Ophthalmic diagnosis support apparatus and ophthalmic diagnosis support method

• US 9,848,769 B2
• Filed: 07/25/2012
• Issued: 12/26/2017
• Est. Priority Date: 08/01/2011
• Status: Active Grant

• Current Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Original Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Inventors: Miyasa, Kazuhiro, Imamura, Hiroshi
• Primary Examiner(s): SCHWARTZ, JORDAN MARC
• Application Number:
  US14/122,265
• Publication Number:
  US 20140085606A1
• Time in Patent Office: 1,980 Days
• CPC Class Codes: A61B 3/0041 characterised by display arrangements
• CPC Class Codes: A61B 3/1005 for measuring distances inside the eye, e.g. thickness of the cornea A61B3/11 takes precedence
• CPC Class Codes: A61B 3/102 for optical coherence tomography [OCT]
• CPC Class Codes: A61B 3/12 for looking at the eye fundus, e.g. ophthalmoscopes A61B3/13 takes precedence
• CPC Class Codes: A61B 3/14 Arrangements specially adapted for eye photography apparatus or arrangements for taking photographs per se G03B
• CPC Class Codes: A61B 5/0037 Performing a preliminary scan, e.g. a prescan for identifying a region of interest
• CPC Class Codes: G06T 2207/10101 Optical tomography; Optical coherence tomography [OCT]
• CPC Class Codes: G06T 2207/30041 Eye; Retina; Ophthalmic
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G06V 10/255 Detecting or recognising potential candidate objects based on visual cues, e.g. shapes
• CPC Class Codes: G06V 40/19 Sensors therefor

Abstract

Provided is an ophthalmic diagnosis support apparatus which enables an operator to easily acquire a tomographic image suitable for detailed observation of a candidate lesion without spending time and effort to search for the candidate lesion. The ophthalmic diagnosis support apparatus includes an acquiring unit for acquiring a wide-range image of a fundus, a candidate lesion detection unit for detecting the candidate lesion on the fundus by analyzing the wide-range image, a calculating unit for determining a degree of abnormality of the candidate lesion based on a result of the detection of the candidate lesion, and an acquiring position setting unit for setting an acquiring position of the tomographic image of the fundus based on the degree of abnormality of the candidate lesion.

Claims

1. An apparatus comprising:

an acquiring unit configured to acquire a volume image of a retina;

a detection unit configured to detect a center of a macula lutea by analyzing the volume image;

a comparing unit configured to compare a thickness of the retina obtained from the volume image with a threshold value to obtain a difference as a degree of abnormality;

a determining unit configured to determine a portion where the difference obtained by the comparing unit is larger than the difference of another portion on the retina, the portion determined by the determining unit being a different portion from the center of the macula lutea; and

an acquiring position setting unit configured to set a single scan line for imaging and/or displaying a tomographic image of the retina, the single scan line passing through the portion determined by the determining unit and the center of the macula lutea.

2. An apparatus according to claim 1, wherein the acquiring position setting unit is configured to set, as an imaging position of the tomographic image of the retina, the single scan line.

3. An apparatus according to claim 1, wherein the acquiring position setting unit is configured to set, as a display position of the tomographic image of the retina, the single scan line.

4. An apparatus according to claim 1, wherein the single scan line is a line segment passing through a position of the maximum degree of abnormality and the center of the macula lutea.

6. A program for causing a computer to function as the apparatus according to claim 1.

7. A computer-readable medium having the program according to claim 6 stored thereon.

8. An apparatus according to claim 1, wherein the acquiring position setting unit is configured to set a plurality of scan lines of tomographic images of the retina,

wherein one of the plurality of the scan lines passes through the portion determined by the determining unit and the center of the macula lutea, and

wherein a tomographic image of another of the scan lines does not intersect with the tomographic image of the one of the acquiring positions.

9. An apparatus according to claim 1, further comprising:

a detection unit configured to detect a candidate lesion in the retina by analyzing the volume image,

wherein the comparing unit compares a thickness of the candidate lesion detected by the detection unit with the threshold value to obtain the difference as the degree of abnormality.

25. An apparatus according to claim 1, wherein the detection unit is capable of detecting the center of the macula lutea by using an anatomical feature that the center of the macula lutea is a dent area on a fundus.

26. An apparatus according to claim 25, wherein the detection unit detects, if the anatomical feature that the center of the macula lutea is the dent area on the fundus is not used for detecting the center of the macula lutea, the center of the macula lutea by using anatomical features that (a) a retinal blood vessel does not exist at the center of the macula lutea and (b) a nerve fiber layer does not exist at the center of the macula lutea.

5. A method comprising:

acquiring a volume image of a retina;

detecting a center of a macula lutea by analyzing the volume image;

comparing a thickness of the retina obtained from the volume image with a threshold value to obtain a difference as a degree of abnormality;

determining a portion where the difference obtained in the comparing step is larger than the difference of another portion on the retina, the determined portion being a different portion from the center of the macula lutea; and

setting a single scan line for imaging and/or displaying a tomographic image of the retina, the single scan line passing through the determined portion and the center of the macula lutea.

