Medical treatment system and methods using a plurality of fluid lines

• US 9,861,732 B2
• Filed: 11/02/2012
• Issued: 01/09/2018
• Est. Priority Date: 11/04/2011
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Scarpaci, Jacob W., Bryant, Jr., Robert J., Spencer, Geoffrey P., Hibbard, David J., Dale, James D., Kerwin, John M., Coll, Andrew S., Beavers, David A., McGill, David W., Helmore, Simon C.
• Primary Examiner(s): Hayman, Imani
• Application Number:
  US13/667,679
• Publication Number:
  US 20130165847A1
• Time in Patent Office: 1,894 Days
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/1664 with temperature control
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/282 Operational modes
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 2205/122 using evacuated interfaces to enhance contact
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/15 Detection of leaks
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/3327 Measuring
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/36 related to heating or cooling
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2205/8212 with means or measures taken for minimising energy consumption
• CPC Class Codes: A61M 2210/1017 : Peritoneal cavity
• CPC Class Codes: A61M 60/113 : in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: F04B 43/02 : having plate-like flexible members, e.g. diaphragms F04B43/14 takes precedence
• CPC Class Codes: F16L 53/00 : Heating of pipes or pipe systems; Cooling of pipes or pipe systems
• CPC Class Codes: F17D 1/00 : Pipe-line systems conveying articles or materials through a pipe- line by means of a fluid carrier B65G51/00, B65G53/00; liquids B67D; special devices for transferring liquids from bulk storage containers into vehicles or boats or vice versa, e.g. loading or unloading vehicles or portable containers B67D7/00; conveying material which has been excavated by a dredger or soil shifter through a pipe-line E02F7/10; sewer pipe-line systems E03F3/00; thermal insulation of pipe-lines F16L59/00; central heating systems F24D
• CPC Class Codes: H05B 1/025 : For medical applications
• CPC Class Codes: Y02E 60/10 : Energy storage using batteries
• CPC Class Codes: Y10T 137/6416 : With heating or cooling of the system
• CPC Class Codes: Y10T 137/85978 : With pump

Abstract

A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. A fluid trap of a peritoneal dialysis cycler may have a valved connection to a vacuum source or a positive pressure source. The fluid trap can be connected to the vacuum source in order to sealingly engage a flexible membrane of a pumping cassette to a control surface of the cycler during a therapy. Any fluid entering a space between the membrane and control surface can be drawn away and collected in the fluid trap. The fluid trap alternatively can be connected to a positive pressure source in order to aid in separating the membrane from the control surface to facilitate removal of the pumping cassette from the cycler. The fluid trap may include a liquid detection sensor.

Claims

1. A dialysis system comprising:

a pumping cassette having a generally planar body and a first flexible membrane on a side of the cassette having a pumping chamber portion overlying a pumping chamber on the cassette; and

a cycler having a control surface including a second flexible membrane having a movable portion arranged to contact and mate with the pumping chamber portion of the first flexible membrane, the cycler being arranged to control pneumatic pressure on a side of the movable portion of the second flexible membrane to move the movable portion of the second flexible membrane while mated with the pumping chamber portion of the first flexible membrane and thereby to move the pumping chamber portion of the first flexible membrane to cause fluid flow in the pumping chamber, the cycler further including at least one port at the control surface arranged to apply vacuum to remove fluid from a space between the pumping chamber portion of the first flexible membrane and the movable portion of the second flexible membrane to draw the pumping chamber portion and the movable portion toward each other such that the pumping chamber portion and the movable portion remain continuously mated and in contact so as to move with each other while causing fluid flow in the pumping chamber, the at least one port also arranged to introduce fluid into the space to move the first and second flexible membranes away from each other when separating the pumping cassette from the cycler;

the cycler further including a fluid trap in fluid communication with the at least one port and arranged to collect liquid that leaks from the pumping cassette and enters between the first flexible membrane and second flexible membrane, and in valved fluid communication with a positive pressure source and a negative pressure source for introduction or removal of said fluid with respect to said space;

wherein the pumping cassette including the first flexible membrane is separable from the cycler including the second flexible membrane, and the fluid trap includes a liquid detector.

2. The system of claim 1, wherein the at least one port includes a vacuum port arranged to selectively remove fluid in the space between the first and second flexible membranes, or introduce fluid into the space between the first and second flexible membranes.

3. The system of claim 2, wherein the fluid removed between the first and second flexible membranes includes air or liquid, and the fluid introduced into the space includes air.

4. The system of claim 1, wherein the control surface is a sheet of resilient polymer material.

5. The system of claim 1, wherein the control surface includes a plurality of movable portions, at least one movable portion being arranged to interact with the pumping chamber portion of the first flexible membrane overlying the pumping chamber, and at least one other movable portion being arranged to interact with another portion of the first flexible membrane to control flow in a channel of the pumping cassette.

