Optics cup with curved bottom

• US 9,862,920 B2
• Filed: 12/11/2013
• Issued: 01/09/2018
• Est. Priority Date: 12/11/2012
• Status: Active Grant

• Current Assignee: Pocared Diagnostics Ltd.
• Original Assignee: Pocared Diagnostics Ltd.
• Inventors: Ingber, Gal, Rogers, Martha J.
• Primary Examiner(s): Hurst, Jonathan
• Application Number:
  US14/102,742
• Publication Number:
  US 20140170740A1
• Time in Patent Office: 1,490 Days
• Field of Search: 4352887
• CPC Class Codes: B01L 2300/0809 rectangular shaped
• CPC Class Codes: B01L 2300/0851 Bottom walls
• CPC Class Codes: B01L 3/508 rigid containers not provided for above
• CPC Class Codes: C12M 41/36 of biomass, e.g. colony counters or by turbidity measurements electrooptical investigation of individual particles G01N15/14, flow cytometers G01N15/1404
• CPC Class Codes: G01N 2021/0382 Frustoconical, tapered cell
• CPC Class Codes: G01N 2021/6469 Cavity, e.g. ellipsoid
• CPC Class Codes: G01N 2021/6482 Sample cells, cuvettes
• CPC Class Codes: G01N 2035/0436 with pre-packaged reagents, i.e. test-packs
• CPC Class Codes: G01N 21/0303 Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment G01N21/031 - G01N21/15 take precedence
• CPC Class Codes: G01N 2201/0655 Hemispheres

Abstract

The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria, in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optics cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light. The system may utilize the disposable cartridge in the sample processor and the optics cup or cuvette in the optical analyzer, wherein the optics cup also has a floor in the shape of an inverted arch.

Claims

1. An optics cup for holding a biological sample for use in an optical analysis comprising:

a generally rectangular-shaped container adapted to contain the biological sample, said container including a pair of side walls having a longitudinal axis therebetween, a first end wall, and a second end wall spaced apart from the first end wall, and a floor,

said container having a top rectangular opening for receiving the biological sample and a lower tapered area extending from the first end wall in an inwardly and downwardly direction relative to the rectangular opening,

wherein the tapered area extends downwardly to the floor,

wherein the floor has the shape of an inverted arch extending along the entire length of the floor,

wherein the inverted arch is symmetric about and uniform along the longitudinal axis and the arch is curved,

wherein a portion of the container along at least the tapered area is reflective for reflecting illumination introduced into the top opening and for light collection to enhance optical analysis of the biological sample, and

wherein the arch is oriented such that the light inside the illuminated cup traveling away from an optical collection cone will be reflected to collection points along the longitudinal axis.

2. The optics cup as claimed in claim 1, wherein a surface of the container at least along the tapered area is coated with a layer of reflective material for light collection.

3. The optics cup as claimed in claim 2, wherein the reflective material is a wet ribbon liner.

4. The optics cup according to claim 3, wherein the wet ribbon liner is fastened to a flange of the rectangular opening of the container through a crimping process.

5. The optics cup according to claim 3, wherein the wet ribbon liner is secured to the flange of the rectangular opening of the container by at least a one-way retention tab.

6. The optics cup according to claim 3, wherein the ribbon liner is secured to the flange of the rectangular opening of the container by at least a heat staked pin.

7. The optics cup according to claim 3, wherein the container further includes a snap mechanism and wherein the wet ribbon liner is secured to the container by the snap mechanism.

8. The optics cup according to claim 1, wherein the cup is an injection molded cup and made of a leaching resistance material for minimizing the amount of contaminants leached out of the biological sample.

9. The optics cup according to claim 2, wherein the layer of reflective material is aluminum and is coated through a process selected from the group consisting of a vacuum metallization process and an electroplating process.

10. The optics cup as claimed in claim 1, wherein the tapered area is angled at an angle A5 of between approximately 43.5°

and 44.5°

relative to a vertical plane extending through the optics cup.

