Intrascleral shunt placement

• US 9,883,969 B2
• Filed: 01/25/2016
• Issued: 02/06/2018
• Est. Priority Date: 12/08/2011
• Status: Active Grant

• Current Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Original Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Inventors: Horvath, Christopher, Romoda, Laszlo O., Anderson, Cory
• Primary Examiner(s): MARCETICH, ADAM M
• Application Number:
  US15/005,954
• Publication Number:
  US 20160135993A1
• Time in Patent Office: 743 Days
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2009/00861 adapted for treatment at a particular location
• CPC Class Codes: A61F 2009/00865 Sclera
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/00736 Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments A61F9/008 takes precedence
• CPC Class Codes: A61F 9/00763 with rotating or reciprocating cutting elements, e.g. concentric cutting needles atherectomy cutting instruments A61B17/3207; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 2210/0612 Eyes
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202

Abstract

Glaucoma can be treated by implanting an intraocular shunt into an eye. The eye has an anterior chamber and sclera. A shunt can be placed into the eye to establish fluid communication from the anterior chamber of the eye through the sclera.

Claims

1. A method comprising inserting, through a cornea, an implant in an eye having (i) an anterior chamber and (ii) a sclera, to form a channel through the sclera and thereby establish fluid communication between the anterior chamber and the channel.

2. The method of claim 1, wherein the implant comprises an intraocular shunt, and wherein the inserting comprises inserting the intraocular shunt through the cornea and into the anterior chamber.

3. The method of claim 1, wherein the inserting comprises, from within the anterior chamber, forming a slit in sclera.

4. The method of claim 1, wherein the inserting comprises inserting, through the cornea and into the anterior chamber, a hollow shaft carrying an intraocular shunt.

5. The method of claim 4, further comprising, from within the anterior chamber, piercing the sclera with the shaft such that a distal tip of the shaft enters the sclera to form the channel.

6. The method of claim 5, wherein the inserting comprises, while maintaining the shaft distal tip positioned in the sclera, advancing the shunt from the hollow shaft to position a first end of the shunt in the anterior chamber and a second end of the shunt between layers of sclera such that the shunt forms a passage from the anterior chamber to the sclera.

7. The method of claim 1, wherein the inserting comprises positioning an outlet end of a shunt between layers of sclera for providing fluid communication to a space between the layers.

8. The method of claim 7, further comprising actuating a portion of a deployment device to distally advance the shunt into the space.

9. The method of claim 1, wherein the inserting comprises advancing a pusher component to distally advance the implant into the sclera.

10. The method of claim 9, wherein the advancing the pusher component comprises rotating a portion of a deployment mechanism.

11. A method comprising inserting an intraocular shunt through a cornea of an eye, and positioning an outlet end of the shunt in a channel formed within sclera and an inlet end of the shunt in an anterior chamber of the eye.

12. The method of claim 11, further comprising forming the channel in the sclera using a hollow shaft of a deployment mechanism.

13. The method of claim 11, further comprising, from within the anterior chamber, forming a slit in sclera.

14. The method of claim 13, wherein the positioning comprises positioning the outlet end in the slit.

15. The method of claim 11, wherein the positioning comprises positioning the shunt outlet end in the sclera between deep and superficial layers of sclera.

16. The method of claim 11, wherein the positioning comprises advancing a pusher component to distally advance the shunt into the sclera.

17. The method of claim 16, wherein the advancing the pusher component comprises rotating a portion of a deployment mechanism.

18. A method comprising piercing a cornea of an eye with a hollow shaft, advancing the shaft to form a channel through sclera, and positioning an outlet end of a shunt within the channel without contacting the outlet end with conjunctiva and an inlet end of the shunt within an anterior chamber of the eye to diffuse fluid from the anterior chamber via subconjunctival drainage and episcleral lymphatic pathways.

19. The method of claim 18, further comprising actuating a portion of a deployment device to distally advance the shunt into the channel.

20. The method of claim 19, wherein the actuating comprises rotating the portion of the deployment device.

21. The method of claim 20, wherein the rotating causes distal advancement of a pusher component to distally advance the shunt into the sclera.

22. The method of claim 18, wherein the channel terminates in the sclera.

23. The method of claim 18, wherein the positioning comprises maintaining a hollow shaft distal tip positioned in the sclera while simultaneously advancing the shunt from the hollow shaft to position the outlet end of the shunt between layers of sclera.

24. The method of claim 18, further comprising, from within the anterior chamber, forming a slit in sclera.

25. The method of claim 18, wherein after the positioning, the outlet end of the shunt is spaced apart from the conjunctiva.

26. A method comprising inserting, through a cornea, an implant into an eye to establish a diffusion pathway from an anterior chamber of the eye to subconjunctival drainage and episcleral lymphatic pathways without contacting the implant with conjunctiva.

27. The method of claim 26, wherein the pathway terminates in sclera.

28. The method of claim 26, wherein the inserting comprises positioning an outlet end of the implant between layers of sclera for providing fluid communication to a space between the layers.

29. The method of claim 26, wherein after the inserting, an outlet end of the implant is spaced apart from the conjunctiva.