Entrainment of bioelectrical brain signals
First Claim
1. A method comprising:
- delivering the electrical stimulation from a medical device at a first frequency to a brain of a patient when bioelectrical brain signals of the patient oscillate at a second frequency, wherein the second frequency corresponds to pathological brain signals of the patient, and wherein the electrical stimulation is selected to entrain the bioelectrical brain signals of the patient; and
adjusting the delivered electrical stimulation from the first frequency to a third frequency while the bioelectrical brain signals are entrained by the electrical stimulation, wherein adjusting the delivered electrical stimulation changes the bioelectrical brain signal oscillations to a fourth frequency different from the second frequency.
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Abstract
The disclosure relates to the delivery of electrical stimulation therapy to the brain of a patient, e.g., to treat or otherwise manage a patient disorder. In one example, the disclosure relates to a method comprising generating electrical stimulation via a medical device; delivering the electrical stimulation at a first frequency to a brain of a patient when the bioelectrical brain signals of the patient oscillate at a second frequency, where the second frequency corresponds to pathological brain signals of the patient, where the electrical stimulation is selected to entrain the bioeiectrical brain signals of the patient; and adjusting the delivered electrical stimulation from the first frequency to a third frequency, where adjusting the delivered electrical stimulation changes the bioelectrical brain signal oscillations to a fourth frequency different from the second frequency. The fourth frequency may correspond to an oscillation frequency of non-pathological brain signals of the patient.
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Citations
28 Claims
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1. A method comprising:
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delivering the electrical stimulation from a medical device at a first frequency to a brain of a patient when bioelectrical brain signals of the patient oscillate at a second frequency, wherein the second frequency corresponds to pathological brain signals of the patient, and wherein the electrical stimulation is selected to entrain the bioelectrical brain signals of the patient; and adjusting the delivered electrical stimulation from the first frequency to a third frequency while the bioelectrical brain signals are entrained by the electrical stimulation, wherein adjusting the delivered electrical stimulation changes the bioelectrical brain signal oscillations to a fourth frequency different from the second frequency. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A medical device system comprising:
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an electrical stimulation generator configured to generate electrical stimulation; and a processor configured to control the electrical stimulation generator to generate and deliver the electrical stimulation at a first frequency to a brain of a patient when bioelectrical brain signals of the patient oscillate at a second frequency, wherein the second frequency corresponds to pathological brain signals of the patient, wherein the electrical stimulation is selected to entrain the bioelectrical brain signals of the patient, and adjust the delivered electrical stimulation from the first frequency to a third frequency while the bioelectrical brain signals are entrained by the electrical stimulation, wherein adjusting the delivered electrical stimulation changes the oscillation of the bioelectrical brain signal oscillations to a fourth frequency different from the second frequency. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A system comprising:
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means for delivering the electrical stimulation at a first frequency to a brain of a patient when bioelectrical brain signals of the patient oscillate at a second frequency, wherein the second frequency corresponds to pathological brain signals of the patient, wherein the electrical stimulation is selected to entrain the bioelectrical brain signals of the patient; and means for adjusting the delivered electrical stimulation from the first frequency to a third frequency while the bioelectrical brain signals are entrained by the electrical stimulation, wherein the means for adjusting the delivered electrical stimulation changes the bioelectrical brain signal oscillations to a fourth frequency different from the second frequency.
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28. A non-transitory computer-readable storage medium comprising instructions that cause one or more processors to:
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control delivery of the electrical stimulation at a first frequency to a brain of a patient when bioelectrical brain signals of the patient oscillate at a second frequency, wherein the second frequency corresponds to pathological brain signals of the patient, wherein the electrical stimulation is selected to entrain the bioelectrical brain signals of the patient; and adjust the delivered electrical stimulation from the first frequency to a third frequency while the bioelectrical brain signals are entrained by the electrical stimulation, wherein adjusting the delivered electrical stimulation changes the bioelectrical brain signal oscillations to a fourth frequency different from the second frequency.
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Specification