Method of measuring hematocrit (HCT), and measurement device using the method

• US 9,869,654 B2
• Filed: 11/29/2013
• Issued: 01/16/2018
• Est. Priority Date: 11/29/2013
• Status: Active Grant

• Current Assignee: Broadmaster Biotech Corp.
• Original Assignee: Broadmaster Biotech Corp.
• Inventors: Chen, Yi-Lung, Lai, Chien-Hung, Lin, Po-Hao, Lin, Ya-Sian, Chen, Yi-Chen, Jiang, Fang-Yi, Yang, Shu-Wei, Tai, Yu-Hsuan, Lu, Shih-Jen
• Primary Examiner(s): Kaur, Gurpreet
• Application Number:
  US14/093,262
• Publication Number:
  US 20150153298A1
• Time in Patent Office: 1,509 Days
• CPC Class Codes: A61B 5/14535 for measuring haematocrit
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: G01N 33/49 Blood chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80

Abstract

A method of measuring hematocrit (HCT) and a measurement device using in the method and depends on an electrode test specimen to create a capacitor charging effect and consequential change in discharge current for measurement of hematocrit. The method of measuring hematocrit comprises steps as follows: (a) Instill blood into a pair of test electrodes which is installed in the present invention and apply a voltage to the pair of test electrodes; (b) Remove the voltage applied to the pair of test electrodes and measure a discharge current value; (c) Refer to a predetermined decision rule and the discharge current to obtain a hematocrit value for blood. As such, the present invention which relies on an electrode test specimen in measurement of hematocrit corresponding to a discharge current value during electric discharge contributes to precision and reliability in contrast to conventional hematocrit tests.

Claims

1. A method of measuring hematocrit, comprising:

Step 1;

Instill blood into a pair of test electrodes and apply a voltage to said pair of test electrodes;

Step 2;

Remove said voltage applied to said pair of test electrodes and measure a discharge current value; and

Step 3;

Refer to a predetermined decision rule and said discharge current value to obtain a hematocrit value for blood,

wherein said measuring a discharge current value in Step 2 is to measure a discharge current value in less than 0.005 second after said voltage is removed.

2. The method of measuring hematocrit according to claim 1 characterized in that said applied voltage to said pair of test electrodes in Step 1, said applied voltage is between 1 and 3 volts.

3. The method of measuring hematocrit according to claim 1 characterized in that said applied voltage to said pair of test electrodes in Step 1, a duration of said applied voltage is within 0.01 through 1 second.

4. The method of measuring hematocrit according to claim 1 characterized in that said pair of test electrodes in Step 1 is separated by a distance of 0.6 mm to 0.05 mm.

5. The method of measuring hematocrit according to claim 1 characterized in that said predetermined decision rule in Step 3 comprises multiple hematocrit data which presents relationships between hematocrit and discharge current values under different voltage values for determining a hematocrit value of said blood.