Drug-delivery pumps and methods of manufacture
First Claim
Patent Images
1. An implantable ophthalmic pump comprising:
- a drug pump;
a glaucoma drainage device;
a first group of one or more cannulas configured for fluidly coupling the drug pump to a first treatment site in a patient; and
a second group of one or more cannulas configured for fluidly coupling the glaucoma drainage device to a second treatment site in the patient,wherein the glaucoma drainage device comprises a portion of a surface area above the drug pump.
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Abstract
Embodiments of method of manufacturing an implantable pump, including providing an upper layer comprising a dome structure for housing a drug chamber and a cannula in fluid communication with the drug chamber, providing a middle deflection layer adjacent the drug chamber, providing a bottom layer comprising electrolysis electrodes, and bonding the upper layer, middle deflection layer, and bottom layer to form the pump.
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Citations
29 Claims
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1. An implantable ophthalmic pump comprising:
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a drug pump; a glaucoma drainage device; a first group of one or more cannulas configured for fluidly coupling the drug pump to a first treatment site in a patient; and a second group of one or more cannulas configured for fluidly coupling the glaucoma drainage device to a second treatment site in the patient, wherein the glaucoma drainage device comprises a portion of a surface area above the drug pump. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An implantable ophthalmic pump comprising:
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a drug pump; a glaucoma drainage device; a first group of one or more cannulas configured for fluidly coupling the drug pump to a first treatment site in a patient; and a second group of one or more cannulas configured for fluidly coupling the glaucoma drainage device to a second treatment site in the patient, wherein the glaucoma drainage device comprises an end plate disposed over a shell of the implantable ophthalmic pump. - View Dependent Claims (10, 11, 12)
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13. An implantable ophthalmic pump comprising:
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a drug pump; a glaucoma drainage device; a first group of one or more cannulas configured for fluidly coupling the drug pump to a first treatment site in a patient; and a second group of one or more cannulas configured for fluidly coupling the glaucoma drainage device to a second treatment site in the patient, wherein the glaucoma drainage device comprises an end plate integrated into a shell of the implantable ophthalmic pump. - View Dependent Claims (14, 15, 16)
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17. An implantable ophthalmic pump comprising:
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a drug pump; a glaucoma drainage device; a first group of one or more cannulas configured for fluidly coupling the drug pump to a first treatment site in a patient; a second group of one or more cannulas configured for fluidly coupling the glaucoma drainage device to a second treatment site in the patient; and a single cannula sleeve surrounding the first and second groups of one or more cannulas. - View Dependent Claims (18, 19, 20)
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21. A method of simultaneously administering a drug and dissipating aqueous fluid, the method comprising the steps of:
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providing a pump comprising an electrolysis chamber and a drug chamber; providing a glaucoma drainage device comprising a portion of a surface area above the pump; activating the electrolysis chamber to dispense a volume of drug from the drug chamber to a treatment site, the drug chamber decreasing in volume as the drug is dispensed therefrom; deactivating the electrolysis chamber to stop dispensing the drug, whereby the electrolysis chamber decreases in volume; and providing a fluidic pathway to conduct a portion of the dispensed drug and aqueous fluid from the treatment site to the glaucoma drainage device when an intraocular pressure exceeds a predetermined limit. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29)
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Specification