Driving patient compliance with therapy
First Claim
1. A method for determining a patient'"'"'s compliance with a cholesterol lowering therapy and treating the patient, the method comprising:
- conducting a first assay to determine a level of a cholesterol absorption sterol and a level of a cholesterol production sterol in a first sample obtained from a patient prior to undergoing a cholesterol lowering therapy;
comparing the level of the cholesterol absorption sterol against the level of the cholesterol production sterol to classify the patient as a balanced producer, an over producer, or an over-absorber of cholesterol;
conducting a second assay to determine a cholesterol level in a second sample obtained from the patient after the patient has started undergoing the cholesterol lowering therapy;
identifying the patient as non-compliant with the cholesterol lowering therapy when the patient'"'"'s cholesterol level has not decreased as expected compared to a prior cholesterol level taken from the patent before undergoing the cholesterol lowering therapy and given the patient'"'"'s classification; and
administering an alternative therapy to the patient in response to identifying the patient as non-compliant with the cholesterol lowering therapy.
1 Assignment
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Accused Products
Abstract
Methods of the invention involve determining a patient'"'"'s compliance with a cholesterol lowering therapy. In certain aspects, the invention provides methods that involve conducting a first assay to determine a cholesterol biomarker level in a first sample from a patient prior to the patient undergoing a cholesterol lowering therapy. The methods may also involve conducting a second assay to determine a cholesterol level in a second sample obtained from the patient after the patient has started undergoing a cholesterol lowering therapy. Additionally, the methods involve associating the cholesterol level and the cholesterol biomarker level in which the association allows for the determination of the patient'"'"'s compliance with the cholesterol lowering therapy.
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Citations
9 Claims
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1. A method for determining a patient'"'"'s compliance with a cholesterol lowering therapy and treating the patient, the method comprising:
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conducting a first assay to determine a level of a cholesterol absorption sterol and a level of a cholesterol production sterol in a first sample obtained from a patient prior to undergoing a cholesterol lowering therapy; comparing the level of the cholesterol absorption sterol against the level of the cholesterol production sterol to classify the patient as a balanced producer, an over producer, or an over-absorber of cholesterol; conducting a second assay to determine a cholesterol level in a second sample obtained from the patient after the patient has started undergoing the cholesterol lowering therapy; identifying the patient as non-compliant with the cholesterol lowering therapy when the patient'"'"'s cholesterol level has not decreased as expected compared to a prior cholesterol level taken from the patent before undergoing the cholesterol lowering therapy and given the patient'"'"'s classification; and administering an alternative therapy to the patient in response to identifying the patient as non-compliant with the cholesterol lowering therapy. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification