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Morphology identification in tissue samples based on comparison to named feature vectors

  • US 9,870,615 B2
  • Filed: 07/19/2017
  • Issued: 01/16/2018
  • Est. Priority Date: 07/19/2017
  • Status: Active Grant
First Claim
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1. A method of locating morphology in a tissue sample, comprises the steps of:

  • obtaining a first, second, and third tissue sample, each removed from an organism;

    taking a microscope to each said first, second, and third tissue sample and digitizing magnified image of said first tissue sample, said second, and said third tissue sample;

    receiving a selection of at least one superpixel of said image of said first tissue sample;

    receiving a named morphology for said at least one superpixel and converting said at least one superpixel into a first feature vector;

    extracting superpixels of said image of said second tissue sample and converting each superpixel of said second image of said second tissue into second feature vectors;

    finding, using a processor carrying out instructions, within said second feature vectors of said second tissue, a nearest match feature vector to said first feature vector; and

    indicating that a superpixel of said second image associated with said nearest match feature vector is possibly a representation of said named morphology;

    after receiving confirmation of a name of said named morphology from a viewer for said named morphology a threshold number of minimum times, a name of said named morphology becomes unchangeable for future scanned superpixels determined to be associated with said named morphology; and

    wherein said third tissue sample has a third superpixel with a feature vector indicated as being a nearest match to a feature vector found in one of said first or said second tissue samples;

    further wherein said third superpixel and corresponding superpixels associated with said match feature vector of said first or said second tissue sample are unnamed;

    exhibiting at least one of said third superpixel and said corresponding superpixels;

    requesting a name for said at least one of said third superpixel and said corresponding superpixels; and

    providing said name at a future time when a feature vector is found corresponding to said third superpixel.

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