Devices, systems and methods for locating and interacting with medicament delivery systems

• US 9,836,948 B2
• Filed: 12/14/2016
• Issued: 12/05/2017
• Est. Priority Date: 12/27/2012
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Kaleo, Inc.
• Inventors: Edwards, Eric S., Edwards, Evan T., Licata, Mark J., Meyers, Paul F.
• Primary Examiner(s): HUNNINGS, TRAVIS R
• Application Number:
  US15/379,282
• Publication Number:
  US 20170092101A1
• Time in Patent Office: 356 Days
• CPC Class Codes: A61M 11/007 Syringe-type or piston-type sprayers or atomisers
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0001 Details of inhalators; Constructional features thereof
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/43 making noise when used correctly
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 : by visual feedback
• CPC Class Codes: A61M 2205/587 : Lighting arrangements
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2205/8212 : with means or measures taken for minimising energy consumption
• CPC Class Codes: A61M 2230/04 : Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/20 : Blood composition characteristics
• CPC Class Codes: A61M 2230/201 : Glucose concentration
• CPC Class Codes: A61M 2230/42 : Rate
• CPC Class Codes: A61M 5/20 : Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2053 : Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/31 : Details
• CPC Class Codes: A61M 5/3157 : Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/3202 : Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/5086 : for indicating if defective, used, tampered with or unsterile
• CPC Class Codes: G08B 21/185 : Electrical failure alarms
• CPC Class Codes: G09B 9/00 : Simulators for teaching or training purposes for the use of weapons F41; computing aspects G06; protocols for games, networked simulations or virtual reality H04L67/131
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: H04B 1/3827 : Portable transceivers
• CPC Class Codes: H04W 4/80 : Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

In some embodiments, a method includes establishing a communications link between a computing device and an adapter. The adapter is configured to receive at least a portion of a medicament delivery device. A wireless signal is received to maintain the communications link. A relative position between the computing device and the adapter is determined. An alarm is produced when the wireless signal is not received within a time period. The alarm is based on the relative position between the computing device and the adapter.

Claims

1. A method, comprising:

establishing a communications link, via a short-range wireless protocol, between a mobile computing device and a medicament delivery device, the mobile computing device including a touchscreen, the medicament delivery device including a case and an electronic circuit system, the case configured to receive at least a portion of the medicament delivery device, the electronic circuit system including a radio;

receiving a wireless signal from the radio, the wireless signal associated with removal of the medicament delivery device from the case;

producing, via at least one of the mobile computing device or the electronic circuit system, an alarm indicating that the medicament delivery device is in use;

producing, via the touchscreen and after the receiving the wireless signal, a prompt associated with a use instruction of the medicament delivery device;

receiving, in response to the prompt, a user input; and

transmitting, in response to the user input and via the touchscreen, the use instruction.

2. The method of claim 1, wherein the medicament delivery device is any one of an auto-injector, a nasal delivery device or an inhaler.

3. The method of claim 1, wherein the medicament delivery device is an auto-injector configured to deliver at least one of a dose of epinephrine, a dose of naloxone, or a dose of glucagon.

4. The method of claim 1, wherein the prompt is a first prompt, the method further comprising:

producing, via the touchscreen, a second prompt associated with any one of an emergency phone number or an emergency contact.

5. The method of claim 1, further comprising:

determining, based at least in part on the wireless signal, a location of the case; and

producing, via the mobile computing device, a location alert indicating the location.

6. The method of claim 5, wherein the determining is based on any one of a strength of the wireless signal, a direction of the wireless signal, or a global positioning sensor (GPS) signal associated with the receiving the wireless signal.

7. The method of claim 1, wherein:

the touchscreen is configured to display a lock screen having a password prompt, access to the mobile computing device being limited until a password is entered in response to the password prompt; and

the prompt is an emergency prompt providing access to the mobile computing device without entry of the password.

8. A method, comprising:

establishing a communications link, via a short-range wireless protocol, between a mobile computing device and a medicament delivery device, the mobile computing device including a touchscreen, the medicament delivery device including an actuator and an electronic circuit system, the actuator configured to initiate delivery of a medicament, the electronic circuit system including a radio and a sensor, the sensor configured to produce an actuation signal in response to movement of the actuator;

receiving a wireless signal from the radio, the wireless signal in response to the actuation signal;

producing, via the touchscreen and in response to the wireless signal, an emergency prompt associated with a use of the medicament delivery device;

receiving, in response to the emergency prompt, a user input; and

transmitting, in response to the user input and via the touchscreen, an instruction.

9. The method of claim 8, further comprising:

producing, via at least one of the mobile computing device or the electronic circuit system, an alarm in response to the actuation signal indicating the use of the medicament delivery device.

10. The method of claim 8, wherein the medicament delivery device is any one of an auto-injector, a nasal delivery device or an inhaler.

11. The method of claim 8, wherein the medicament delivery device is an auto-injector configured to deliver at least one of a dose of epinephrine, a dose of naloxone, or a dose of glucagon.

12. The method of claim 8, wherein the emergency prompt is a first emergency prompt, the method further comprising:

producing, via the touchscreen, a second emergency prompt associated with any one of an emergency phone number or an emergency contact.

13. The method of claim 8, wherein:

the touchscreen is configured to display a lock screen having a password prompt, access to the mobile computing device being limited until a password is entered in response to the password prompt; and

the emergency prompt provides access to the mobile computing device without entry of the password.

14. The method of claim 8, wherein:

the sensor is a switch; and

the actuator includes a first portion configured to initiate delivery of the medicament and a second portion configured to contact the switch.

15. A method, comprising:

establishing a communications link, via a short-range wireless protocol, between a mobile computing device and a medicament delivery device, the mobile computing device including a touchscreen configured to display a lock screen having a password prompt, access to the mobile computing device being limited until a password is entered in response to the password prompt, the medicament delivery device including an actuator and an electronic circuit system, the actuator configured to initiate delivery of a medicament, the electronic circuit system including a radio and a sensor, the sensor configured to produce an actuation signal in response to movement of the actuator;

receiving a wireless signal from the radio, the wireless signal in response to the actuation signal; and

producing, via the touchscreen and in response to the wireless signal, an emergency prompt providing access to the mobile computing device without entry of the password, the emergency prompt associated with a use of the medicament delivery device.

16. The method of claim 15, further comprising:

receiving, in response to the emergency prompt, a user input; and

transmitting, in response to the user input and via the touchscreen, an instruction.

17. The method of claim 16, further comprising:

producing, via at least one of the mobile computing device or the electronic circuit system, an alarm in response to the actuation signal indicating the use of the medicament delivery device.

18. The method of claim 15, wherein the medicament delivery device is any one of an auto-injector, a nasal delivery device or an inhaler.

19. The method of claim 15, wherein the medicament delivery device is an auto-injector configured to deliver at least one of a dose of epinephrine, a dose of naloxone, or a dose of glucagon.

20. The method of claim 15, further comprising:

receiving, in response to the emergency prompt, a user input; and

transmitting from the mobile computing device a notification to be received by an emergency personnel.

21. The method of claim 20, wherein:

the sensor is a switch; and

the actuator includes a first portion configured to initiate delivery of the medicament and a second portion configured to contact the switch.