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Probe for extraction of molecules of interest from a sample

  • US 9,870,907 B2
  • Filed: 06/12/2015
  • Issued: 01/16/2018
  • Est. Priority Date: 03/11/2002
  • Status: Expired due to Term
First Claim
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1. A device for generating ionized molecules for analysis in a mass spectrometer, the device comprising:

  • a mesh substrate coated with an extraction phase of substantially uniform thickness that is from about 0.2 μ

    m to about 50 μ

    m, the extraction phase comprising;

    a polymer that absorbs a molecule of interest from a matrix, ora polymer and solid phase microextraction (SPME) particles having pores dimensioned to adsorb a molecule of interest from a matrix,wherein the coated mesh substrate has a sufficiently open structure to allow fluid to flow through the coated mesh substrate; and

    a solid substrate connected to the mesh substrate to provide stability to the coated mesh substrate.

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