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Multisignal labeling reagents and processes and uses therefor

  • US 9,884,889 B2
  • Filed: 09/03/2015
  • Issued: 02/06/2018
  • Est. Priority Date: 04/03/2003
  • Status: Expired due to Term
First Claim
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1. A multisignal labeling reagent comprising:

  • (i) an oligomer of nucleotides or nucleotide analogs;

    (ii) a plurality of DNA supramolecular binding molecules noncovalently bound to the oligomer,wherein said DNA supramolecular binding molecules comprise a detectable label attached thereto that is not a DNA supramolecular binding molecule, andwherein said DNA supramolecular binding molecules are selected from minor groove binders and major groove binders; and

    (iii) a first reactive group covalently bound to the oligomer, ora first partner of a first binding pair covalently bound to the oligomer.

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