Apparatus, systems, and methods for detecting congenital heart disease in newborns

• US 9,877,671 B2
• Filed: 10/16/2014
• Issued: 01/30/2018
• Est. Priority Date: 10/21/2013
• Status: Active Grant

• Current Assignee: Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center (University of California)
• Original Assignee: Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center (University of California)
• Inventors: Chang, Ruey-Kang
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US14/515,820
• Publication Number:
  US 20150112171A1
• Time in Patent Office: 1,202 Days
• CPC Class Codes: A61B 2503/045 Newborns, e.g. premature baby monitoring
• CPC Class Codes: A61B 5/0015 characterised by features of the telemetry system
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/4538 Evaluating a particular part of the muscoloskeletal system or a particular medical condition
• CPC Class Codes: A61B 5/6825 Hand
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure

Abstract

Apparatus configured to detect congenital heart disease (CHD) in newborns may comprise a body with a cavity configured to receive a hand or foot of a newborn. Sensor pairs of the apparatus may be configured scan such that the best signals can be selected, which can accommodate for movements of the newborn and/or facilitate impartialness as to which body part is inserted in the apparatus. Positions of the sensor pairs may be adjusted to ensure contact with the newborn'"'"'s skin. A disposable cover may protect the newborn'"'"'s skin from contacting the apparatus. The apparatus may include a pressure device so that CHD threshold values can be adjusted for different altitudes. The apparatus may integrate with electronic medical record (EMR) systems.

Claims

1. Apparatus configured to detect CHD in newborns, the apparatus comprising:

a body comprising a cavity configured to receive a portion of a hand or a foot of a newborn, the cavity substantially encompassing the portion of the newborn'"'"'s hand or foot when the portion of the newborn'"'"'s hand or foot is received by the cavity;

sensor pairs including a first sensor pair, individual ones of the two or more sensor pairs being configured to provide detection signals conveying information associated with oxygen saturation, the first sensor pair including a first light emitter and a corresponding first light detector disposed at opposing locations in the cavity of the body such that, when the portion of the newborn'"'"'s hand or foot is inside the cavity, light from the first light emitter that passes through the newborn'"'"'s hand or foot is detected by the first light detector;

one or more hardware processors configured by machine-readable instructions to;

select a subset of the detection signals provided by the sensor pairs based on a determination of which body part of the newborn is received by the cavity, the body part being a portion of one of a left foot, a right foot, a left hand, or a right hand;

determine a saturation value indicative of oxygen saturation of the newborn based on the selected subset of the detection signals, wherein the saturation value is determined based on one or more detection signals provided by the sensor pairs;

determine a presence of CHD in the newborn responsive to the saturation value breaching a threshold saturation value, wherein the presence of CHD is determined responsive to the saturation value breaching a threshold saturation value; and

determine an ambient air pressure in the environment surrounding the apparatus based on a pressure signal provided by a pressure device; and

a sensor positioning device configured to reposition individual ones of the two or more sensor pairs responsive to the portion of the newborn'"'"'s hand or foot being received by the cavity, wherein repositioning the first sensor pair includes a combination of transitional and rotational movement configured to move one or both of the first light emitter or the first light detector such that one or both of the first light emitter or the first light detector configured to contact skin of the portion of the newborn'"'"'s hand or foot, wherein the sensor positioning device includes one or more of a spring, a cushion, an elastic mechanism, an inelastic mechanism, a motorized arm, or a motor configured to adjust, by repositioning, automatically, manually, or in some combination thereof, one or both of the first light emitter or the first light detector of a sensor pair, wherein the adjustment is accomplished in relation to an attachment point of the sensor positioning device, wherein the sensor positioning device is configured to adjust a sensor using the combination of translational and rotational movement, wherein translational movement includes one or more of movement perpendicular to or movement lateral to the attachment point of the sensor positioning device, wherein perpendicular movement includes compression toward and extension from a wall, wherein lateral movement includes planar movement perpendicular to the plane in which compression or extension occurs, wherein rotational movement includes changing the angle of a sensor in relation to the wall, and wherein the sensor pair is configured to be repositioned responsive to the portion of the newborn'"'"'s hand or foot being received by the cavity of body, wherein repositioning the sensor pair includes moving one or both of the light emitter or the light detector of the sensor pair such that one or both of the light emitter or the light detector configured to contact skin on the portion of the newborn'"'"'s hand or foot that is within the cavity wherein one or both of the first light emitter or the first light detector of the given sensor pair may be moved along an axis that passes through both the light emitter and the light detector, and wherein lateral alignment between the light emitter and the light detector of the sensor pair is maintained after being adjusted.

2. The apparatus of claim 1, wherein the sensor pairs are configured to perform scans simultaneously.

3. The apparatus of claim 1, wherein the sensor pairs are configured to perform scans cyclically one sensor pair at a time.

4. The apparatus of claim 1, wherein the one or more hardware processors are further configured by machine-readable instructions such that the threshold saturation value is adjusted based on the ambient air pressure to reduce a probability of false positives attributable to high-altitude environments.

5. The apparatus of claim 1, wherein the one or more hardware processors are further configured by machine-readable instructions such that the threshold saturation value is adjusted downward for ambient air pressures that are lower than atmospheric pressure at sea level.

6. The apparatus of claim 1, wherein the one or more hardware processors are further configured by machine-readable instructions to access an EMR associated with the newborn.

7. The apparatus of claim 1, further including a disposable cover configured to line the cavity to protect skin on the portion of the newborn'"'"'s hand or foot that is received by the cavity, the disposable cover including transparent portions and opaque portions, the transparent portions being configured to allow light to pass between individual sensor pairs, the opaque portions being configured to block light from passing between adjacent sensor pairs.