Medicament delivery device, capsule and in vivo medicine delivery or diagnostic system
First Claim
Patent Images
1. A medicament delivery device, comprising:
- a housing configured for ingestion by a patient and comprising a first part and a second part secured to the first part, an inner surface of the first part and an inner surface of the second part defining an interior volume of the housing;
a flexible wall having an outer periphery, wherein;
the flexible wall is secured between the first part and the second part proximate the outer periphery such that, proximate the outer periphery, the flexible wall is fixed relative to the first part and the second part, the flexible wall separates the interior volume of the housing into a first compartment defined by the first part of the housing and the flexible wall and a second compartment defined by the second part of the housing and the flexible wall, and the flexible wall seals the first compartment of the interior volume relative to the second compartment of the interior volume;
a reservoir disposed in the first compartment of the interior volume of the housing;
a piston disposed in the second compartment of the interior volume of the housing; and
a driving mechanism disposed in the second compartment of the interior volume of the housing, configured to press the piston against the flexible wall to cause the substance to be released from the reservoir through an opening into a gastrointestinal tract of the patient.
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Abstract
A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.
21 Citations
17 Claims
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1. A medicament delivery device, comprising:
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a housing configured for ingestion by a patient and comprising a first part and a second part secured to the first part, an inner surface of the first part and an inner surface of the second part defining an interior volume of the housing;
a flexible wall having an outer periphery, wherein;the flexible wall is secured between the first part and the second part proximate the outer periphery such that, proximate the outer periphery, the flexible wall is fixed relative to the first part and the second part, the flexible wall separates the interior volume of the housing into a first compartment defined by the first part of the housing and the flexible wall and a second compartment defined by the second part of the housing and the flexible wall, and the flexible wall seals the first compartment of the interior volume relative to the second compartment of the interior volume;
a reservoir disposed in the first compartment of the interior volume of the housing;
a piston disposed in the second compartment of the interior volume of the housing; anda driving mechanism disposed in the second compartment of the interior volume of the housing, configured to press the piston against the flexible wall to cause the substance to be released from the reservoir through an opening into a gastrointestinal tract of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 15, 17)
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7. A medicament delivery device for delivering a substance inside a body, the device comprising:
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a housing configured as an elongate capsule comprising a sidewall formed about a longitudinal axis, the sidewall having a diameter smaller than a length measured along the longitudinal axis of the capsule, the capsule adapted for complete insertion into a user'"'"'s body and defining a dispensing hole, the housing comprising a first part and a second part secured to the first part, the first part comprising a first portion of the sidewall and the second part comprising a second portion of the sidewall;
a flexible wall secured between the first portion of the sidewall and the second portion of the sidewall proximate an outer periphery of the flexible wall such that the outer periphery of the flexible wall is fixed relative to the first part and the second part, theflexible wall extending across the entirety of an inner diameter of the housing to separate the housing into a first compartment and a second compartment and forming a seal between the first compartment and the second compartment, the first compartment comprising a reservoir formed by a portion of the housing including the dispensing hole and the flexible wall; and a driving mechanism disposed in the second compartment to displace the flexible wall toward the first compartment, causing at least a portion of the substance to be released from the reservoir through the dispensing hole, wherein the driving mechanism comprises an actuatable piston adapted to press against the flexible wall. - View Dependent Claims (8, 9, 10, 11, 13)
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12. A capsule for delivering a substance inside a body, the capsule comprising:
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a housing comprising a first part and a second part secured to the first part, the housing comprising a sidewall extending between opposite ends defining an internal volume and configured as a generally elongate capsule for complete insertion into a bodily lumen, the elongate capsule having a length along a longitudinal axis greater than a diameter of the capsule, normal the longitudinal axis, and the internal volume having an internal circumference normal to the longitudinal axis; a flexible wall in the housing having an outer circumference conforming to the internal circumference of the internal volume of the housing, the flexible wall being secured, proximate the outer circumference, between the first part of the housing and the second part of the housing at the sidewall such that the flexible wall is fixed relative to the first part and the second, part proximate the sidewall, the flexible wail completely partitioning the internal volume of the capsule into a first compartment comprising a reservoir on a first side of the flexible wall, along the longitudinal axis, and a second compartment on a second side of the flexible wall, along the longitudinal axis, and the flexible wall sealing the first compartment relative to the second compartment;
a driving mechanism disposed in the second compartment and configured to press against the flexible wall, causing the flexible wall to displace in a direction toward the reservoir to reduce a volume of the reservoir;
control circuitry disposed in the second compartment and configured to operate the driving mechanism, anda power source disposed in the second compartment fbr providing power to at least one of the control circuitry and the driving mechanism. - View Dependent Claims (14, 16)
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Specification