Reconstituting infusion device
First Claim
1. A device for mixing and delivering a medicament into the body of a patient by injection into or through the skin of a patient, comprising:
- a housing having a bottom surface adapted to contact the skin of a patient, and a top surface wherein said housing has a body opening having a longitudinal axis;
an injection needle adapted for penetration of tissue, said needle having a lumen;
a reservoir disposed within said housing forming a first chamber for containing a first substance, said reservoir being in selective fluid communication with the lumen of the injection needle, wherein said first reservoir comprises a flexible, non-distending film;
a pressurizing system for pressurizing said first chamber when the device is activated;
a cartridge assembly insertable into said body opening along said longitudinal axis said cartridge assembly having;
a barrel having first and second ends wherein at least said first end is open; and
a pierceable stopper, disposed in within said barrel open end, and adapted for sealing said first end, said stopper being translatable within said barrel between a first position substantially at said first end, and a second position substantially at said second end;
wherein said barrel and stopper form a second chamber for containing a second substance; and
a selective fluid communication valve disposed in said body opening wherein the selective fluid communication valve is adapted for selective fluidic communication with said first chamber and is adapted for selective communication with said second chamber;
wherein when said stopper is in said first position, said second substance is substantially within said second chamber, and when said stopper is in said second position, said second substance is substantially within said first chamber and co-mingled with said first substance for forming said medicament for infusion into the patient.
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Accused Products
Abstract
A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.
61 Citations
12 Claims
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1. A device for mixing and delivering a medicament into the body of a patient by injection into or through the skin of a patient, comprising:
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a housing having a bottom surface adapted to contact the skin of a patient, and a top surface wherein said housing has a body opening having a longitudinal axis; an injection needle adapted for penetration of tissue, said needle having a lumen; a reservoir disposed within said housing forming a first chamber for containing a first substance, said reservoir being in selective fluid communication with the lumen of the injection needle, wherein said first reservoir comprises a flexible, non-distending film; a pressurizing system for pressurizing said first chamber when the device is activated; a cartridge assembly insertable into said body opening along said longitudinal axis said cartridge assembly having; a barrel having first and second ends wherein at least said first end is open; and a pierceable stopper, disposed in within said barrel open end, and adapted for sealing said first end, said stopper being translatable within said barrel between a first position substantially at said first end, and a second position substantially at said second end; wherein said barrel and stopper form a second chamber for containing a second substance; and a selective fluid communication valve disposed in said body opening wherein the selective fluid communication valve is adapted for selective fluidic communication with said first chamber and is adapted for selective communication with said second chamber; wherein when said stopper is in said first position, said second substance is substantially within said second chamber, and when said stopper is in said second position, said second substance is substantially within said first chamber and co-mingled with said first substance for forming said medicament for infusion into the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A device for mixing and delivering a medicament into the body of a patient by injection into or through the skin of a patient, comprising:
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a housing having a bottom surface adapted to contact the skin of a patient, and a top surface wherein said housing has a body opening having a longitudinal axis; an injection needle adapted for penetration of tissue, said needle having a lumen; a reservoir disposed within said housing forming a first chamber for containing a first substance, said reservoir being in selective fluid communication with the lumen of the injection needle; a pressurizing system for pressurizing said first chamber when the device is activated; a cartridge assembly insertable into said body opening along said longitudinal axis said cartridge assembly having; a barrel having first and second ends wherein at least said first end is open; and a pierceable stopper, disposed in within said barrel open end, and adapted for sealing said first end, said stopper being translatable within said barrel between a first position substantially at said first end, and a second position substantially at said second end; wherein said barrel and stopper form a second chamber for containing a second sub stance; a selective fluid communication valve disposed in said body opening wherein the selective fluid communication valve is adapted for selective fluidic communication with said first chamber and is adapted for selective communication with said second chamber; and a removable retaining pin, preventing pressurization of the first chamber until the retaining pin is removed; wherein when said stopper is in said first position, said second substance is substantially within said second chamber, and when said stopper is in said second position, said second substance is substantially within said first chamber and co-mingled with said first substance for forming said medicament for infusion into the patient.
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12. A device for mixing and delivering a medicament into the body of a patient by injection into or through the skin of a patient, comprising:
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a housing having a bottom surface adapted to contact the skin of a patient, and a top surface wherein said housing has a body opening having a longitudinal axis; an injection needle adapted for penetration of tissue, said needle having a lumen; a reservoir disposed within said housing forming a first chamber for containing a first substance, said reservoir being in selective fluid communication with the lumen of the injection needle; a pressurizing system for pressurizing said first chamber when the device is activated; a cartridge assembly insertable into said body opening along said longitudinal axis said cartridge assembly having; a barrel having first and second ends wherein at least said first end is open; and a pierceable stopper, disposed in within said barrel open end, and adapted for sealing said first end, said stopper being translatable within said barrel between a first position substantially at said first end, and a second position substantially at said second end; wherein said barrel and stopper form a second chamber for containing a second sub stance; a selective fluid communication valve disposed in said body opening wherein the selective fluid communication valve is adapted for selective fluidic communication with said first chamber and is adapted for selective communication with said second chamber; and a patient-depressible button slide for activating the device, said button slide having a button slide opening; wherein when said stopper is in said first position, said second substance is substantially within said second chamber, and when said stopper is in said second position, said second substance is substantially within said first chamber and co-mingled with said first substance for forming said medicament for infusion into the patient; wherein said injection needle is biased toward the bottom surface by a biasing member and released to extend from said bottom surface as the button slide is depressed to align the button slide opening with the injection needle.
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Specification