11. The optics cup according to claim 1, wherein each of the side walls has an angle B1, B2 of approximately 3°

in a direction outwardly as the side walls extend upwardly from the floor with respect to a vertical axis extending through the rectangular opening.

12. The disposable sample cup according to claim 1, wherein said second end wall extends at an angle B3 of between 1°

-3°

with respect to a vertical axis extending through a meeting point between the floor and said second end wall.

13. The disposable sample cup according to claim 10, wherein angle A5 is 44.5°

and angle B3 is 1°

.

14. The disposable sample cup according to claim 10, wherein angle A5 is 43.5°

and angle B3 is 3°

.

15. The disposable sample cup according to claim 1, wherein the tapered area of the first end wall is oriented with respect to the second end wall such that an illuminating beam travelling along a vertical axis and directed downwardly at the tapered area will reflect from the tapered area to the second end wall, back to the tapered area and back along a line parallel to the vertical axis.

16. The optics cup as claimed in claim 1, wherein the container is made of a transparent material.

17. The optics cup according to claim 1, wherein each of the side walls extends downwardly from the rectangular opening to the floor at a constant angle.

18. The optics cup of claim 2 wherein the reflective layer is on an inner surface of the container.

19. The optics cup according to claim 1, wherein the tapered area is planar.

20. An optics cup for holding a biological sample for use in an optical analysis comprising:

a generally rectangular-shaped container adapted to contain the biological sample, said container including a top rectangular opening, a pair of side walls having a longitudinal axis therebetween, a first end wall, and a second end wall spaced apart from the first end wall, and a floor, and wherein the second end wall extends at an angle B3 of between 1°

-3°

with respect to a vertical axis extending through a meeting point between the floor and the second end wall,

said container having a rectangular opening for receiving the biological sample and a lower tapered area extending from the first end wall in an inwardly and downwardly direction relative to the rectangular opening,

wherein the tapered area extends downwardly to the floor and wherein the tapered area is angled at an angle of between approximately 43.5° and

44.5°

relative to a vertical plane extending through the optics cup,

wherein the floor has the shape of an inverted arch extending along the entire length of the floor,

wherein the inverted arch is symmetric about and uniform along the longitudinal axis and the arch is curved,

wherein a portion of the container along at least the tapered area has a layer of reflective material for reflecting illumination introduced into the top opening and to enhance light collection through the biological sample for the optical analysis of the biological sample, and

wherein the arch is oriented such that the light inside the illuminated cup traveling away from an optical collection cone will be reflected to collection points along the longitudinal axis.

21. The optics cup as claimed in claim 20, wherein the container is made of a transparent material.

22. The optics cup according to claim 20, wherein the tapered area is planar.

23. An optics cup for holding a biological sample for use in an optical analysis comprising:

a generally rectangular-shaped container with a top rectangular opening and adapted to contain the biological sample, said container including a pair of side walls having a longitudinal axis therebetween, a first end wall, and a second end wall spaced apart from the first end wall, and a floor,

said container having a rectangular opening for receiving the biological sample and a lower tapered area extending from the first end wall in an inwardly and downwardly direction relative to the rectangular opening,

wherein the tapered area extends downwardly to the floor,

wherein the floor has the shape of an inverted arch extending along the entire length of the floor,

wherein the inverted arch is symmetric about and uniform along the longitudinal axis and the arch is curved,

wherein a portion of the container along at least the tapered area is reflective for reflecting illumination introduced into the top opening and for light collection to enhance optical analysis of the biological sample

wherein the arch is oriented such that the light inside the illuminated cup traveling away from an optical collection cone will be reflected to collection points along the longitudinal axis.

24. The optics cup according to claim 23, wherein the arch has a single radius of curvature along the length.

25. The optics cup according to claim 23, wherein the arch is elliptical along the length.

26. The optics cup according to claim 23, wherein the tapered area is planar.