Multi-pole synchronous pulmonary artery radiofrequency ablation catheter

• US 9,872,720 B2
• Filed: 03/27/2015
• Issued: 01/23/2018
• Est. Priority Date: 11/13/2012
• Status: Active Grant

• Current Assignee: PULNOVO MEDICAL (WUXI) CO., LTD.
• Original Assignee: PULNOVO MEDICAL (WUXI) CO., LTD.
• Inventors: Chen, Shaoliang
• Primary Examiner(s): Della, Jaymi
• Application Number:
  US14/672,021
• Publication Number:
  US 20150201988A1
• Time in Patent Office: 1,033 Days
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/320069 for ablating tissue
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00345 Vascular system
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00613 Irreversible electroporation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00916 with means for switching or controlling the main function of the instrument or device
• CPC Class Codes: A61B 2018/00988 Means for storing information, e.g. calibration constants, or for preventing excessive use, e.g. usage, service life counter
• CPC Class Codes: A61B 2018/124 switching the output to different electrodes, e.g. sequentially
• CPC Class Codes: A61B 2018/1407 Loop
• CPC Class Codes: A61B 2018/144 : Wire
• CPC Class Codes: A61B 2018/1467 : using more than two electrodes on a single probe
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61N 1/06 : for high-frequency therapy

Abstract

Disclosed herein is a controller for controlling ablation of a target tissue of a patient with an ablation device comprising at least one electrode and at least one sensor. The controller typically comprises a storage medium and one or more computing devices operably coupled with the storage medium. The storage medium can comprise patient image data and the one or more computing devices are configured to direct power to the at least one electrode.

Claims

1. A controller for controlling ablation of a target tissue of a patient with an ablation device comprising at least one electrode and at least one sensor, the controller comprising:

a storage medium having stored thereon patient image data including a distal end of a main pulmonary artery, a proximal end of a left pulmonary artery, and a proximal end of a right pulmonary artery; and

one or more computing devices operably coupled with the storage medium and the ablation device, the one or more computing devices configured to execute instructions comprising;

(i) directing power to the at least one electrode positioned against a target tissue at a power level sufficient for ablating the target tissue, said target tissue being identified based on the patient image data and further comprising a left lateral side of the distal end of the main pulmonary artery,

(ii) determining, based on sensor data received from the at least one sensor, an amount of time the ablation is to be performed at a location of the target tissue, wherein the sensor data comprises one or more characteristics of the target tissue, and

(iii) regulating the directed power to the at least one electrode or the amount of time the ablation is performed at the location of the target tissue such that the target tissue is ablated to affect a reduction in mean pulmonary artery pressure of the patient.

2. The controller of claim 1, wherein the one or more computing devices are configured to execute the instructions comprising directing the power to the at least one electrode positioned against the target tissue comprising a left lateral apex of the distal end of the main pulmonary artery.

3. The controller of claim 1, wherein the at least one electrode comprises a first electrode and a second electrode, and wherein the one or more computing devices are configured to execute the instructions comprising directing the power to the first electrode positioned against a first portion of the target tissue comprising a left lateral apex of the distal end of the main pulmonary artery, and directing the power to the second electrode positioned against a second portion of the target tissue comprising an anterior side or a posterior side of the left lateral apex of the distal end of the main pulmonary artery.

4. The controller of claim 3, wherein the at least one sensor comprises a first sensor and a second sensor, the first sensor connected with the first electrode and the second sensor connected with the second electrode, and wherein the one or more computing devices are configured to execute the instructions comprising (iv) determining, based on the sensor data received from the first sensor, the amount of time ablation is to be performed at the location of the first portion of the target tissue, and (v) determining, based on the sensor data received from the second sensor, the amount of time ablation is to be performed at the location of the second portion of the target tissue.

5. The controller of claim 4, further comprising a display operably coupled with the one or more computing devices, wherein the one or more computing devices are further configured to execute the instructions which further comprise displaying on the display the sensor data received from the first sensor while directing the power to the first electrode, and the sensor data received from the second sensor while directing the power to the second electrode.

6. The controller of claim 5, wherein the sensor data received from the second sensor is configured to be displayed on the display after the one or more computing devices stop directing the power to the first electrode.

7. The controller of claim 1, further comprising a battery operably coupled with the one or more computing devices and configured to store the power at the power level sufficient for ablating the target tissue, wherein the one or more computing devices are configured to execute the instructions comprising directing the power to the at least one electrode from the battery.

8. The controller of claim 7, wherein the at least one electrode comprises a first electrode and a second electrode, and, wherein the one or more computing devices are configured to execute the instructions comprising:

directing the power from the battery to the first electrode positioned against a first portion of the target tissue comprising a left lateral apex of the distal end of the main pulmonary artery, and

directing the power from the battery to the second electrode positioned against a second portion of the target tissue comprising an anterior side or a posterior side of the left lateral apex of the distal end of the main pulmonary artery.

9. The controller of claim 7, wherein the battery is configured to be charged, and wherein the one or more, computing devices are configured to execute instructions comprising directing the power from the battery to the second electrode after the battery has finished charging.

