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Analyzing bacteria without culturing

  • US 9,869,671 B2
  • Filed: 04/25/2017
  • Issued: 01/16/2018
  • Est. Priority Date: 04/21/2010
  • Status: Active Grant
First Claim
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1. A method for analyzing a bacterium from a sample, the method comprising:

  • providing a vessel that contains a body fluid sample comprising a bacterium;

    introducing to the sample in the vessel, magnetic particles comprising a bacterium-specific binding moiety and a buffer that promotes binding of the particles to the bacterium in order to create a mixture containing bacterium/magnetic particle complexes;

    flowing the mixture from the vessel into a fluidic device through a channel in the fluidic device and toward a magnet;

    applying a magnetic field to isolate the bacterium/magnetic particle complexes from the sample; and

    analyzing the bacterium.

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