from said base member; and

a locking mechanism configured for releasably securing said housing in said lower position, said locking mechanism including at least one lower locking tab disposed on the receptacle member, and at least one corresponding upper locking tab disposed on the housing, such that when the tabs are in engagement, the housing is held in said lower position;

wherein the lower assembly is attached to a skin of the user using the base pad, and as the upper assembly is urged by a pressing force by the user from an upper position to a lower position relative to the lower assembly and overcoming force exerted by the biasing member, in the lower position, the needle disposed in the upper assembly travels downwardly to penetrate the skin for facilitating administration of the medicinal substance.

2. The device of claim 1, wherein a first throughbore is disposed on a bottom side of said receptacle member, and a second throughbore is disposed on the bottom side of the base member, both the first and second throughbores being dimensioned for slidingly receiving the needle.

3. The device of claim 1, wherein the housing has a cylindrical column extending downwardly transverse to a top inner surface of the housing.

4. The device of claim 1, wherein the receptacle member has a tubular column extending upwardly transverse to a bottom side of the receptacle member.

5. The device of claim 1, wherein the housing has a first flange extending outwardly from an outer circumference of the housing, and a second flange extending inwardly from an outer circumference of the receptacle member.

6. The device of claim 1, wherein at least one wing region is disposed on the receptacle member and is connected to the at least one lower locking tab on the receptacle member such that actuation of the wing region releases the locking mechanism by moving said locking tabs out of engagement with each other, causing the biasing member to return the housing to the upper position.

7. The device of claim 1, wherein at least one of the receptacle member and the housing includes at least one guide rib extending in a direction of travel of said housing relative to said receptacle member for guiding the at least one of the receptacle member and the housing upon activation of the device.

8. The device of claim 1, wherein the adhesive layer includes and gradually releases at least one first active substance for preparing the skin for penetration prior to activation of the medical delivery device.

9. The device of claim 8, wherein the at least one first active substance includes an antiseptic agent.

10. The device of claim 1, wherein the adhesive layer includes and gradually releases at least one second active substance during the administration of the medical substance for enhancing general health of the skin at or near an infusion site.

11. The device of claim 10, wherein the at least one second active substance includes at least one of:

an analgesic, a skin permeation enhancer, and a skin conditioning agent.

12. A medical delivery device for delivering a medicinal substance into a user'"'"'s body, comprising:

an upper assembly including a housing having a cavity, and a needle disposed in said upper assembly;

a lower assembly including

a receptacle member having an opening configured for accommodating insertion of the housing of the upper assembly;

a base member having an upper body and a recess formed on a top surface of the upper body for receiving the receptacle member; and

a base pad having an adhesive layer disposed on a lower surface of the pad, and being at least partially attached to a bottom side of the base member;

a biasing member disposed in the receptacle member and engaging the housing for biasing the housing away from the base member;

at least one lower locking tab on the receptacle constructed and arranged for releasably engaging an upper locking tab on the housing for securing the upper assembly in the lower position;

wherein the lower assembly is attached to a skin of the user using the base pad, and as the upper assembly is urged by the user from an upper position to a lower position relative to the lower assembly against force generated by the biasing member, the needle disposed in the upper assembly travels downwardly to penetrate the skin for facilitating administration of the medicinal substance, and the housing is releasably locked in position against action of the biasing member by engagement of said upper and lower locking tabs.

13. A medical delivery device for delivering a medicinal substance into a user'"'"'s body, comprising:

an upper assembly including a housing having a cavity, and a needle disposed in said upper assembly;

a lower assembly including

a receptacle member having an opening configured for accommodating insertion of the housing of the upper assembly;

a base member having an upper body and a recess formed on a top surface of the upper body for receiving the receptacle member; and

a base pad having an adhesive layer disposed on a lower surface of the pad, and being at least partially attached to a bottom side of the base member;

a biasing member disposed in the receptacle member and engaging the housing for biasing the housing away from the base member;

the upper assembly is urged by a pressing force by the user from an upper position to a lower position relative to the lower assembly and overcoming force exerted by the biasing member, in the lower position, the needle disposed in the upper assembly travels downwardly to penetrate the skin for facilitating administration of the medicinal substance;

at least one lower locking tab on the receptacle constructed and arranged for releasably engaging an upper locking tab on the housing for releasably securing said housing in said lower position; and

at least one wing region is disposed on the receptacle member and is connected to the at least one lower locking tab on the receptacle member such that actuation of the wing region releases the locking mechanism by moving said locking tabs out of engagement with each other, causing the biasing member to return the housing to the upper position.

14. A medical delivery device for delivering a medicinal substance into a user'"'"'s body, comprising:

an upper assembly including a housing having a cavity, and a needle disposed in said upper assembly;

a lower assembly including

a receptacle member having an opening configured for accommodating insertion of the housing of the upper assembly, and

a base member having an upper body and a recess formed on a top surface of the upper body for receiving the receptacle member; and

a base pad having an adhesive layer disposed on a lower surface of the pad, and being at least partially attached to a bottom side of the base member;

a biasing member disposed in said receptacle member and engaging said housing for biasing said housing away from said base member; and

a locking mechanism including at least one lower locking tab on said receptacle member configured for releasably engaging and securing said housing in said lower position; and

at least one wing region is disposed on the receptacle member and is connected to said at least one lower locking tab on the receptacle member such that actuation of the wing region releases the locking mechanism by moving said at least one locking tab out of engagement with said housing, causing the biasing member to return the housing to the upper position;

wherein the lower assembly is attached to a skin of the user using the base pad, and as the upper assembly is urged by a pressing force by the user from an upper position to a lower position relative to the lower assembly and overcoming force exerted by the biasing member, in the lower position, the needle disposed in the upper assembly travels downwardly to penetrate the skin for facilitating administration of the medicinal substance.

15. The device of claim 14, wherein a first throughbore is disposed on a bottom side of said receptacle member, and a second throughbore is disposed on the bottom side of the base member, both the first and second throughbores being dimensioned for slidingly receiving the needle.

16. The device of claim 14, wherein the housing has a cylindrical column extending downwardly transverse to a top inner surface of the housing.

17. The device of claim 14, wherein the receptacle member has a tubular column extending upwardly transverse to a bottom side of the receptacle member.

18. The device of claim 14, wherein the housing has a first flange extending outwardly from an outer circumference of the housing, and a second flange extending inwardly from an outer circumference of the receptacle member.

19. The device of claim 14, wherein at least one of the receptacle member and the housing includes at least one guide rib extending in a direction of travel of said housing relative to said receptacle member for guiding the at least one of the receptacle member and the housing upon activation of the device.

20. The device of claim 14, wherein the adhesive layer includes and gradually releases at least one second active substance during the administration of the medical substance for enhancing general health of the skin at or near an infusion site, wherein the at least one second active substance includes at least one of:

an analgesic, a skin permeation enhancer, and a skin conditioning agent.