Systems and methods for fluid delivery

• US 9,867,930 B2
• Filed: 07/21/2014
• Issued: 01/16/2018
• Est. Priority Date: 09/15/2008
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Kamen, Dean, Kerwin, John M., Gray, Larry B., Mandro, Marc A., Blumberg, Jr., David
• Primary Examiner(s): LANDRY II, GERALD ERNEST
• Application Number:
  US14/336,530
• Publication Number:
  US 20150045767A1
• Time in Patent Office: 1,275 Days
• Field of Search: 604 611, 604 65- 67, 604131-155, 6048901
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2005/16863 Occlusion detection
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 2205/0294 Piezoelectric materials
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3546 Range
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/8237 Charging means
• CPC Class Codes: A61M 2206/22 eliminating pulsatile flows, e.g. by the provision of a dampening chamber
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 : of the skin patch type
• CPC Class Codes: A61M 5/14586 : pressurised by means of a flexible diaphragm
• CPC Class Codes: A61M 5/16809 : by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: A61M 5/16886 : for measuring fluid flow rate, i.e. flowmeters
• CPC Class Codes: A61M 5/172 : electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G01F 11/086 : using an auxiliary pressure to cooperate with the diaphragm or bellows
• CPC Class Codes: G05D 7/0647 : the plurality of throttling means being arranged in series
• CPC Class Codes: G05D 7/0676 : by action on flow sources G05D7/0688, G05D7/0694 take precedence
• CPC Class Codes: G08C 17/02 : using a radio link
• CPC Class Codes: H04B 7/2609 : Arrangements for range control, e.g. by using remote antennas
• CPC Class Codes: Y10T 29/49236 : Fluid pump or compressor making
• CPC Class Codes: Y10T 29/494 : Fluidic or fluid actuated device making
• CPC Class Codes: Y10T 29/49412 : with assembly, disassembly or composite article making
• CPC Class Codes: Y10T 29/49826 : Assembling or joining
• CPC Class Codes: Y10T 29/49828 : Progressively advancing of work assembly station or assembled portion of work

Abstract

A system for at least partial closed-loop control of a medical condition is disclosed. The system includes at least one medical fluid pump. The medical fluid pump including a sensor for determining the volume of fluid pumped by the pump. Also, at least one continuous analyte monitor, and a controller. The controller is in communication with the medical fluid pump and the at least one continuous analyte monitor. The controller includes a processor. The processor includes instructions for delivery of medical fluid based at least on data received from the at least one continuous analyte monitor.

Claims

1. A system for at least partial closed-loop control of a medical condition, the system comprising:

a medical fluid infusion pump comprising an acoustic volume sensor for measuring the volume of medical fluid pumped to a patient by the medical fluid infusion pump;

at least a first continuous glucose sensor and a second continuous glucose sensor; and

a controller in communication with at least two continuous glucose monitors, the controller comprising a processor,

wherein the first continuous glucose sensor and the second continuous glucose sensor send electrical signals to the processor in the controller and the processor in the controller correlates the electrical signals to a glucose value, and

wherein if a glucose value from the first continuous glucose sensor differs by greater than a predetermined threshold amount from a glucose value from the second continuous glucose sensor, then the glucose value from the first continuous glucose sensor and the glucose value from the second continuous glucose sensor are disregarded.

2. The system of claim 1, wherein the first continuous glucose sensor is calibrated differently from the second continuous glucose sensor.

3. The system of claim 1, wherein if the processor does not receive an electrical signal from either the first continuous glucose sensor or the second continuous glucose sensor, the processor disregards future electrical signals from that continuous glucose sensor.

4. The system of claim 1, wherein the first continuous glucose sensor and the second continuous glucose sensor are tuned to different dynamic ranges.

5. The system of claim 1, wherein the first continuous glucose sensor is tuned wherein it is sensitive to low blood glucose levels.

6. The system of claim 5, wherein the second continuous glucose sensor is tuned wherein it is sensitive to high blood glucose levels.

7. The system of claim 1, wherein the first continuous glucose sensor and the second continuous glucose sensor are tuned based on a time constant.

8. The system of claim 1, wherein the first continuous glucose sensor and the second continuous glucose sensor are introduced to different depths in a patient.

9. The system of claim 1, further comprising an inertial measurement unit.

10. The system of claim 1, further comprising a heart rate sensor.

11. A method for at least partial closed-loop control of a medical condition, the method comprising:

providing a medical fluid infusion pump comprising an acoustic volume sensor for measuring the volume of medical fluid pumped to a patient by the medical fluid infusion pump;

providing at least a first continuous glucose sensor and a second continuous glucose sensor;

providing a controller in communication with at least two continuous glucose monitors, the controller comprising a processor;

the first continuous glucose sensor and the second continuous glucose sensor sending electrical signals to the processor in the controller and the processor in the controller correlating the electrical signals to a glucose value, and

if a glucose value from the first continuous glucose sensor differs by greater than a predetermined threshold amount from a glucose value from the second continuous glucose sensor, then disregarding the glucose value from the first continuous glucose sensor and the glucose value from the second continuous glucose sensor.

12. The method of claim 11, further comprising calibrating the first continuous glucose sensor differently from the second continuous glucose sensor.

13. The method of claim 11, further comprising if the processor does not receive an electrical signal from either the first continuous glucose sensor or the second continuous glucose sensor, the disregarding future electrical signals from that continuous glucose sensor.

14. The method of claim 11, further comprising tuning the first continuous glucose sensor and the second continuous glucose sensor to different dynamic ranges.

15. The method of claim 11, further comprising tuning the first continuous glucose sensor to be sensitive to low blood glucose levels.

16. The method of claim 15, further comprising tuning the second continuous glucose sensor to be sensitive to high blood glucose levels.

17. The method of claim 11, further comprising tuning the first continuous glucose sensor and the second continuous glucose sensor based on a time constant.

18. The method of claim 11, further comprising introducing the first continuous glucose sensor and the second continuous glucose sensor are to different depths in a patient.

19. The method of claim 11, further comprising providing an inertial measurement unit.

20. The method of claim 11, further comprising providing a heart rate sensor.