Methods for use of sex sorted semen to improve genetic management in swine

• US 9,888,990 B2
• Filed: 11/26/2013
• Issued: 02/13/2018
• Est. Priority Date: 06/06/2012
• Status: Active Grant

• Current Assignee: Inguran LLC
• Original Assignee: Inguran LLC
• Inventors: van der Steen, Hein, BeVier, Gregg
• Primary Examiner(s): Noble, Marcia S
• Application Number:
  US14/090,979
• Publication Number:
  US 20140142421A1
• Time in Patent Office: 1,540 Days
• CPC Class Codes: A61B 1/044 for absorption imaging
• CPC Class Codes: A61B 1/3132 for laparoscopy
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 6/485 involving fluorescence X-ray imaging
• CPC Class Codes: A61D 19/027 Devices for injecting semen into animals, e.g. syringes, guns, probes
• CPC Class Codes: A61K 35/52 Sperm; Prostate; Seminal fluid; Leydig cells of testes

Abstract

The invention relates to methods of increasing genetic merit of swine by establishing a plurality of mating subtypes for a line of swine, and determining a percentage of progeny that are male for each of the mating subtypes, or a percentage of progeny that are female for each of the mating subtypes, that would result, relative to a control, in an increase in genetic merit in the line; the invention further relates to sorting a sperm cell sample from a male swine in one of the mating subtypes into one or more subpopulations of sperm cells, wherein a majority of sperm cells in a subpopulation of sperm cells bear X chromosomes or Y chromosomes, and inseminating one or more female swine in the one of the mating subtypes with the subpopulation of sperm cells to achieve the percentage of progeny that are male, or the percentage of progeny that are female, determined to increase genetic merit relative to the control.

Claims

1. A method of increasing genetic merit of swine comprising the steps of:

providing a population of swine;

establishing a subpopulation of males and females from the population of swine available for breeding and parenting progeny;

establishing female subgroups in the subpopulation, or male subgroups in the subpopulation, wherein the female subgroups are established based on genetic merit or parity and the male subgroups are established based on genetic merit or age, and each female subgroup comprises one or more females and each male subgroup comprises one or more males;

establishing a mating subtype, wherein the mating subtype comprises i) a female subgroup and one or more males from the subpopulation or ii) a male subgroup and one or more females from the subpopulation;

determining a percentage of male progeny for the mating subtype, or a percentage of female progeny for the mating subtype, that would result in an increase in genetic merit in the next generation relative to a control, wherein in the control, approximately 50% of progeny are male; and

inseminating one or more females in the mating subtype with a sex sorted sperm cell sample from a male in the mating subtype to achieve the percentage of progeny that are male, or the percentage of progeny that are female, determined to increase genetic merit relative to the control.

2. The method of claim 1, wherein the percentage of male progeny, or the percentage of female progeny, determined to increase genetic merit in the next generation, does not increase inbreeding relative to the control.

3. The method of claim 1, wherein the subpopulation of male and female swine are members of a genetic nucleus, a daughter nucleus or a multiplier.

4. The method of claim 1, wherein subpopulation of male and female swine are members of a genetic nucleus.

5. The method of claim 1, wherein the subpopulation of male and female swine are members of a sire line or dam line.

6. The method of claim 1, wherein in the control, all female swine to be mated are inseminated with unsorted semen samples.

7. The method of claim 5, further comprising the step of producing progeny of the subpopulation wherein approximately 10 to 35% of the progeny are male.

8. The method of claim 7, wherein approximately 15 to 30% of the progeny are male.

9. The method of claim 5, further comprising the step of producing progeny of the subpopulation wherein approximately 5 to 30% of the progeny are male.

10. The method of claim 9, wherein approximately 10 to 25% of the progeny are male.

11. The method of claim 1, further comprising the step of producing progeny of the subpopulation wherein approximately 0 to 10% or approximately 90 to 100% of the progeny are male or female and are members of a daughter nucleus or a multiplier.

12. The method of claim 1, wherein the percentages are determined using a stochastic or a deterministic method.