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Drug infusion system and method for controlling blood pressure

  • US 9,867,936 B2
  • Filed: 09/15/2011
  • Issued: 01/16/2018
  • Est. Priority Date: 09/15/2010
  • Status: Active Grant
First Claim
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1. A method of controlling a blood pressure of a subject, comprising:

  • (a) calibrating a blood pressure baseline for the subject;

    (b) selecting a blood pressure threshold corresponding to said blood pressure baseline;

    (c) calibrating a heart rate baseline for the subject;

    (d) selecting a heart rate threshold corresponding to said heart rate baseline;

    (e) calculating a final mean blood pressure indicating the blood pressure of the subject during a pre-determined period, wherein the blood pressure is generated by a non-invasive blood pressure data generating unit such that calculating the final mean blood pressure includes the step of applying a greater weight to blood pressure measured in a later part of the pre-determined period than during an earlier part, wherein the earlier part of the pre-determined period is longer than the later part of the pre-determined period and wherein the step of applying a greater weight to blood pressure measured in the later part of the pre-determined period comprises the steps of;

    (i) calculating an earlier part mean blood pressure from blood pressure readings for each second up to the end of the earlier part of the pre-determined period to obtain the earlier part mean blood pressure;

    (ii) calculating a later part mean blood pressure from blood pressure readings for each second during the later part of the pre-determined period to obtain the later part mean blood pressure; and

    then(iii) calculating the final mean blood pressure as an average of the earlier part mean blood pressure and the later part mean blood pressure;

    (f) generating heart rate data indicating a heart rate of the subject;

    (g) controlling a plurality of pumps to infuse drugs into the subject, wherein each of the plurality of pumps is adapted to infuse one out of a plurality of different drugs into the subject, and wherein each of the plurality of different drugs has a particular influence on the blood pressure of the subject;

    wherein the plurality of pumps is controlled such that, in dependence on the final mean blood pressure relative to the blood pressure threshold and the heart rate data relative to the heart rate threshold, a mix of drugs is infused into the subject which stabilizes the blood pressure of the subject, wherein the plurality of pumps is controlled to infuse drugs into the subject if the blood pressure of the subject falls below the blood pressure threshold, wherein the injection of drugs into the subject is continued in regular time intervals ranging between 15 and 30 seconds until the blood pressure exceeds the blood pressure threshold.

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