Neural injection system and related methods

• US 9,888,940 B2
• Filed: 03/15/2013
• Issued: 02/13/2018
• Est. Priority Date: 09/11/2006
• Status: Active Grant

• Current Assignee: Custom Medical Applications
• Original Assignee: Custom Medical Applications
• Inventors: Racz, N. Sandor
• Primary Examiner(s): Price, Nathan R
• Assistant Examiner(s): Zamory, Justin L
• Application Number:
  US13/840,426
• Publication Number:
  US 20130211383A1
• Time in Patent Office: 1,796 Days
• CPC Class Codes: A61B 17/3401 Puncturing needles for the peridural or subarachnoid space or the plexus, e.g. for anaesthesia local anaesthesia A61M19/00
• CPC Class Codes: A61B 17/3415 for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters A61B17/3417 takes precedence; body piercing catheter guide needles A61M25/06
• CPC Class Codes: A61B 17/3496 Protecting sleeves or inner probes; Retractable tips for protecting body piercing guide needles A61M25/0612
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61M 19/00 Local anaesthesia syringes therefor A61M5/00; Hypothermia A61M5/42 takes precedence; cooling blood in a bypass of the arterial system A61M1/36
• CPC Class Codes: A61M 2025/0089 Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 5/3291 Shafts with additional lateral openings
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence

Abstract

A novel neural injection system and related methods are herein disclosed. Various embodiments of an embodiment of a neural injection system of the present invention provide for at least one benefit of enhanced injection characteristics, increased operational efficiency, reduced cost per unit, reduced incidence of injury through intraneural/intravascular injection, reduced incidence of injury through pricking/piercing, and/or the like.

Claims

1. A method for administering a medicament to a subject comprising:

locating a site for injection;

inserting at least a portion of a neural injection system into the subject, without use of a separate introducer needle, the inserting comprising;

inserting an at least partially hollow cannula being defined by a first inside diameter, a first outside diameter, and a first length, and a side port located coaxially along a lateral axis of the cannula for fluid communication from inside said at least partially hollow cannula to outside said at least partially hollow cannula into the subject, a terminal end of the cannula comprising an opening separate and spaced from the side port along a longitudinal axis of the cannula, wherein the terminal end of the cannula comprises a blunt tapered end, the blunt tapered end of the cannula acting as an introducer needle to make a slit and/or hole to provide access to tissue of a subject;

inserting a stylet through the entire length of the cannula and releasably locking the stylet in a first position within the cannula; and

extending the stylet through the entire length of the cannula, through the opening at the terminal end of the cannula, and longitudinally past, along the longitudinal axis of the cannula, the opening in order to access tissue of the subject that is spaced from and positioned longitudinally past the terminal end of the cannula; and

injecting the medicament into the subject.

2. The method of claim 1, wherein injecting the medicament into the subject comprises causing a therapeutic amount of the medicament to ooze multidirectionally from a distal portion of the neural injection system into tissue of the subject.

3. The method of claim 1, further comprising preparing the subject for administering a medicament.

4. The method of claim 3, wherein preparing the subject for administration of a medicament comprises placing the subject'"'"'s head in a neutral position.

5. The method of claim 1, further comprising stimulating a tissue about the site.

6. The method of claim 5, wherein stimulating said tissue comprises ablating at least a portion of said tissue.

7. The method of claim 1, further comprising probing a tissue.

8. The method of claim 1, wherein the medicament is anesthesia.

9. The method of claim 1, further comprising injecting the medicament into a particular tissue of the subject.

10. The method of claim 9, further comprising injecting the medicament into an internal organ.

11. The method of claim 10, further comprising injecting the medicament into a wall of a beating heart.

12. The method of claim 1, wherein the medicament is a therapeutic agent.

13. The method of claim 1, wherein the medicament is a nucleic acid.

14. A neural injection system comprising:

an at least partially hollow cannula being defined by a first inside diameter, a first outside diameter, and a first length, and a side port located coaxially along a lateral axis of the cannula for fluid communication from inside said at least partially hollow cannula to outside said at least partially hollow cannula, a terminal end of the cannula comprising an opening separate and spaced from the side port along a longitudinal axis of the cannula, wherein the terminal end of the cannula comprises a blunt tapered end, the tapered distal end of the cannula configured for use as an introducer to make a slit and/or hole to provide access to tissue of a subject; and

a stylet, wherein the stylet is capable of being releasably locked in a first position within said cannula, wherein the cannula is configured to receive the stylet along the entire length of the cannula, wherein the stylet is configured to be inserted through the entire length of the cannula, through the opening at the terminal end of the cannula, and longitudinally past, along the longitudinal axis of the cannula, the opening in order to access tissue of the subject that is spaced from and positioned longitudinally past the terminal end of the cannula.

15. The neural injection system of claim 14, wherein the stylet further comprises a side port.

16. The neural injection system of claim 14, wherein the stylet is retractable.

17. A neural injection system comprising:

an at least partially hollow cannula comprising a side port located coaxially along a lateral axis of the cannula for fluid communication from inside the at least partially hollow cannula to outside the at least partially hollow cannula, a terminal end of the cannula comprising an opening separate and spaced from the side port along a longitudinal axis of the cannula, wherein the terminal end of the cannula comprises a blunt tapered end, the tapered distal end of the cannula configured for use as an introducer needle for providing access to tissue of a subject; and

a stylet comprising a solid terminal end, wherein the stylet is capable of being releasably locked in a position within the cannula, wherein the cannula is configured to receive the stylet along the entire length of the cannula, wherein the stylet is configured to be inserted through the entire length of the cannula, through the opening at the terminal end of the cannula, and longitudinally past, along the longitudinal axis of the cannula, the opening in order to access tissue of the subject with the solid terminal end of the stylet that is spaced from and positioned longitudinally past the terminal end of the cannula.