10. An apparatus comprising:

an acquiring unit configured to acquire a volume image of a retina;

detection unit configured to detect a center of a macula lutea by analyzing the volume image;

a comparing unit configured to compare a thickness of the retina obtained from the volume image with a threshold value to obtain a difference as a degree of abnormality;

a determining unit configured to determine a portion where the difference obtained by the comparing unit is larger than the difference of another portion on the retina, the portion determined by the determining unit being a different portion from the center of the macula lutea; and

an acquiring position setting unit configured to set a single scan line for imaging a tomographic image of the retina, the single scan line passing through the portion determined by the determining unit and the center of the macula lutea.

12. An apparatus according to claim 10, wherein the single scan line is a line segment passing through a position of the maximum degree of abnormality and the center of the macula lutea.

13. A program for causing a computer to function as the apparatus according to claim 10.

14. A computer-readable medium having the program according to claim 13 stored thereon.

15. An apparatus according to claim 10, wherein the acquiring position setting unit is configured to set a plurality of scan lines of tomographic images of the retina,

wherein one of the plurality of the scan lines passes through the portion determined by the determining unit and the center of the macula lutea, and

wherein a tomographic image of another of the scan lines does not intersect with the tomographic image of the one of the acquiring positions.

16. An apparatus according to claim 10, further comprising:

a detection unit configured to detect a candidate lesion in the retina by analyzing the volume image,

wherein the comparing unit compares a thickness of the candidate lesion detected by the detection unit with the threshold value to obtain the difference as the degree of abnormality.

27. An apparatus according to claim 10, wherein the detection unit is capable of detecting the center of the macula lutea by using an anatomical feature that the center of the macula lutea is a dent area on a fundus.

28. An apparatus according to claim 27, wherein the detection unit detects, if the anatomical feature that the center of the macula lutea is the dent area on the fundus is not used for detecting the center of the macula lutea, the center of the macula lutea by using anatomical features that (a) a retinal blood vessel does not exist at the center of the macula lutea and (b) a nerve fiber layer does not exist at the center of the macula lutea.

11. A method comprising:

acquiring a volume image of a retina;

detecting a center of a macula lutea by analyzing the volume image;

comparing a thickness of the retina obtained from the volume image with a threshold value to obtain a difference as a degree of abnormality;

determining a portion where the difference obtained in the comparing step is larger than the difference of another portion on the retina, the determined portion being a different portion from the center of the macula lutea; and

setting a single scan line for imaging a tomographic image of the retina, the single scan line passing through the determined portion and the center of the macula lutea.

17. An apparatus comprising:

an acquiring unit configured to acquire a volume image of a retina;

a detection unit configured to detect a center of a macula lutea by analyzing the volume image;

a comparing unit configured to compare a thickness of the retina obtained from the volume image with a threshold value to obtain a difference as a degree of abnormality;

a determining unit configured to determine a portion where the difference obtained by the comparing unit is larger than the difference of another portion on the retina, the portion determined by the determining unit being a different portion from the macula lutea; and

an acquiring position setting unit configured to set a single scan line for imaging and/or displaying a tomographic image of the retina, wherein a position and a direction of the single scan line is set based on the portion determined by the determining unit and the center of the macula lutea.

18. An apparatus according to claim 17, wherein the acquiring position setting unit is configured to set, as an imaging position of the tomographic image of the retina, the single scan line.

19. An apparatus according to claim 17, wherein the acquiring position setting unit is configured to set, as a display position of the tomographic image of the retina, the single scan line.

20. An apparatus according to claim 17, wherein the single scan line is a line segment passing through a position of the maximum degree of abnormality and the center of the macula lutea.

21. An apparatus according to claim 17, further comprising:

a fundus image acquiring unit configured to acquire a fundus image; and

a display control unit configured to display, on a display screen, the single scan line superimposed on the fundus image.

22. A program for causing a computer to function as the apparatus according to claim 17.

23. A computer-readable medium having the program according to claim 22 stored thereon.

29. An apparatus according to claim 17, wherein the detection unit is capable of detecting the center of the macula lutea by using the anatomical feature that the center of the macula lutea is a dent area on a fundus.

30. An apparatus according to claim 29, wherein the detection unit detects, if the anatomical feature that the center of the macula lutea is the dent area on the fundus is not used for detecting the center of the macula lutea, the center of the macula lutea by using anatomical features that (a) a retinal blood vessel does not exist at the center of the macula lutea and (b) a nerve fiber layer does not exist at the center of the macula lutea.

24. A method comprising:

acquiring a volume image of a retina;

detecting a center of a macula lutea by analyzing the volume image;

comparing a thickness of the retina obtained from the volume image with a threshold value to obtain a difference as a degree of abnormality;

determining a portion where the difference obtained in the comparing step is larger than the difference of another portion on the retina, the determined portion being a different portion from the macula lutea; and

setting a single scan line for imaging and/or displaying a tomographic image of the retina,

wherein a position and a direction of the single scan line is set based on the determined portion and the center of the macula lutea.