Spirometry-based personal health risk assessment device

• US 9,861,299 B1
• Filed: 08/12/2011
• Issued: 01/09/2018
• Est. Priority Date: 08/12/2011
• Status: Active Grant

• Current Assignee: Jones Medical Instrument Company
• Original Assignee: Jones Medical Instrument Company
• Inventors: Jones, William, Jones, Scott, Heeb, Louis J.
• Primary Examiner(s): Agahi, Puya
• Application Number:
  US13/209,316
• Time in Patent Office: 2,342 Days
• Field of Search: 600529, 600537, 600538, 600543
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/0878 using temperature sensing means
• CPC Class Codes: A61B 5/097 Devices for facilitating collection of breath or for directing breath into or through measuring devices
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

A health risk assessment device includes a mouthpiece, a flow path in fluid communication with the mouthpiece, a sensor disposed in the flow path and configured to generate a representation of a spirometric parameter of air flow in the flow path exhaled by a user through the mouthpiece, a user interface configured to allow the user to provide user profile data including smoking history data, and a processor coupled to the sensor and the user interface and configured to determine an output indicative of a risk that the user develops a respiratory, cardiopulmonary, or cardiovascular disease based on the spirometric parameter representation and the smoking history data.

Claims

1. A health risk assessment device comprising:

a mouthpiece;

a flow path in fluid communication with the mouthpiece;

a sensor disposed in the flow path and configured to generate a signal representative of a dynamically changing air flow in the flow path provided by a user through the mouthpiece;

a user interface configured to allow the user to provide an age of the user; and

a processor coupled to the sensor and configured to;

digitally filter the signal representative of the dynamically changing air flow to generate flow data for the dynamically changing air flow;

implement a test to evaluate the flow data, the test determining time elapsed to reach peak flow;

evaluate the flow data to validate that the dynamically changing air flow is qualified for spirometric parametric determination based on the test;

integrate the flow data to determine a volume for the dynamically changing air flow; and

determine spirometric data for the air flow based on the volume;

wherein the processor is further coupled to the user interface and configured to determine an output specifying a lung age gap based on the spirometric data and the age of the user.

2. The health risk assessment device of claim 1, wherein the spirometric data is representative of forced expiratory volume in one second (FEV1).

3. The health risk assessment device of claim 1, wherein the sensor is configured to capture a dynamic measurement of exhaust air velocity in the flow path.

4. The health risk assessment device of claim 1, further comprising a housing in which the flow path is disposed, and wherein the mouthpiece is integrally formed with the housing.

5. The health risk assessment device of claim 1, further comprising a flow chamber in which the sensor is disposed, wherein the mouthpiece and the flow chamber are non-separable from one another.

6. The health risk assessment device of claim 1, wherein the sensor comprises a thermistor.

7. The health risk assessment device of claim 1, wherein:

the user interface is further configured to allow the user to provide user profile data including smoking history data; and

the processor is further configured to determine a further output specifying a risk that the user develops a disease based on the spirometric data and the smoking history data.

31. The health risk assessment device of claim 1, wherein the processor is further configured to reject sensor data based on whether the representation fails the test, and provide an indication via the user interface as to why the data was rejected.

8. A health risk assessment device comprising:

a mouthpiece;

a flow path in fluid communication with the mouthpiece;

a sensor disposed in the flow path and configured to generate a signal representative of a dynamically changing air flow in the flow path provided by a user through the mouthpiece;

a user interface configured to allow the user to provide user profile data including smoking history data and an age of the user; and

a processor coupled to the sensor and configured to;

digitally filter the signal representative of the dynamically changing air flow to generate flow data for the dynamically changing air flow;

implement a test to evaluate the flow data, the test determining time elapsed from zero flow to ramp-up;

evaluate the flow data to validate that the dynamically changing air flow is qualified for spirometric parametric determination based on the test;

integrate the flow data to determine a volume for the dynamically changing air flow; and

determine spirometric data for the air flow based on the volume;

wherein the processor is further coupled to the user interface and configured to determine a plurality of outputs based on the spirometric data and the user profile data and specifying a plurality of health risks of the user, respectively, the plurality of health risks comprising a first health risk for which the respective output specifies a lung age gap, and a second health risk for which the respective output specifies a likelihood that the user develops chronic obstructive pulmonary disease (COPD).

