Method of evaporation control of a sample stored in a cold container

• US 9,863,969 B2
• Filed: 06/19/2015
• Issued: 01/09/2018
• Est. Priority Date: 05/16/2007
• Status: Active Grant

• Current Assignee: Hitachi High-Tech Company Limited (Hitachi, Ltd.)
• Original Assignee: Hitachi High-Technologies Corporation (Hitachi, Ltd.)
• Inventors: Onizawa, Kuniaki, Obari, Koichi, Oizumi, Junichi, Oba, Shigemi, Abe, Tetsuaki
• Primary Examiner(s): Conley, Sean E
• Assistant Examiner(s): Whatley, Benjamin R
• Application Number:
  US14/744,117
• Publication Number:
  US 20150285828A1
• Time in Patent Office: 935 Days
• Field of Search: None
• CPC Class Codes: G01N 2001/1081 Storing samples under refrigeration
• CPC Class Codes: G01N 2035/00346 Heating or cooling arrangements
• CPC Class Codes: G01N 2035/00445 Other cooling arrangements
• CPC Class Codes: G01N 2035/0462 Buffers [FIFO] or stacks [LIFO] for holding carriers between operations
• CPC Class Codes: G01N 35/026 having blocks or racks of reaction cells or cuvettes
• CPC Class Codes: G05B 1/00 Comparing elements, i.e. elements for effecting comparison directly or indirectly between a desired value and existing or anticipated values

Abstract

A method of evaporation control of a sample which is stored in a thermally insulated state is configured for preventing evaporation or denaturing of the samples and specimens. The method includes carrying the samples contained in individual containers out from a cold container having a capability of cold storage. An elapsed time that each sample container has been removed from the cold container is measured and is compared with a preset time. If the elapsed time is less than the preset time, the sample container can be returned to the cold container. An alarm is output if the elapsed time exceeds the preset time.

Claims

1. A method of evaporation control of a sample stored in a cold container, the method comprising the steps of:

providing a cooler for the cold container and using the cooler for controlling a temperature in the cold container using a temperature control;

storing a plurality of separate individual sample container racks in the cold container;

providing a sample handling unit including a rack transfer mechanism having a rack holding bucket and a carriage to transfer the rack to or from the rack holding bucket;

using the rack transfer mechanism for accessing selected ones of the sample container racks in the cold container;

carrying a selected one of the sample container racks out of the cold container using the sample handling unit using the rack transfer mechanism;

measuring, by an operating system including a computer, an elapsed time starting from a time when the sample in the selected sample container rack is carried out from the cold container by the sample handling unit;

storing a first preset time in the operating system of the computer, wherein the operating system is configured to compare the measured elapsed time starting from the time the sample in the selected sample container rack is carried out from the cold container with the first preset time stored in the operating system; and

returning the selected sample container rack into the cold container, using the sample handling unit, in response to determining, using the operating system, that the measured elapsed time starting from the time that sample container rack is carried out from the cold container, is less than the first preset time stored in the operating system.

2. The method according to claim 1, further comprising outputting an alarm by the operating system in response to the operating system determining that the measured elapsed time starting from the time the sample in the selected sample container rack is carried out from the cold container, is not less than the first preset time.

3. The method according to claim 1, further comprising determining if the selected sample container rack can be carried out from the cold container, using the sample handling unit, before carrying the selected sample container out of the cold container, by comparing a cold storage time that the selected sample container has been stored in the cold storage container with a second preset time using the operating system.

4. The method according to claim 3, wherein the first preset time and the second preset time are set in the operating system by a user.