Adipose tissue combinations, devices, and uses thereof

• US 9,867,939 B2
• Filed: 03/11/2014
• Issued: 01/16/2018
• Est. Priority Date: 03/12/2013
• Status: Active Grant

• Current Assignee: Allergan Incorporated (Abbvie Incorporated)
• Original Assignee: Allergan Incorporated (Abbvie Incorporated)
• Inventors: Schwab, Justin, Augarten, Mike, Messina, Darin, Metzner, Jason, Franklin, Ethan
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Swanson, Leah
• Application Number:
  US14/204,796
• Publication Number:
  US 20140276384A1
• Time in Patent Office: 1,407 Days
• CPC Class Codes: A61K 35/35 Fat tissue; Adipocytes; Stromal cells; Connective tissues adipose-derived stem cells A61K35/28; collagen A61K38/39
• CPC Class Codes: A61M 1/63 with means for emptying the suction container, e.g. by interrupting suction
• CPC Class Codes: A61M 1/69 Drainage containers not being adapted for subjection to vacuum, e.g. bags devices worn by the patient for reception of urine A61F5/44
• CPC Class Codes: A61M 1/895 with means for reinjection of collected fat
• CPC Class Codes: A61M 2005/3142 Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
• CPC Class Codes: A61M 2202/08 Lipoids
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2209/086 Docking stations
• CPC Class Codes: A61M 3/005 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3145 Filters incorporated in syringes
• CPC Class Codes: C12N 5/0653 Adipocytes; Adipose tissue

Abstract

Described are devices, systems, and methods for processing adipose tissue for reintroduction into a body. In some embodiments, adipose tissue is mixed with an additive prior to reintroduction.

Claims

1. A system for processing adipose tissue for reintroduction into the body, the system comprising:

a container including a first compartment, a second compartment, a third compartment, and a tortuous path having a plurality of sharp turns and extending between the second and third compartments, each of the first, second, and third compartments being positioned at different vertical levels of the container to induce movement of harvested adipose tissue by gravity;

wherein the first compartment is configured to receive and filter the harvested adipose tissue, wherein the second compartment is connected to the first compartment and includes an additive injector, the tortuous path configured to mix and convey additive and fat from the second compartment to the third compartment, and wherein the third compartment is connected to the second compartment via the tortuous path and is configured to dispense adipose tissue and additive to a patient.

2. The system of claim 1, further comprising an additional compartment including the tortuous path connecting the second compartment with the third compartment.

3. The system of claim 1, further comprising a frangible seal separates the first compartment from the second compartment, the seal being breakable by an operator to permit flow from the first compartment to the second compartment.

4. The system of claim 1, further comprising a filter fluidly interconnecting the first compartment with the second compartment to permit flow of harvested adipose tissue therethrough.

5. The system of claim 1, wherein the additive is a hydrogel.

6. The system of claim 1, wherein the additive includes hyaluronic acid.

7. The system of claim 1, wherein the tortuous path extends along a plurality of vertical and horizontal planes interposed between the second and third compartments.

8. The system of claim 1, wherein the second compartment comprises a port for removing processed adipose tissue therefrom.

9. The system of claim 1, wherein the additive injector comprises a port for injecting the additive into the second compartment.

10. The system of claim 1, wherein the additive injector comprises a pouch for dispensing the additive into the second compartment.

11. The system of claim 1, wherein the tortuous path does not vertically overlap with the second or third compartments.