9. The health risk assessment device of claim 8, further comprising a housing in which the flow path is disposed, and wherein the mouthpiece, the sensor, and the housing are non-separable from one another.

10. The health risk assessment device of claim 8, further comprising a flow chamber in which the sensor is disposed, wherein the mouthpiece and the flow chamber are non-separable from one another.

11. The health risk assessment device of claim 8, wherein the sensor is configured to capture a dynamic measurement of exhaust air velocity in the flow path.

12. The health risk assessment device of claim 8, wherein the sensor comprises a thermistor.

13. The health risk assessment device of claim 12, further comprising an air shield disposed along the flow path and configured to shield the thermistor from heat loss arising from air moving in one direction.

14. The health risk assessment device of claim 12, wherein the processor is configured to determine a velocity of the air flow based on a measurement of power provided to the thermistor to maintain the thermistor at a constant temperature.

15. The health risk assessment device of claim 12, wherein the thermistor is configured for operation at a temperature level at which the thermistor is insensitive to barometric and humidity variations.

16. The health risk assessment device of claim 8, wherein the flow path has differing inhalation and exhalation flow resistances.

17. The health risk assessment device of claim 8, wherein the sensor has a single-thermistor architecture.

18. The health risk assessment device of claim 8, wherein the processor is configured to implement an anti-aliasing decimation filter.

19. The health risk assessment device of claim 18, wherein the anti-aliasing decimation filter introduces zero phase shift.

20. The health risk assessment device of claim 8, further comprising an analog pre-filter coupled to the processor.

22. The health risk assessment device of claim 11, wherein the sensor is configured to capture a dynamic measurement of exhaust air velocity in the flow path.

23. The health risk assessment device of claim 11, wherein the housing and the mouthpiece are integrally formed.

24. The health risk assessment device of claim 11, further comprising a flow chamber in which the sensor is disposed, wherein the mouthpiece and the flow chamber are non-separable from one another.

25. The health risk assessment device of claim 11, wherein the sensor has a single-thermistor architecture.

26. The health risk assessment device of claim 11, wherein the flow path has differing inhalation and exhalation flow resistances.

27. The health risk assessment device of claim 11, further comprising an air shield disposed along the flow path and configured to shield the thermistor from heat loss arising from air moving in one direction.

28. The health risk assessment device of claim 11, wherein the processor is configured to determine a velocity of the air flow based on a measurement of power provided to the thermistor to maintain the thermistor at a constant temperature.

29. The health risk assessment device of claim 11, wherein the thermistor is configured for operation at a temperature level at which the thermistor is insensitive to barometric and humidity variations.

30. The health risk assessment device of claim 11, wherein the thermistor is configured as a small-size thermistor.

32. The health risk assessment device of claim 18, wherein the processor is further configured to reject sensor data based on whether the representation fails the test, and provide an indication via the user interface as to why the data was rejected.

21. A health risk assessment device comprising:

a mouthpiece;

a housing inseparably attached to the mouthpiece;

a flow path disposed in the housing and in fluid communication with the mouthpiece;

a sensor disposed in the flow path and configured to generate a signal representative of a dynamically changing air flow in the flow path provided by a user through the mouthpiece;

a user interface configured to allow the user to provide user profile data; and

a processor coupled to the sensor and configured to;

digitally filter the signal representative of the dynamically changing air flow to generate flow data for the dynamically changing air flow;

implement a test to evaluate the flow data, the test determining time elapsed to reach peak flow;

evaluate the flow data to validate that the dynamically changing air flow is qualified for spirometric parametric determination based on the test;

integrate the flow data to determine a volume for the dynamically changing air flow; and

determine spirometric data for the air flow based on the volume;

wherein the processor is further coupled to the user interface and configured to determine an output specifying a lung age gap based on the spirometric data and the user profile data; and

wherein the sensor comprises a thermistor.

33. The health risk assessment device of claim 21, wherein the processor is further configured to reject sensor data based on whether the representation fails the test, and provide an indication via the user interface as to why the data was rejected.