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Efficient modulated imaging

  • US 9,883,803 B2
  • Filed: 11/11/2014
  • Issued: 02/06/2018
  • Est. Priority Date: 11/07/2012
  • Status: Active Grant
First Claim
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1. A method for measurement of a turbid sample, the method comprising the steps of:

  • illuminating with a first light source a target area of the turbid sample with only spatially structured at a plurality of wavelengths and along a first optical projection path,collecting light reflected from the turbid sample to obtain remitted spatially structured light of the sample at a first plurality of wavelengths, λ

    j,illuminating with a second light source the target area of the turbid sample with only planar structured light at a plurality of wavelengths and along a second optical projection path, wherein the first optical projection path differs from the second optical projection path,collecting light reflected from the turbid sample to obtain remitted planar structured light of the sample at a second plurality of wavelengths, λ

    k, andcombining measurements of the remitted spatially structured light and the remitted planar light collected from the turbid sample to obtain fit parameters, wherein the fit parameters include one or more optical properties of the turbid sample at the first and second plurality of wavelengths, λ

    j and λ

    k, and a concentration of absorbing or fluorescent molecules.

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