Methods and systems for determining regional blood oxygen saturation
First Claim
1. A system for determining regional blood oxygen saturation (rSO2) of a subject comprising:
- an oximeter configured for;
generating a light drive signal configured to cause one or more light sources to emit a plurality of light signals, wherein the plurality of light signals corresponds to a plurality of wavelengths of light;
receiving a first plurality of light signals that have been attenuated by a first region of the subject, wherein the first plurality of light signals corresponds to the plurality of wavelengths of light;
determining a first plurality of absorption values corresponding to the first region of the subject, wherein each of the first plurality of absorption values corresponds to a respective one of the plurality of wavelengths of light;
receiving a second plurality of light signals that have been attenuated by a second region of the subject, wherein the second plurality of light signals corresponds to the plurality of wavelengths of light;
determining a second plurality of absorption values corresponding to the second region of the subject, wherein each of the second plurality of absorption values corresponds to a respective one of the plurality of wavelengths of light;
determining a difference between each of the first plurality of absorption values and a respective one of the second plurality of absorption values to generate a plurality of differential absorption values corresponding, respectively, to the plurality of wavelengths of light;
receiving reference sets of absorption data, wherein each of the reference sets corresponds to a different rSO2 value and comprises expected absorption values for each of the plurality of wavelengths of light;
comparing the plurality of differential absorption values to the expected absorption values of the reference sets;
determining a best fit reference set of the reference sets based on the comparison; and
determining the rSO2 of the subject based on the determined best fit reference set.
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Abstract
Methods and systems are presented for determining regional blood oxygen saturation (rSO2) of a subject. Differential absorption values may be determined based on received first and second light signals corresponding to light attenuated by respective first and second regions of the subject. Reference absorption curves are received, each associated with an rSO2 value and containing expected absorption values. The differential absorption values are compared with the expected absorption values to determine a best fit reference absorption curve. An rSO2 value is determined based on the best fit reference absorption curve. An rSO2 value may also be determined based on a combination of two or more rSO2 estimates. The rSO2 estimates are determined based on two or more pairs of the differential absorption values. The differential absorption values are determined based on received first and second lights signals corresponding to three or more wavelengths of light.
68 Citations
11 Claims
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1. A system for determining regional blood oxygen saturation (rSO2) of a subject comprising:
an oximeter configured for; generating a light drive signal configured to cause one or more light sources to emit a plurality of light signals, wherein the plurality of light signals corresponds to a plurality of wavelengths of light; receiving a first plurality of light signals that have been attenuated by a first region of the subject, wherein the first plurality of light signals corresponds to the plurality of wavelengths of light; determining a first plurality of absorption values corresponding to the first region of the subject, wherein each of the first plurality of absorption values corresponds to a respective one of the plurality of wavelengths of light; receiving a second plurality of light signals that have been attenuated by a second region of the subject, wherein the second plurality of light signals corresponds to the plurality of wavelengths of light; determining a second plurality of absorption values corresponding to the second region of the subject, wherein each of the second plurality of absorption values corresponds to a respective one of the plurality of wavelengths of light; determining a difference between each of the first plurality of absorption values and a respective one of the second plurality of absorption values to generate a plurality of differential absorption values corresponding, respectively, to the plurality of wavelengths of light; receiving reference sets of absorption data, wherein each of the reference sets corresponds to a different rSO2 value and comprises expected absorption values for each of the plurality of wavelengths of light; comparing the plurality of differential absorption values to the expected absorption values of the reference sets; determining a best fit reference set of the reference sets based on the comparison; and determining the rSO2 of the subject based on the determined best fit reference set. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
Specification