10. The controller of claim 7, wherein the battery is configured to be charged, and wherein the one or more computing devices are configured to execute the instructions comprising directing the power from the battery to the at least one electrode after the battery has finished charging.

11. The controller of claim 1, further comprising a display operably coupled with the one or more computing devices, wherein the one or more computing devices are further configured to execute the instructions which further comprise displaying on the display the sensor data received from the at least one first sensor while directing the power to the at least one electrode.

12. A computer-implemented method for controlling ablation of a target tissue of a patient with an ablation device comprising at least one electrode and at least one sensor, the method comprising:

under control of one or more computing devices executing specific computer executable instructions,

(i) directing power to the at least one electrode positioned against a target tissue at a power level sufficient for ablating the target tissue, said target tissue being identified based on patient image data stored on a storage medium of the one or more computing devices, the patient image data including a distal end of a main pulmonary artery, a proximal end of a left pulmonary artery, and a proximal end of a right pulmonary artery, wherein said target tissue comprises a left lateral side of the distal end of the main pulmonary artery;

(ii) determining, based on sensor data received from the at least one sensor, an amount of time the ablation is to be performed at a location of the target tissue, wherein the sensor data comprises one or more characteristics of the target tissue, and

(iii) regulating the directed power to the at least one electrode or the amount of time the ablation is performed at the location of the target tissue, such that the target tissue is ablated to affect a reduction in mean pulmonary artery pressure of the patient.

13. The computer-implemented method of claim 12, wherein the at least one electrode comprises a first electrode and a second electrode, and further comprising switching from directing power to the first electrode of the ablation device, the first electrode positioned against a first portion of the target tissue, to directing power to the second electrode of the ablation device, the second electrode positioned against a second portion of the target tissue, wherein the switching is performed using a mechanical switch that comprises at least one moving part.

14. The computer-implemented method of claim 13, wherein the switching is performed using a rotatable knob.

15. The computer-implemented method of claim 12, wherein the at least one electrode comprises a first electrode and a second electrode, and further comprising switching from directing the power to the first electrode of the ablation device, the first electrode positioned against a first portion of the target tissue, to directing power to the second electrode of the ablation device, the second electrode positioned against a second portion of the target tissue, wherein the switching is performed using a switching system comprising:

a mechanical switch that comprises at least one moving part, and

a solid state switch that comprises no moving parts.

16. The computer-implemented method of claim 12, comprising directing the power to the at least electrode positioned against the target tissue comprising a left lateral apex of the distal end of the pulmonary artery.

17. The computer-implemented method of claim 12, wherein the at least one electrode comprises a first electrode and a second electrode, and wherein the method comprises directing the power to the first electrode positioned against a first portion of the target tissue comprising a left lateral apex of the distal end of the main pulmonary artery, and directing the power to the second electrode positioned against a second portion of the target tissue comprising an anterior side or a posterior side of the left lateral apex of the distal end of the main pulmonary artery.

18. A computer-readable, non-transitory storage medium storing computer executable instructions that, when executed by one or more computer systems, configure the one or more computer systems to perform operations comprising:

(i) directing power to at least one electrode of an ablation device operably coupled with the one or more computer systems, wherein the at least one electrode is positioned against a target tissue of a patient, and wherein the power is directed to the at least one electrode at a first power level sufficient for ablating the target tissue, said target tissue being identified based on patient image data stored on a storage medium of the one or more computer systems, the patient image data including a distal end of a main pulmonary artery, a proximal end of a left pulmonary artery, and a proximal end of a right pulmonary artery, wherein said target tissue comprises a left lateral side of the distal end of the main pulmonary artery;

(ii) determining, based on sensor data received from at least one sensor of the ablation device, an amount of time the ablation is to be performed at a location of the target tissue, wherein the sensor data comprises one or more characteristics of the target tissue, and

(iii) regulating the directed power to the at least one electrode or the amount of time the ablation is performed at the location of the target tissue, such that the target tissue is ablated to affect a reduction in mean pulmonary artery pressure of the patient.

19. The computer-readable, non-transitory storage medium of claim 18, wherein the at least one electrode comprises a first electrode and a second electrode, wherein the computer executable instructions further configure the one or more computer systems to perform operations comprising switching from directing power to the first electrode of the ablation device to directing power to the second electrode of the ablation device, wherein the switching is performed by controlling a solid state switch that comprises no moving parts.

20. The computer-readable, non-transitory storage medium of claim 18, wherein the power is directed to the at least one electrode positioned against the target tissue comprising a left lateral apex of the distal end of the pulmonary artery.

21. The computer-readable, non-transitory storage medium of claim 18, wherein the at least one electrode comprises a first electrode and a second electrode, and wherein the power is directed to the first electrode positioned against a first portion of the target tissue comprising a left lateral apex of the distal end of the main pulmonary artery, and wherein the power is directed to the second electrode positioned against a second portion of the target tissue comprising an anterior side or a posterior side of the left lateral apex of the distal end of the main pulmonary artery.