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Fluidic systems and methods for analyses

  • US 9,827,564 B2
  • Filed: 06/29/2016
  • Issued: 11/28/2017
  • Est. Priority Date: 02/02/2009
  • Status: Active Grant
First Claim
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1. A multiplex assay system comprising:

  • an article supporting solid-phase assays, said article comprising a rigid planar substrate and comprising two or more different liquid containment regions, each liquid containment region comprising at least one analysis region that can be interrogated optically, each analysis region having one or more binding partners associated with a surface of the substrate, wherein said binding partners hind one or more analytes present in a sample in the liquid containment region, and wherein, for at least one liquid containment region, the one or more analytes is selected from the group consisting of prostate specific antigen (PSA), free PSA, complexed-PSA, pro-PSA, and human kallikrein protein (hk2); and

    an optical device configured to supply collimated light to illuminate an analysis region of the two or more liquid containment regions and detect light from the illuminated analysis region.

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