Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient

• US 9,877,828 B2
• Filed: 05/12/2015
• Issued: 01/30/2018
• Est. Priority Date: 02/26/2008
• Status: Active Grant

• Current Assignee: JenaValve Technology, Inc.
• Original Assignee: JenaValve Technology, Inc.
• Inventors: Straubinger, Helmut, Jung, Johannes
• Primary Examiner(s): Woo, Julian W
• Application Number:
  US14/709,909
• Publication Number:
  US 20150342732A1
• Time in Patent Office: 994 Days
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0023 triangular
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

The present invention relates to a stent (10) for the positioning and anchoring of a valvular prosthesis (100) in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis (100) fastened to a stent (10) will occur relative the stent (10) in the implanted state of the stent (10), even given the peristaltic motion of the heart, the stent (10) according to the invention comprises at least one fastening portion (11) via which the valvular prosthesis (100) is connectable to the stent (10). The stent (10) further comprises positioning arches (15) and retaining arches (16), whereby at least one positioning arch (15) is connected to at least one retaining arch (16) via a first connecting land (17). The stent (10) moreover comprises at least one auxiliary retaining arch (18) which connects the respective arms (16′, 16″) of the at least one retaining arch (16) connected to the at least one positioning arch (15).

Claims

1. An expandable stent comprising:

a plurality of first arches, each first arch having an apex pointing in a proximal direction;

a plurality of second arches, each second arch having an apex opposite an open end portion, the apex of each second arch being axially aligned, in a longitudinal direction of the expandable stent, with the apex of a corresponding first arch, and the open end portion of each second arch being joined to an open end portion of the corresponding first arch;

a plurality of third arches, each third arch corresponding to, and circumferentially interspaced between, two adjacent second arches; and

a valve prosthesis attached to a segment of each second arch distal to the plurality of third arches;

wherein the stent is configured for implantation relative to a native valve comprising a plurality of native valve leaflets, such that the apex of each first arch is positioned in a corresponding pocket of the native valve and wherein each third arch includes an apex pointing in the proximal direction.

2. The expandable stent of claim 1, wherein the apex of each second arch points in the proximal direction.

3. The expandable stent of claim 1, comprising exactly three first arches, exactly three second arches, and exactly three third arches.

4. The expandable stent of claim 1, wherein the segment of each second arch defines a plurality of apertures.

5. The expandable stent of claim 4, wherein each third arch is proximal to at least one aperture defined by at least one of the second arches.

6. The expandable stent of claim 1, wherein the apex of each first arch includes a radiopaque marker.

7. The expandable stent of claim 1, wherein the open end portion of each second arch is joined to the open end portion of each first arch by a strut parallel to a longitudinal axis of the stent.

8. The expandable stent of claim 1, further comprising a plurality of head portions configured for removable attachment to a delivery device, each head portion connected to two adjacent first arches by a strut.

9. The expandable stent of claim 8, wherein each head portion defines an aperture, and wherein each head portion is located at a distal-most end of the stent.

10. The expandable stent of claim 1, wherein each first arch is configured to be positioned on a first side of one of the native valve leaflets, and each second arch is configured to be positioned on a second side of the native valve leaflet, each native valve leaflet being positioned radially inward of at least a portion of the plurality of first arches and radially outward of at least a portion of the plurality of second arches when the expandable stent is implanted.

11. The expandable stent of claim 1, wherein the stent is self-expandable.

12. The expandable stent of claim 1, wherein each second arch includes two apices opposite the open end portion of the second arch.

13. An expandable stent comprising:

a plurality of first arches;

a plurality of second arches, each second arch having an apex opposite an open end portion, the apex of each second arch being axially aligned, in a longitudinal direction of the expandable stent, with an apex of a corresponding first arch, and the open end portion of each second arch being joined to an open end portion of the corresponding first arch, wherein the apex of each first arch and the apex of each second arch point in a proximal direction;

a plurality of third arches, each third arch corresponding to, and circumferentially interspaced between, two adjacent second arches and having an apex pointing in the proximal direction; and

a valve prosthesis attached to each second arch;

wherein the stent is configured for implantation relative to a native valve comprising a plurality of native valve leaflets, a proximal end of the stent being closer to a native heart than a distal end of the stent when the stent is implanted.

14. The expandable stent of claim 13, wherein the open end portion of each second arch is joined to the open end portion of each first arch by a first strut parallel to a longitudinal axis of the stent.

15. The expandable stent of claim 14, further comprising a plurality of head portions, wherein each head portion is connected to two adjacent first arches by a second strut.

16. The expandable stent of claim 13, wherein the valve prosthesis is sutured to each second arch through a plurality of apertures defined by each second arch.

17. The expandable stent of claim 16, wherein at least one aperture defined by each second arch is distal to each third arch.

18. An expandable stent comprising:

a plurality of first arches, each first arch having an apex pointing in a proximal direction towards a native heart upon implantation relative to a native cardiac valve;

a plurality of second arches, each second arch having an apex opposite an open end portion, the apex of each second arch being axially aligned, in a longitudinal direction of the expandable stent, with an apex of a corresponding first arch, and the open end portion of each second arch being joined to an open end portion of the corresponding first arch;

a plurality of third arches, each third arch corresponding to, and circumferentially interspaced between, two adjacent second arches and having an apex pointing in the proximal direction;

a plurality of head portions at a distal end of the expandable stent, each head portion defining an aperture; and

a valve prosthesis attached to each second arch.

19. The expandable stent of claim 18, wherein each head portion is connected to two adjacent first arches by a strut, the plurality of head portions being configured for removable attachment to a delivery device.

20. The expandable stent of claim 18, comprising exactly three third arches.