Multiple imaging mode tissue marker

• US 9,901,415 B2
• Filed: 01/20/2017
• Issued: 02/27/2018
• Est. Priority Date: 12/12/2006
• Status: Active Grant

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Casanova, R. Michael, Talpade, Dnyanesh A., Pathak, Chandrashekhar P.
• Primary Examiner(s): Lamprecht, Joel
• Application Number:
  US15/410,869
• Publication Number:
  US 20170128154A1
• Time in Patent Office: 403 Days
• CPC Class Codes: A61B 2090/376 using X-rays, e.g. fluoroscopy
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 2090/3995 Multi-modality markers
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

An intracorporeal tissue marker includes a first material comprising a core region of the marker. The first material has a first density. A second material completely surrounds the first material. The second material is distinct from the first material and has a second density. The first density of the first material is lower than the second density of the second material.

Claims

1. An intracorporeal tissue marker, comprising:

a first material comprising a core region of the marker, the first material having a first density; and

a second material completely surrounding the first material, the second material being distinct from the first material and having a second density, the first density of the first material being lower than the second density of the second material.

2. The intracorporeal marker of claim 1, wherein each of the first material and the second material is porous.

3. The intracorporeal marker of claim 1, further comprising a third material that is completely surrounded by the first material, the third material having a third density, the first density of the first material being lower than the third density of the third material.

4. The intracorporeal marker of claim 3, wherein each of the first material, the second material, and the third material is porous.

5. The intracorporeal marker of claim 3, wherein each of the first material, the second material, and the third material is porous and has porosity levels in a range of 30 percent to 80 percent, and each of the second material and the third material has respective porosity levels that are lower than the porosity levels of the first material.

6. An intracorporeal marker for marking a site within living tissue of a host, comprising a body formed from a single material, the body having a central region, an intermediate region, and a surface region, wherein a density of the body decreases from the central region to the intermediate region, and the density of the body increases at the surface region from the intermediate region.

7. The intracorporeal marker of claim 6, wherein the body has pores filled with gas, the sizes of the pores filled with the gas being such that the body is configured to be visualized under ultrasound.

8. The intracorporeal marker of claim 7, wherein the gas is carbon dioxide.

9. The intracorporeal marker of claim 8, wherein the body has porosity levels in a range of 30 percent to 80 percent.

10. The intracorporeal marker of claim 6, wherein the body has porosity levels in a range of 30 percent to 80 percent.

11. The intracorporeal marker of claim 6, wherein the intermediate region completely surrounds the central region and the surface region completely surrounds the intermediate region.

12. An intracorporeal marker for marking a site within living tissue of a host, comprising a body formed from a single material, the body having a central region, an intermediate region, and a surface region, wherein the central region has a first density, the intermediate region has a second density, and the surface region has a third density, wherein a density of the intermediate region is less than each of the central region and the surface region.

13. The intracorporeal marker of claim 12, wherein the body has pores filled with gas, the sizes of the pores filled with the gas being such that the body is configured to be visualized under ultrasound.

14. The intracorporeal marker of claim 13, wherein the gas is carbon dioxide.

15. The intracorporeal marker of claim 14, wherein the body has porosity levels in a range of 30 percent to 80 percent.

16. The intracorporeal marker of claim 12, wherein the body has porosity levels in a range of 30 percent to 80 percent.

17. The intracorporeal marker of claim 12, wherein the intermediate region completely surrounds the central region and the surface region completely surrounds the intermediate region.