Methods, devices and systems for pulmonary delivery of active agents
First Claim
1. An inhaler for use in delivering a series of at least two active agents released from at least first and second substances, said first substance contained in a first cartridge and said second substance contained in a second cartridge, the inhaler comprising:
- a vapor chamber configured for being in fluid communication with at least one of said first and second cartridges and in fluid communication with an output of said inhaler for delivery of at least one of said first and second active agents therethrough;
a memory in which dosing data for administering said first and second active agents is stored, said dosing data including defined vaporized amounts of said first and second active agents selected for inducing a predetermined therapeutic effect in said user, said dosing data including provision of said second active agent subsequently to provision of said first active agent, said first and second active agents to be provided at different inhalation events;
a controller in communication with said memory, said controller configured to effect delivery of said first active agent to the user and to sequentially effect delivery of said second active agent to the user according to said dosing data;
said controller configured to automatically adjust at least one of said vaporized amounts from said defined vaporized amount and/or adjust a timing for said delivery of said first and second active agents to provide a combination suitable for inducing said predetermined therapeutic effect in said user.
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Accused Products
Abstract
Provided herein is a system that includes a metered dose inhaler device for pulmonary delivering to a subject at least one pre-determined vaporized amount of at least one pharmacologically active agent being in a plant material, wherein vaporization is effected by controllably heating the plant material so as to vaporize a pre-determined vaporized amount of the agent; the system further includes a controller in communication with the inhaler device, configured to control the pre-determined vaporized amount based on data indicative of at least one pharmacodynamic effect induced by the agent in the subject.
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Citations
30 Claims
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1. An inhaler for use in delivering a series of at least two active agents released from at least first and second substances, said first substance contained in a first cartridge and said second substance contained in a second cartridge, the inhaler comprising:
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a vapor chamber configured for being in fluid communication with at least one of said first and second cartridges and in fluid communication with an output of said inhaler for delivery of at least one of said first and second active agents therethrough; a memory in which dosing data for administering said first and second active agents is stored, said dosing data including defined vaporized amounts of said first and second active agents selected for inducing a predetermined therapeutic effect in said user, said dosing data including provision of said second active agent subsequently to provision of said first active agent, said first and second active agents to be provided at different inhalation events; a controller in communication with said memory, said controller configured to effect delivery of said first active agent to the user and to sequentially effect delivery of said second active agent to the user according to said dosing data; said controller configured to automatically adjust at least one of said vaporized amounts from said defined vaporized amount and/or adjust a timing for said delivery of said first and second active agents to provide a combination suitable for inducing said predetermined therapeutic effect in said user. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification