System for use in bone cement preparation and delivery

• US 9,901,657 B2
• Filed: 07/11/2014
• Issued: 02/27/2018
• Est. Priority Date: 10/13/2008
• Status: Active Grant

• Current Assignee: Dfine Incorporated (Merit Medical Systems, Inc.)
• Original Assignee: Dfine Incorporated (Merit Medical Systems, Inc.)
• Inventors: Kwan, Harry, Kohm, Andrew, Truckai, Csaba
• Primary Examiner(s): Cleveland, Timothy C
• Application Number:
  US14/329,335
• Publication Number:
  US 20140323662A1
• Time in Patent Office: 1,327 Days
• CPC Class Codes: A61B 17/8827 with filtering, degassing, venting or pressure relief means
• CPC Class Codes: A61B 17/8833 Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
• CPC Class Codes: A61F 2002/3008 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61L 24/001 Use of materials characterised by their function or physical properties
• CPC Class Codes: A61L 24/06 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L24/043, A61L24/046 take precedence
• CPC Class Codes: B01F 2101/20 Mixing of ingredients for bone cement
• CPC Class Codes: B01F 23/54 wetting solids
• CPC Class Codes: B01F 33/5011 portable during use, e.g. hand-held
• CPC Class Codes: B01F 33/50111 Small portable bottles, flasks, vials, e.g. with means for mixing ingredients or for homogenizing their content, e.g. by hand shaking
• CPC Class Codes: B01F 33/50112 of the syringe or cartridge type
• CPC Class Codes: B01F 35/712 for feeding fluids
• CPC Class Codes: B01F 35/718 using vacuum, under pressure in a closed receptacle or circuit system
• CPC Class Codes: B01F 35/754251 reciprocating in the mixing receptacle
• CPC Class Codes: B29B 7/94 Liquid charges

Abstract

A system for use in bone cement preparation can include a chamber for intermixing a liquid monomer and solid polymer components, a container, a vacuum channel, and a filter. The mixing chamber can be configured to hold a non-liquid, polymer powder component of a bone cement. The container can be configured to hold a liquid component of the bone cement. The system can have a first interface disposed between the mixing chamber and the container and a second interface disposed between the mixing chamber and the vacuum channel. The second interface can to receive and position the filter between the mixing chamber and the vacuum channel. The vacuum channel can direct a partial vacuum to draw the liquid component from the container into the non-liquid component in the mixing chamber to intermix the components and to thereby provide a settable bone cement.

Claims

1. A bone cement preparation system comprising:

a liquid container configured to receive a liquid component of a bone cement from an external source and further configured to release the liquid component therefrom;

a mixing chamber configured to receive through a first opening and hold therein a non-liquid component of the bone cement from an external source, wherein the first opening is disposed at a first end of the mixing chamber and is further configured to couple to the liquid container to receive and hold the liquid component released therefrom to form a settable bone cement mixture comprising the liquid component and the non-liquid component, the mixing chamber further having a second opening that is disposed at a second end of the mixing chamber; and

a filter configured to couple to the second opening of the mixing chamber, wherein the filter comprises a plurality of pores that are configured to prevent passage of the bone cement mixture therethrough while allowing passage of air or gas therethough,

wherein the system comprises a flow path that extends from the liquid container through the first opening of the mixing chamber to the second opening of the mixing chamber, wherein the direction of the flow path is linear.

2. The bone cement preparation system of claim 1, wherein the pores are configured to swell upon coming into contact with the bone cement to prevent the passage of the bone cement mixture therethrough while allowing the passage of air or gas therethough.

3. The bone cement preparation system of claim 1, wherein the pores have an average pore size between about 0.05 microns and about 10 microns.

4. The bone cement preparation system of claim 1, further comprising a pressure source configured to apply a pressure to the liquid component in the liquid container to cause the liquid component to be transferred into the mixing chamber and combine with the non-liquid component, while causing air in the mixing chamber to be removed through the filter.

5. The bone cement preparation system of claim 4, wherein the pressure source is a negative pressure source comprising a vacuum source.

6. The bone cement preparation system of claim 5, wherein the vacuum source is configured to be coupled to the mixing chamber through the filter, wherein the vacuum source comprises a vacuum channel configured to form a partial vacuum therein to draw the liquid component from the liquid container into the mixing chamber.

7. The bone cement preparation system of claim 1, further comprising the non-liquid component and the liquid component combinable to form the settable bone cement.

8. The bone cement preparation system of claim 7, wherein the non-liquid component comprises polymer particles and initiators, wherein the liquid component comprises monomers, and wherein the settable bone cement is configured to initiate setting at least in part by polymerization of monomers initiated by the initiators.

9. The bone cement preparation system of claim 8, wherein an average pore size of the filter is smaller than an average diameter of the polymer particles.

10. The bone cement preparation system of claim 1, wherein the liquid container comprises a funnel.

11. A system comprising:

a liquid container configured to receive a liquid component of a settable bone fill material from an external source and further configured to release the liquid component therefrom;

a mixing chamber configured to receive through a first opening and hold therein a non-liquid component of the bone fill material from an external source, wherein the first opening is disposed at a first end of the mixing chamber and is further configured to couple to the liquid container to receive and hold the liquid component released therefrom to form a settable bone fill material comprising the liquid component and the non-liquid component, the mixing chamber further having a second opening that is disposed at a second end of the mixing chamber;

a pressure source configured to apply a pressure to the liquid component in the liquid container to transfer the liquid component from the liquid container into the mixing chamber to mix with the non-liquid component to form the settable bone fill material; and

a filter configured to couple to the second opening of the mixing chamber and configured to allow gas to pass therethrough, while being configured to inhibit the bone fill material from passing therethrough,

wherein the system comprises a flow path that extends from the liquid container through the first opening of the mixing chamber to the second opening of the mixing chamber, wherein the direction of the flow path is linear.

12. The system of claim 11, further comprising a bone fill material delivery device comprising:

a cannula for introducing the bone fill material into a bone;

and a driving system, wherein the mixing chamber is configured to couple to the driving system to deliver the bone fill material from the mixing chamber through the cannula and into a bone.

13. The system of claim 11, wherein the pressure source is a negative pressure source comprising a vacuum channel configured to be coupled to the mixing chamber, wherein the vacuum channel is configured to form a partial vacuum therein to draw the liquid component from the liquid container into the mixing chamber to combine with the non-liquid component.

14. The system of claim 13, further comprising a stopcock valve between the filter and the vacuum channel and configured to control application of negative pressure from the vacuum source to the chamber and container.

15. The system of claim 11, further comprising a pressure relief valve configured to limit the amount of the pressure applied to the liquid component.