6. The system of claim 1, wherein the control surface includes a plurality of ports to remove fluid in spaces between the first and second flexible membranes.

7. The system of claim 6, wherein the plurality of ports are also arranged to introduce fluid into the spaces between the first and second flexible membranes.

8. The system of claim 1, wherein the cycler includes a valved manifold to control flow of negative and positive pressure to the at least one port.

9. The system of claim 8, wherein the valved manifold is controllable to selectively provide negative pressure to the at least one port and positive pressure to the at least one port.

10. The system of claim 1, wherein the at least one port includes a hole in the second flexible membrane.

11. The system of claim 1, wherein introduction of fluid into the space between the first and second flexible membranes assists in separating the pumping cassette from the control surface of the cycler.

12. The system of claim 1, wherein the cycler includes a pressure delivery block that backs the control surface and includes control chambers or depressions in association with corresponding control regions of the control surface, each control chamber or depression being arranged to move the corresponding control region based on a fluid pressure in the control region or depression.

13. The system of claim 1 further comprising:

a base unit comprising the positive pressure source, the negative pressure source, a pressure distribution manifold, a pressure delivery block, and the control surface;

the pressure distribution manifold comprising valved channels between the positive and negative pressure sources and the pressure delivery block; and

the pressure delivery block comprising a depression in valved fluid communication with the positive and negative pressure sources;

wherein the second flexible membrane is positioned on the pressure delivery block so as to be interposed between the first flexible membrane of the cassette and the depression of the pressure delivery block;

wherein the pressure distribution manifold includes the fluid trap and is configured to provide a valved channel between the negative pressure source and the fluid trap, and

the pressure distribution manifold is configured to provide a valved channel between the positive pressure source and the fluid trap.

14. The system of claim 1, wherein the liquid detector comprises an electrical conductivity sensor.

15. The system of claim 1, further comprising a controller configured to receive a signal from the liquid detector and to generate an alert, close one or more liquid inlet valves of the pumping cassette, or cease a pumping operation of the pumping cassette upon detection of liquid in the fluid trap.

16. The system of claim 15, wherein the controller is configured to control a first valve to fluidically connect the negative pressure source with the at least one port during operation of the pumping cassette, and to control a second valve to fluidically connect the positive pressure source with the at least one port for separation of the pumping cassette from the cycler.

17. The system of claim 15, further comprising a pressure sensor in fluid communication with the fluid trap, the pressure sensor configured to provide pressure data to the controller.

18. A dialysis system comprising:

a pumping cassette having a generally planar body and a first flexible membrane on a side of the cassette having a pumping chamber portion overlying a pumping chamber on the cassette; and

a cycler having a control surface including a second flexible membrane having a movable portion arranged to contact and mate with the pumping chamber portion of the first flexible membrane, the cycler being arranged to control pneumatic pressure on a side of the movable portion of the second flexible membrane to move the movable portion of the second flexible membrane while mated with the pumping chamber portion of the first flexible membrane and thereby to move the pumping chamber portion of the first flexible membrane to cause fluid flow in the pumping chamber, the cycler further including at least one port at the control surface arranged to apply vacuum to remove fluid from a space between the pumping chamber portion of the first flexible membrane and the movable portion of the second flexible membrane to draw the pumping chamber portion and the movable portion toward each other such that the pumping chamber portion and the movable portion remain continuously mated and in contact as to move with each other while causing fluid flow in the pumping chamber, the at least one port also arranged to introduce fluid into the space to move the first and second flexible membranes away from each other when separating the pumping cassette from the cycler;

the cycler further including a fluid trap in fluid communication with the at least one port and arranged to collect liquid that leaks from the pumping cassette and enters between the first flexible membrane and second flexible membrane, and in valved fluid communication with a positive pressure source and a negative pressure source for introduction or removal of said fluid with respect to said space; and

a pressure sensor in fluid communication with the fluid trap,

wherein the pumping cassette including the first flexible membrane is separable from the cycler including the second flexible membrane.

19. The dialysis system of claim 18, wherein the fluid trap includes a liquid detector.

20. The dialysis system of claim 19, wherein the liquid detector comprises an electrical conductivity sensor.

21. The dialysis system of claim 20, wherein the controller is configured to receive a signal from the liquid detector and to generate an alert, close one or more liquid inlet valves of the pumping cassette, or cease a pumping operation of the pumping cassette upon detection of liquid in the fluid trap.

22. The dialysis system of claim 21, wherein the controller is configured to control a first valve to fluidically connect the negative pressure source with the at least one port during operation of the pumping cassette, and to control a second valve to fluidically connect the positive pressure source with the at least one port for separation of the pumping cassette from the cycler.