Detachable module for recharging sorbent materials with optional bypass

• US 9,895,477 B2
• Filed: 04/25/2014
• Issued: 02/20/2018
• Est. Priority Date: 11/26/2013
• Status: Active Grant

• Current Assignee: Mozarc Medical US LLC
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Pudil, Bryant J., Gerber, Martin T., Lura, David B., Meyer, Thomas E.
• Primary Examiner(s): GURTOWSKI, RICHARD C
• Application Number:
  US14/261,651
• Publication Number:
  US 20150306292A1
• Time in Patent Office: 1,397 Days
• Field of Search: None
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: B01J 20/00 Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
• CPC Class Codes: B01J 20/0211 Compounds of Ti, Zr, Hf
• CPC Class Codes: B01J 20/0292 Phosphates of compounds other than those provided for in B01J20/048
• CPC Class Codes: B01J 20/06 comprising oxides or hydroxides of metals not provided for in group B01J20/04
• CPC Class Codes: B01J 20/08 comprising aluminium oxide or hydroxide; comprising bauxite
• CPC Class Codes: B01J 20/20 comprising free carbon; comprising carbon obtained by carbonising processes
• CPC Class Codes: B01J 20/28052 Several layers of identical or different sorbents stacked in a housing, e.g. in a column
• CPC Class Codes: B01J 20/3433 of sorbents or filter aids other than those covered by B01J20/3408 - B01J20/3425
• CPC Class Codes: B01J 2220/42 Materials comprising a mixture of inorganic materials materials coated or impregnated on a carrier B01J20/32
• CPC Class Codes: B01J 2220/46 Materials comprising a mixture of inorganic and organic materials materials coated or impregnated on a carrier B01J20/32
• CPC Class Codes: B01J 2220/62 In a cartridge
• CPC Class Codes: B01J 39/08 Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
• CPC Class Codes: B01J 39/12 Compounds containing phosphorus

Abstract

A detachable module for optionally recharging sorbent materials, including zirconium phosphate, with an optional bypass and conduits for a sorbent cartridge. The sorbent cartridge can have one or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein recharged.

Claims

1. A sorbent cartridge, comprising at least one rechargeable module containing at least one sorbent material, the rechargeable module rechargeable to restore a functional capacity of the at least one sorbent material, and having one or more connectors fluidly connectable to a second module;

and the rechargeable module fluidly connectable to a recharger wherein the sorbent cartridge is reversibly attachable and detachable to the recharger.

2. The sorbent cartridge of claim 1, wherein the cartridge comprises at least one non-reusable module.

3. The sorbent cartridge of claim 1, wherein the at least one rechargeable module contains multiple sorbent materials.

4. The sorbent cartridge of claim 1, wherein the at least one module is part of a controlled compliant dialysis circuit.

5. The sorbent cartridge of claim 1, wherein the at least one-rechargeable module is detachable from the sorbent cartridge.

6. The sorbent cartridge of claim 1, wherein the at least one rechargeable module is connected with other modules, reusable or non-reusable, wherein the one or more connectors are selected from a group consisting of quick-connect, twist-lock, push-on, and threaded fittings.

7. The sorbent cartridge of claim 1, wherein the one or more connectors comprise a length of tubing and a valve assembly.

8. The sorbent cartridge of claim 1, wherein the sorbent material is selected from a group comprising zirconium phosphate, hydrous zirconium oxide, activated carbon, alumina, urease and ion exchange resin.

9. The sorbent cartridge of claim 1, wherein a fluid flow path flows in a direction through a first module, through a connector, and then through a second module.

10. The sorbent cartridge of claim 1, wherein a fluid flow path flows in a direction through a first module, through a connector, through a second module, through a connector, and then through a third module.

11. The sorbent cartridge of claim 1, wherein a bypass fluid flow path diverts flow from a first module to a third module.

12. The sorbent cartridge of claim 11, wherein the flow is diverted through the bypass fluid flow path using a valve assembly positioned on a connector.

13. The sorbent cartridge of claim 9, wherein the first module contains at least one material selected from the group consisting of hydrous zirconium oxide, alumina, urease, ion exchange resin, zirconium phosphate and activated carbon, and mixtures thereof;

and the second module contains at least one material selected from the group consisting of zirconium phosphate, hydrous zirconium oxide, an ion exchange resin, and mixtures thereof.

14. The sorbent cartridge of claim 13 wherein at least the first module or second module contains the ion exchange resin and wherein the ion-exchange resin is a chelating ion exchange resin.

15. The sorbent cartridge of claim 10, wherein the first module contains at least one material selected from the group consisting of hydrous zirconium oxide, alumina, urease, ion exchange resin, and activated carbon, and mixtures thereof;

and the second module contains at least one material selected from the group consisting of zirconium phosphate, hydrous zirconium oxide, ion exchange resin, alumina and urease, and mixtures thereof; and

the third module contains at least one material selected from the group consisting of activated carbon, zirconium phosphate, ion exchange resin, and hydrous zirconium oxide, and mixtures thereof.

16. The sorbent cartridge of claim 2, wherein the non-reusable module is disposable after use.

17. The sorbent cartridge of claim 1, wherein at least one module has a barcode.

18. The sorbent cartridge of claim 7, wherein the one or more connectors include an access point for a sensor.

19. The sorbent cartridge of claim 1 wherein the one or more connectors is fluidly connectable to a bypass line and/or wash line.

20. The sorbent cartridge of claim 8, wherein the valve assembly is operated under control of a programmable controller or computer system to regulate flow into, out of, and between modules.

21. The sorbent cartridge of claim 7, wherein the valve assembly is operated under control of a programmable controller or computer system to regulate flow into, out of, and between modules.

22. The sorbent cartridge of claim 7, wherein fluid flow through the valve assembly is sensed by any one of a photocell, a flow sensor, or a measuring apparatus.

23. The sorbent cartridge of claim 1, wherein the sorbent cartridge is fluidly connectable to a control pump for circulating fluid in the fluid flow path.

24. The sorbent cartridge of claim 3, wherein the multiple sorbent materials are mixed together.

25. The sorbent cartridge of claim 11, wherein a recharger is positioned on the bypass flow path.

26. The sorbent cartridge of claim 12 wherein flow is diverted into the bypass flow path by use of a valve positioned on a connector after the first module and before the second module.

27. The sorbent cartridge of claim 12 wherein flow is diverted into the bypass flow path by use of a valve positioned on a connector after the second module and before the third module.

28. The sorbent cartridge of claim 10, wherein the first module contains urease, the second module contains zirconium phosphate, and the third module contains zirconium oxide.

29. The sorbent cartridge of claim 28, wherein the first module further comprises activated carbon.

30. The sorbent cartridge of claim 29, wherein the first module comprises a first layer of activated carbon, a second layer of urease downstream of the first layer, and a third layer of activated carbon downstream of the second layer.

31. The sorbent cartridge of claim 1, further comprising at least two rechargeable modules forming a unitary body.

32. The sorbent cartridge of claim 1, further comprising at least three rechargeable modules forming a unitary body.

33. The sorbent cartridge of claim 1, wherein the rechargeable module is a discreet component rigidly attachable to another module.