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Droplet creation techniques

  • US 9,839,911 B2
  • Filed: 05/08/2015
  • Issued: 12/12/2017
  • Est. Priority Date: 10/27/2009
  • Status: Active Grant
First Claim
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1. An article, comprising:

  • a first fluid containing a plurality of droplets, at least some of which have distinguishable compositions; and

    a device comprising;

    a microfluidic channel containing the first fluid flowing toward an intersection, a first channel portion upstream of the intersection, and a second channel portion downstream of the intersection;

    two intersecting channels that intersect the microfluidic channel at the intersection, the intersecting channels containing a second fluid flowing toward the intersection; and

    the second channel portion downstream of the intersection contains a plurality of divided droplets produced from a droplet upstream of the intersection,wherein the device produces divided droplets in the microfluidic channel from the plurality of droplets contained within the first fluid upon intersection of the first fluid containing the plurality of droplets with the second fluid, the produced divided droplets having a distribution of diameters such that no more than about 5% of the divided droplets have a diameter greater than about 10% different than the average diameter of the divided droplets.

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