Neural stimulation system to deliver different pulse types

• US 9,849,285 B2
• Filed: 01/18/2016
• Issued: 12/26/2017
• Est. Priority Date: 07/20/2007
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Lee, Dongchul, Moffitt, Michael A., Gillespie, Christopher Ewan, Bradley, Kerry
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US14/997,692
• Publication Number:
  US 20160129247A1
• Time in Patent Office: 708 Days
• Field of Search: None
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36038 Cochlear stimulation
• CPC Class Codes: A61N 1/36046 of the eye
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36062 Spinal stimulation
• CPC Class Codes: A61N 1/3614 based on impedance measurement
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: A61N 1/378 Electrical supply
• CPC Class Codes: A61N 1/3787 from an external energy source
• CPC Class Codes: A61N 1/3906 characterised by the form of the shockwave

Abstract

A method, electrical tissue stimulation system, and programmer for providing therapy to a patient are provided. Electrodes are placed adjacent tissue (e.g., spinal cord tissue) of the patient, electrical stimulation energy is delivered from the electrodes to the tissue in accordance with a defined waveform, and a pulse shape of the defined waveform is modified, thereby changing the characteristics of the electrical stimulation energy delivered from the electrode(s) to the tissue. The pulse shape may be modified by selecting one of a plurality of different pulse shape types or by adjusting a time constant of the pulse shape.

Claims

1. A system, comprising:

one or more electrical terminals configured to be coupled to one or more stimulation leads that include a plurality of electrodes;

output stimulation circuitry configured to output electrical stimulation energy as a temporal series of electrical pulses to the one or more electrical terminals in accordance with a set of stimulation parameters for a defined pulsed electrical waveform, wherein the stimulation parameters include;

electrode combinations to define which of the plurality of electrodes are anodes, cathodes or off; and

electrical pulse parameters to define pulse amplitudes, pulse durations and pulse shapes defined by pulse shape types, wherein a single temporal series of electrical pulses includes a variety of pulse shape types; and

control circuitry including memory with parameters stored therein defining a plurality of pulse shape types, wherein the control circuitry is configured to use the parameters stored in the memory to provide the variety of pulse shape types in the single temporal series of electrical pulses.

2. The system of claim 1, further comprising a user interface configured to present the plurality of pulse shape types to a user for selection by the user to program the parameters stored in the memory.

3. The system of claim 1, wherein the different pulse shape types comprise a square pulse and an exponential pulse.

4. The system of claim 1, wherein the different pulse shape types comprise at least two pulse types selected from the group of pulse types consisting of a square pulse, an exponential pulse, a logarithmic pulse, a ramped pulse, and a trapezoidal pulse.

5. The system of claim 1, wherein the different pulse shape types comprise a negatively sloping pulse and a positively sloping pulse.

6. The system of claim 5, wherein the negatively sloping pulse is a negatively sloping exponential pulse, and the positively sloping pulse is a positively sloping exponential pulse.

7. The system of claim 5, wherein the negatively sloping pulse is a negatively sloping linear ramp pulse, and the positively sloping pulse is a positively sloping linear ramp pulse.

8. The system of claim 1, wherein the control circuitry is configured for modifying the pulse shape by adjusting a time constant of the pulse shape.

9. The system of claim 1, wherein the control circuitry is configured for modifying the pulse shape and other pulse parameters of the defined waveform independent of each other.

10. The system of claim 1, wherein the control circuitry is configured for modifying the pulse shape and at least one other pulse parameter dependent on each other to maintain a substantially uniform charge of the electrical stimulation energy.

11. The system of claim 1, further comprising monitoring circuitry configured for measuring one or more electrical characteristics of the tissue, wherein the control circuitry is configured for modifying the pulse shape based on the measured one or more electrical characteristics, wherein the control circuitry is configured for modifying the pulse shape in response to a change in the measured one or more electrical characteristics.

12. The system of claim 1, wherein the output stimulation circuitry comprises a plurality of different analog shaping circuits, and the control circuitry is configured for modifying the pulse shape by selecting one of the different analog shaping circuits.

13. The system of claim 1, wherein the control circuitry is configured for modifying the pulse shape by adjusting a characteristic of at least one analog electrical component in the output stimulation circuitry.

14. The system of claim 1, wherein the pulsed waveform is formed of a stepwise function of amplitude levels or sub-pulse durations, and wherein the control circuitry is configured for modifying the pulse shape by adjusting the amplitude levels or sub-pulse durations.

15. The system of claim 1, further comprising a stimulation lead carrying at least one electrode electrically coupled to the one or more electrical terminals.

16. A system, comprising:

an implantable system and an external system configured to program the implantable system;

the implantable system including an implantable case containing control circuitry, output stimulation circuitry, and one or more electrical terminals configured to be electrically connected to one or more stimulation leads that include a plurality of electrodes, wherein;

the output stimulation circuitry is configured to output electrical stimulation energy as a temporal series of electrical pulses to the one or more electrical terminals in accordance with a set of stimulation parameters for a defined pulsed electrical waveform,

the stimulation parameters include;

electrode combinations to define which of the plurality of electrodes that are anodes, cathodes or off; and

electrical pulse parameters to define pulse amplitudes, pulse durations and pulse shapes defined by pulse shape types, wherein a single temporal series of electrical pulses includes a variety of pulse types; and

the control circuitry includes memory with parameters stored therein defining a plurality of pulse shape types, wherein the control circuitry is configured to use the parameters stored in the memory to provide the variety of pulse shape types in the single temporal series of electrical pulses; and

the external system including a user interface configured to present the plurality of pulse shape types to a user for selection by the user to program the single temporal series of electrical pulses.

17. The system of claim 16, wherein the output stimulation circuitry comprises a plurality of different analog shaping circuits, and the control circuitry is configured to provide the variety of pulse shape types by selecting different analog shaping circuits.

18. The system of claim 16, wherein the control circuitry is configured to provide the variety of pulse shape types by adjusting a characteristic of at least one analog electrical component in the output stimulation circuitry.

19. The system of claim 16, wherein the pulsed waveform is formed of a stepwise function of amplitude levels or sub-pulse durations, and wherein the control circuitry is configured to provide the variety of pulse shape types by adjusting the amplitude levels or sub-pulse durations.

20. The system of claim 16, wherein the different pulse shape types comprise at least two pulse types selected from the group of pulse types consisting of a square pulse, an exponential pulse, a logarithmic pulse, a ramped pulse, and a trapezoidal pulse.