Atrial appendage blood filtration systems
First Claim
1. A device configured for implantation in a left atrial appendage, the device comprising:
- a support structure having a proximal end, a distal end, and an intermediate portion extending between the proximal end and the distal end,wherein in an unconstrained condition diameters of the respective proximal end, distal end and intermediate portion of the support structure decrease distally over its longitudinal axis;
a membrane extending along the intermediate portion and supported by the proximal end of the support structure,wherein the membrane is in a generally planar configuration along a plane at the proximal end of the support structure; and
a plurality of tissue-engaging anchors disposed on the support structure distal of the membrane.
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Accused Products
Abstract
Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. A compressed filter device attached to a tether wire is loaded in the delivery tube. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. A filter membrane in the deployed device extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.
171 Citations
20 Claims
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1. A device configured for implantation in a left atrial appendage, the device comprising:
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a support structure having a proximal end, a distal end, and an intermediate portion extending between the proximal end and the distal end, wherein in an unconstrained condition diameters of the respective proximal end, distal end and intermediate portion of the support structure decrease distally over its longitudinal axis; a membrane extending along the intermediate portion and supported by the proximal end of the support structure, wherein the membrane is in a generally planar configuration along a plane at the proximal end of the support structure; and a plurality of tissue-engaging anchors disposed on the support structure distal of the membrane. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A system for implanting an implant in a left atrial appendage, the system
comprising: -
a delivery catheter having an elongate flexible body with a proximal end and a distal end; a wire extending through the delivery catheter; an implant comprising; a support structure having a proximal end, a distal end, and an intermediate portion extending between the proximal end and the distal end, wherein in an unconstrained condition diameters of the support structure decrease distally over its longitudinal axis; a membrane extending along the intermediate portion and supported by the proximal end of the support structure; and a plurality of tissue-engaging anchors disposed on the support structure distal of the membrane, wherein the membrane is in a generally planar configuration along a plane at the proximal end of the support structure; and wherein a distal end of the wire is configured to be releasably attached to a proximal end of the implant. - View Dependent Claims (14, 15, 16, 17)
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18. A blood filtration device for filtering blood flow from an atrial appendage, comprising:
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a proximal hub including a protrusion; a one-piece frame having a proximal end, a proximal portion, a distal portion, an intermediate portion between the proximal portion and the distal portion, and a distal end, wherein in an unconstrained condition diameters of the support structure decrease distally over its longitudinal axis; a blood-permeable membrane or mesh covering the proximal portion and at least a portion of the intermediate portion of the one-piece frame such that the blood-permeable membrane or mesh presents a generally planar surface; and a plurality of tissue-engaging anchors disposed on the support structure distal of the blood-permeable membrane, wherein the protrusion extends proximally from the generally planar surface. - View Dependent Claims (19, 20)
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Specification