Method and system for image processing and patient-specific modeling of blood flow
First Claim
1. A computer-implemented method for determining a hemodynamic pressure quantity, the method comprising:
- acquiring angiography data from a patient at a first physiological state of the patient, the first physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, the angiography data comprising x-ray angiography data, magnetic resonance angiography data, and/or computed tomographic angiography data;
determining, by a processor, a first flow in a blood vessel of the patient based on the angiography data, wherein the first flow corresponds to the first physiological state of the patient;
determining, by the processor, a second flow in a blood vessel based on scaling the first flow by a numerical factor from the first physiological state to a second physiological state, the second physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, wherein the second flow corresponds to the second physiological state of the patient that is different from the first physiological state of the patient;
determining, by the processor, the hemodynamic pressure quantity based on the second flow; and
reporting the hemodynamic pressure quantity.
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Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient'"'"'s heart, and create a three-dimensional model representing at least a portion of the patient'"'"'s heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient'"'"'s heart and determine a fractional flow reserve within the patient'"'"'s heart based on the three-dimensional model and the physics-based model.
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Citations
18 Claims
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1. A computer-implemented method for determining a hemodynamic pressure quantity, the method comprising:
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acquiring angiography data from a patient at a first physiological state of the patient, the first physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, the angiography data comprising x-ray angiography data, magnetic resonance angiography data, and/or computed tomographic angiography data; determining, by a processor, a first flow in a blood vessel of the patient based on the angiography data, wherein the first flow corresponds to the first physiological state of the patient; determining, by the processor, a second flow in a blood vessel based on scaling the first flow by a numerical factor from the first physiological state to a second physiological state, the second physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, wherein the second flow corresponds to the second physiological state of the patient that is different from the first physiological state of the patient; determining, by the processor, the hemodynamic pressure quantity based on the second flow; and reporting the hemodynamic pressure quantity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system for determining a hemodynamic pressure quantity, the system comprising:
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a processor; a non-transitory memory coupled to the processor; first logic stored in the memory and executable by the processor to cause the processor to acquire angiography data from a patient at a first physiological state of the patient, the first physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, the angiography data comprising x-ray angiography data, magnetic resonance angiography data, and/or computed tomographic angiography data; second logic stored in the memory and executable by the processor to cause the processor to determine a flow as a scaled flow based on the angiography data, wherein the flow corresponds to a second physiological state of the patient that is different from the first physiological state of the patient, the second physiological state comprising a state of hyperemia, a state of rest, or a state of exercise; third logic stored in the memory and executable by the processor to cause the processor to determine a change in pressure in a blood vessel of the patient based on the angiography data; fourth logic stored in the memory and executable by the processor to cause the processor to determine the hemodynamic pressure quantity based on the flow and/or the change in pressure; and a display configured to output the hemodynamic pressure quantity. - View Dependent Claims (15, 16, 17)
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18. A non-transitory computer readable storage medium having stored therein data representing instructions executable by a programmed processor for determining a hemodynamic pressure quantity, the storage medium comprising instructions for:
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acquiring angiography data from a patient at a first physiological state of the patient, the first physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, the angiography data comprising x-ray angiography data, magnetic resonance angiography data, and/or computed tomographic angiography data; determining a flow based on the angiography data, wherein the flow corresponds to a second physiological state of the patient that is different from the first physiological state of the patient, the second physiological state comprising a state of hyperemia, a state of rest, or a state of exercise, the flow being derived by scaling another flow determined for the first physiological state; determining a change in pressure in a blood vessel of the patient based on the angiography data; determining the hemodynamic pressure quantity based on the flow and/or the change in pressure; and outputting the hemodynamic pressure quantity.
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Specification