Compositions, kits, and methods to induce acquired cytoresistance using stress protein inducers
First Claim
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1. A method of protecting an organ of a human patient from injury based on a scheduled insult comprising administering to the organ a therapeutically effective amount of (i) iron sucrose;
- and (ii) a protoporphyrin, the therapeutically effective amount being administered before the scheduled insult to the organ occurs, wherein the administering protects the organ from the injury without causing injury to the organ.
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Abstract
The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin B12 and, optionally, agents that impact heme protein metabolism.
8 Citations
14 Claims
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1. A method of protecting an organ of a human patient from injury based on a scheduled insult comprising administering to the organ a therapeutically effective amount of (i) iron sucrose;
- and (ii) a protoporphyrin, the therapeutically effective amount being administered before the scheduled insult to the organ occurs, wherein the administering protects the organ from the injury without causing injury to the organ.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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