Variably bulbous vascular treatment devices

• US 9,833,251 B2
• Filed: 10/29/2015
• Issued: 12/05/2017
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Insera Therapeutics, Inc.
• Original Assignee: Insera Therapeutics, Inc.
• Inventors: Janardhan, Vallabh, Janardhan, Vikram
• Primary Examiner(s): Miles, Jonathan
• Application Number:
  US14/926,980
• Publication Number:
  US 20160045212A1
• Time in Patent Office: 768 Days
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/22032 having inflatable gripping elements balloon catheters A61M25/10
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/32056 Surgical snare instruments for removing or smashing calculi A61B2017/2212; tonsillotomes A61B17/26
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00641 for closing fistulae, e.g. anorectal fistulae
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/22001 Angioplasty, e.g. PCTA
• CPC Class Codes: A61B 2017/22002 preventing restenosis
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22035 for retrieving or repositioning foreign objects
• CPC Class Codes: A61B 2017/22067 : Blocking; Occlusion A61B2017/22054 takes precedence
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 90/39 : Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/011 : Instruments for their placement or removal
• CPC Class Codes: A61F 2002/018 : made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61M 1/74 : Suction control underwater drainage A61M1/61
• CPC Class Codes: A61M 1/84 : Drainage tubes; Aspiration tips for negative pressure wound therapy A61M1/90; for surgical cutting instruments A61B17/32
• CPC Class Codes: A61M 2025/0042 : Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2202/06 : Solids
• CPC Class Codes: A61M 2207/10 : Device therefor
• CPC Class Codes: A61M 2210/12 : Blood circulatory system
• CPC Class Codes: A61M 25/0023 : by the form of the lumen, e.g. cross-section, variable diameter
• CPC Class Codes: A61M 25/10 : Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 29/00 : Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00
• CPC Class Codes: B23K 26/083 : Devices involving movement of the workpiece in at least one axial direction
• CPC Class Codes: B23K 26/14 : using a fluid stream, e.g. a jet of gas, in conjunction with the laser beam; Nozzles therefor B23K26/12 takes precedence
• CPC Class Codes: B23K 26/142 : for the removal of by-products
• CPC Class Codes: B23K 26/1435 : involving specially adapted flow control means
• CPC Class Codes: B23K 26/146 : the fluid stream containing a liquid
• CPC Class Codes: B23K 26/20 : Bonding soldering by means of radiant energy B23K1/005; joining of preformed plastics parts by heating using laser beam B29C65/16
• CPC Class Codes: B23K 26/38 : by boring or cutting
• CPC Class Codes: B26F 3/004 : by means of a fluid jet methods for use of abrasive blasting for cutting B24C1/045; guns for abrasive fluid jets B24C5/02; perforating by non-mechanical means, e.g. by fluid jet B26F1/26
• CPC Class Codes: D04C 1/06 : Braid or lace serving particular purposes
• CPC Class Codes: D04C 1/12 : Cords, lines, or tows
• CPC Class Codes: D04C 3/48 : Auxiliary devices
• CPC Class Codes: D10B 2403/0333 : with tubular portions of variable diameter or distinct axial orientation
• CPC Class Codes: D10B 2509/06 : Vascular grafts; stents
• CPC Class Codes: Y10T 137/8376 : Combined
• CPC Class Codes: Y10T 137/85954 : Closed circulating system
• CPC Class Codes: Y10T 156/10 : Methods of surface bonding and/or assembly therefor
• CPC Class Codes: Y10T 29/49913 : by constricting outer annulus
• CPC Class Codes: Y10T 29/49995 : Shaping one-piece blank by removing material
• CPC Class Codes: Y10T 82/2521 : Bar feeder

Abstract

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Claims

1. A device for treating a thrombus in a vessel, the device comprising:

a distal portion including a plurality of wires woven to form a textile structure having a collapsed state and an expanded state, the textile structure comprising six self-expanding bulbs having three or more sizes in the expanded state, at least some of the self-expanding bulbs having a spherical shape in the expanded state, and

a proximal portion coupled to the distal portion.

2. The device of claim 1, wherein the three or more sizes of said self-expanding bulbs are repeated two or more times.

3. The device of claim 1, wherein the proximal portion comprises a multi-filament hybrid.

4. The device of claim 1, wherein the plurality of wires include radiopaque wires and shape-memory wires.

5. The device of claim 4, wherein the radiopaque wires are clustered to enhance visibility under x-ray.

6. The device of claim 1, wherein the proximal portion comprises a multi-filament hybrid, and wherein the plurality of wires comprises shape memory wires and radiopaque wires.

7. A device for treating a thrombus in a vessel, the device comprising:

a distal portion including a plurality of wires woven to form a textile structure having a collapsed state and an expanded state, the textile structure comprising five to ten self-expanding bulbs each having a spherical shape or an oblong shape in the expanded state, the five to ten self-expanding bulbs having three or more sizes in the expanded state, and

a proximal portion coupled to the distal portion.

8. The device of claim 7, wherein the textile structure comprises six said self-expanding bulbs.

9. The device of claim 7, wherein the textile structure comprises ten said self-expanding bulbs.

10. The device of claim 7, wherein the proximal portion comprises a multi-filament hybrid, wherein the textile fabric comprises six said self-expanding bulbs, wherein the plurality of wires comprises shape memory wires and radiopaque wires, and wherein the radiopaque wires are clustered to enhance visibility under x-ray.

11. A device for treating a thrombus in a vessel, the device comprising:

a distal portion including a plurality of wires woven to form a textile structure having a collapsed state and an expanded state, the textile structure comprising five to ten self-expanding bulbs having three or more sizes in the expanded state, and

a proximal portion coupled to the distal portion.

12. The device of claim 11, wherein the three or more sizes of said self-expanding bulbs are repeated two or more times.

13. The device of claim 12, wherein at least some of the three or more sizes of said self-expanding bulbs are repeated three or more times.

14. The device of claim 11, wherein the textile structure comprises six said self-expanding bulbs.

15. The device of claim 11, wherein the textile structure comprises ten said self-expanding bulbs.

16. The device of claim 11, wherein the self-expanding bulbs have four sizes.

17. The device of claim 11, wherein at least some of the self-expanding bulbs have a spherical shape.

18. The device of claim 11, wherein the plurality of wires include radiopaque wires and shape-memory wires.

19. The device of claim 18, wherein the radiopaque wires are clustered to enhance visibility under x-ray.

20. The device of claim 11, wherein the proximal portion comprises a multi-filament hybrid, wherein the textile structure comprises six said self-expanding bulbs, wherein at least one of the self-expanding bulbs has a spherical shape in the expanded state, and wherein the plurality of wires comprises shape memory wires and radiopaque wires.