Method for determination of analyte concentrations and related apparatus
First Claim
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1. A method for determining an analyte in a sample comprising the steps of:
- introducing a sample to be evaluated into an electrochemical test strip having working and counter electrodes;
applying a potential between the electrodes sufficient to generate a diffusion-limited current when analyte is present in the sample;
dynamically determining a time, tpeak, as the time when diffusion limiting current at the counter electrode is established;
sampling the current value at a time, tmeas, wherein tmeas is a multiple of tpeak, andgenerating an indication of analyte in the sample based on the sampled current value at time tmeas.
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Abstract
A method is provided for determining analyte concentrations, for example glucose concentrations, that utilizes a dynamic determination of the appropriate time for making a glucose measurement, for example when a current versus time curve substantially conforms to a Cottrell decay, or when the current is established in a plateau region. Dynamic determination of the time to take the measurement allows each strip to operate in the shortest appropriate time frame, thereby avoiding using an average measurement time that may be longer than necessary for some strips and too short for others.
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Citations
8 Claims
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1. A method for determining an analyte in a sample comprising the steps of:
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introducing a sample to be evaluated into an electrochemical test strip having working and counter electrodes; applying a potential between the electrodes sufficient to generate a diffusion-limited current when analyte is present in the sample; dynamically determining a time, tpeak, as the time when diffusion limiting current at the counter electrode is established; sampling the current value at a time, tmeas, wherein tmeas is a multiple of tpeak, and generating an indication of analyte in the sample based on the sampled current value at time tmeas. - View Dependent Claims (2, 3, 4, 5)
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6. A method for determining an analyte in a sample comprising the steps of:
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introducing a sample to be evaluated into an electrochemical test strip having working and counter electrodes; applying a potential between the electrodes sufficient to generate a diffusion-limited current when analyte is present in the sample; dynamically determining a time, tpeak, as the time when diffusion limiting current at the counter electrode is established; sampling the current value at a time, tmeas, wherein tmeas is determined by adding a defined period of time to tpeak, and generating an indication of analyte in the sample based on the sampled current value at time tmeas. - View Dependent Claims (7, 8)
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Specification