Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods
First Claim
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1. A method for treating a patient, comprising:
- reducing or modifying an organ dysfunction of an identified organ in the patient by applying or directing application of an electrical signal to a spinal cord of the patient via an implanted signal delivery device, at a vertebral level associated with the identified organ, the electrical signal having a frequency of from about 1.5 kHz to about 100 kHz, wherein reducing or modifying the organ dysfunction includes modifying an imbalance in the patient'"'"'s autonomic system by normalizing a combined effect of the patient'"'"'s sympathetic and parasympathetic systems.
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Abstract
Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods. A method for treating a patient in accordance with a particular embodiment includes selecting a neural modulation site to include a neural population of the patient'"'"'s spinal cord, and selecting parameters of a neural modulation signal to at least reduce an autonomic system deficit in the patient.
395 Citations
25 Claims
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1. A method for treating a patient, comprising:
reducing or modifying an organ dysfunction of an identified organ in the patient by applying or directing application of an electrical signal to a spinal cord of the patient via an implanted signal delivery device, at a vertebral level associated with the identified organ, the electrical signal having a frequency of from about 1.5 kHz to about 100 kHz, wherein reducing or modifying the organ dysfunction includes modifying an imbalance in the patient'"'"'s autonomic system by normalizing a combined effect of the patient'"'"'s sympathetic and parasympathetic systems. - View Dependent Claims (2, 3, 13, 16, 19, 22)
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4. A method for treating a patient, comprising:
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implanting a signal delivery device at a location proximate to a vertebral level of the patient'"'"'s spinal cord associated with an organ in the patient identified as having an organ dysfunction; and directing an electrical signal to the patient'"'"'s spinal cord at the vertebral level and at a frequency in a range of from about 1.5 kHz to about 100 kHz to reduce or modify the organ dysfunction by normalizing a combined effect of the patient'"'"'s sympathetic and parasympathetic systems. - View Dependent Claims (5, 6, 7, 8, 9, 10, 14, 17, 20, 23, 25)
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11. A method for evaluating a patient'"'"'s pain, comprising:
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directing an electrical therapy signal to the patient'"'"'s spinal cord via an implanted signal delivery device to reduce or inhibit pain in the patient, the electrical therapy signal having a frequency of from about 1.5 kHz to about 100 kHz; receiving feedback corresponding to an autonomic system response by the patient to the electrical therapy signal, wherein the autonomic system response is a reduction or modification of an autonomic system deficit achieved by normalizing a combined effect of the patient'"'"'s sympathetic and parasympathetic systems; and based at least in part on the feedback, identifying a characteristic of the patient'"'"'s pain response to the electrical therapy signal.
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12. A method for treating a patient having an organ identified as having an organ dysfunction by reducing or modifying the patient'"'"'s organ dysfunction, the method comprising:
applying or directing application of an electrical signal to a spinal cord region of the patient via an implanted signal delivery device, the electrical signal having a frequency of from about 1.5 kHz to about 100 kHz, wherein reducing or modifying the patient'"'"'s organ dysfunction includes normalizing a combined effect of the patient'"'"'s sympathetic and parasympathetic systems. - View Dependent Claims (15, 18, 21, 24)
Specification